(11 nodes) Nucleobase-containing compound kinase activity network (Bacillus oceanisediminis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A361_00115	Deoxycytidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
	A361_00120	Deoxyguanosine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
	tmk	dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (208 aa)
	adk	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (216 aa)
	gmk	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (204 aa)
	pyrH	UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa)
	A361_17580	Topology modulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
	ndk	Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (148 aa)
	cmk	Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
	udk	Uridine kinase; Functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
	tdk	Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)

Your Current Organism:

Bacillus oceanisediminis

NCBI taxonomy Id: 1196031
Other names: B. oceanisediminis 2691, Bacillus oceanisediminis 2691

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A361_00115	A361_00120	A361_00115	A361_00120	Deoxycytidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Deoxyguanosine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.896
A361_00115	adk	A361_00115	A361_00840	Deoxycytidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.915
A361_00115	cmk	A361_00115	A361_19560	Deoxycytidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.916
A361_00115	tdk	A361_00115	A361_26010	Deoxycytidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.694
A361_00115	tmk	A361_00115	A361_00205	Deoxycytidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.628
A361_00120	A361_00115	A361_00120	A361_00115	Deoxyguanosine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Deoxycytidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.896
A361_00120	gmk	A361_00120	A361_09395	Deoxyguanosine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.930
A361_00120	tdk	A361_00120	A361_26010	Deoxyguanosine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.663
A361_00120	tmk	A361_00120	A361_00205	Deoxyguanosine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.628
A361_17580	gmk	A361_17580	A361_09395	Topology modulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.700
A361_17580	pyrH	A361_17580	A361_09860	Topology modulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.493
adk	A361_00115	A361_00840	A361_00115	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Deoxycytidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.915
adk	gmk	A361_00840	A361_09395	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.749
adk	ndk	A361_00840	A361_19465	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.935
adk	pyrH	A361_00840	A361_09860	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.495
cmk	A361_00115	A361_19560	A361_00115	Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Deoxycytidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.916
cmk	gmk	A361_19560	A361_09395	Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.515
cmk	ndk	A361_19560	A361_19465	Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.927
cmk	pyrH	A361_19560	A361_09860	Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.436
cmk	udk	A361_19560	A361_21360	Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Uridine kinase; Functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.931