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| | accA | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa) |
| | serS | serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (425 aa) |
| | A361_00310 | Reactive intermediate/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa) |
| | A361_00445 | Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (309 aa) |
| | A361_00450 | Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa) |
| | A361_00460 | 4-amino-4-deoxychorismate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa) |
| | A361_00465 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (278 aa) |
| | A361_00470 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa) |
| | A361_00475 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa) |
| | A361_00625 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (280 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (372 aa) |
| | proA | Gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (422 aa) |
| | acpS | holo-ACP synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (117 aa) |
| | A361_01435 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (423 aa) |
| | A361_02195 | Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (454 aa) |
| | A361_02380 | Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa) |
| | A361_02385 | Petrobactin biosynthesis protein AsbE; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa) |
| | A361_02390 | 3-dehydroshikimate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa) |
| | A361_02455 | Glyoxal reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa) |
| | A361_03035 | Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa) |
| | asnA | Aspartate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa) |
| | A361_03280 | Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa) |
| | kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (422 aa) |
| | A361_05045 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (306 aa) |
| | A361_05095 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa) |
| | mtnK | S-methyl-5-thioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (407 aa) |
| | mtnA | S-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (353 aa) |
| | A361_05730 | Radical SAM/CxCxxxxC motif protein YfkAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa) |
| | A361_05965 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (535 aa) |
| | A361_06045 | Succinyl-diaminopimelate desuccinylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa) |
| | A361_06105 | enoyl-ACP reductase; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa) |
| | A361_06160 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1490 aa) |
| | A361_06425 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa) |
| | proC-2 | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (271 aa) |
| | A361_06470 | Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (556 aa) |
| | A361_06505 | Glyoxal reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa) |
| | A361_06890 | enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa) |
| | serC | 3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (360 aa) |
| | A361_07010 | Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa) |
| | A361_07170 | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa) |
| | A361_07265 | Asparagine synthetase B; Derived by automated computational analysis using gene prediction method: Protein Homology. (615 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (343 aa) |
| | argJ | N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (409 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (257 aa) |
| | argD | Acetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (385 aa) |
| | carA | Carbamoyl-phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (359 aa) |
| | carB | Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (1041 aa) |
| | A361_07425 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (318 aa) |
| | fabH | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (310 aa) |
| | A361_07490 | Beta-ketoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa) |
| | A361_07650 | enoyl-ACP reductase; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa) |
| | A361_07750 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa) |
| | A361_08385 | Enamine deaminase RidA; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa) |
| | A361_08390 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa) |
| | A361_08400 | Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa) |
| | mtnW | 2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P); Belongs to the RuBisCO large chain family. Type IV subfamily. (410 aa) |
| | mtnX | 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate phosphatase; Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene). (220 aa) |
| | mtnB | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (211 aa) |
| | mtnD | Acireductone dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (180 aa) |
| | A361_08500 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa) |
| | dapH | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (236 aa) |
| | A361_08740 | N-acetyldiaminopimelate deacetylase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. (374 aa) |
| | A361_08875 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa) |
| | A361_09125 | Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa) |
| | A361_09140 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (294 aa) |
| | carA-2 | Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa) |
| | carB-2 | Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1070 aa) |
| | fapR | Fatty acid biosynthesis transcriptional regulator; Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism. (186 aa) |
| | plsX | Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (334 aa) |
| | A361_09495 | Malonyl CoA-acyl carrier protein transacylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa) |
| | A361_09500 | beta-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (349 aa) |
| | A361_09990 | Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (414 aa) |
| | dapA | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (288 aa) |
| | fabG | 3-ketoacyl-ACP reductase; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa) |
| | A361_10255 | Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa) |
| | A361_10320 | Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa) |
| | A361_11150 | GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa) |
| | A361_11430 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa) |
| | A361_11455 | Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa) |
| | A361_11570 | uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa) |
| | A361_11625 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (471 aa) |
| | A361_11925 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa) |
| | A361_12060 | 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | hisC | Histidinol-phosphate transaminase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (364 aa) |
| | A361_12195 | 8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa) |
| | A361_12440 | Acetylornithine deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa) |
| | selD | Selenophosphate synthetase; Synthesizes selenophosphate from selenide and ATP. (316 aa) |
| | A361_12620 | Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa) |
| | A361_12640 | Fatty acid desaturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa) |
| | A361_12740 | 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa) |
| | A361_13090 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1148 aa) |
| | A361_13125 | Glyoxal reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa) |
| | A361_13460 | Nitrous oxidase accessory protein NosD; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa) |
| | leuC | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (475 aa) |
| | A361_13620 | Quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa) |
| | cysH | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (238 aa) |
| | A361_13750 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa) |
| | A361_13755 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa) |
| | A361_13875 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa) |
| | proA-2 | Gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (410 aa) |
| | proB-2 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (373 aa) |
| | A361_14280 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (573 aa) |
| | A361_14555 | Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa) |
| | A361_14560 | Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (331 aa) |
| | A361_14910 | Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa) |
| | A361_15030 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (76 aa) |
| | A361_15180 | Amino acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (544 aa) |
| | A361_15215 | Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (466 aa) |
| | A361_15235 | Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (437 aa) |
| | A361_15310 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa) |
| | A361_15455 | UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa) |
| | A361_15525 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa) |
| | A361_15530 | Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa) |
| | eutB | Hydroxyectoine utilization dehydratase EutB; Catalyzes the formation of 2-oxobutanoate from L-threonine; involved in ectoine utilization; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa) |
| | A361_15620 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa) |
| | A361_15715 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa) |
| | A361_15805 | Gluconolaconase; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa) |
| | A361_15890 | Hydantoin racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa) |
| | A361_15950 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa) |
| | A361_16490 | Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa) |
| | A361_16605 | Sugar phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa) |
| | A361_16945 | Sulfoacetaldehyde acetyltransferase; Catalyzes the formation of acetyl phosphate and sulfite from 2-sulfoacetaldehyde; is active when grown on taurine as a sole carbon source; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (589 aa) |
| | A361_16950 | Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa) |
| | A361_17070 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa) |
| | A361_17180 | 5'-methylthioadenosine nucleosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa) |
| | A361_17205 | 3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (399 aa) |
| | A361_17515 | Serine-pyruvate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa) |
| | cysI | Sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (573 aa) |
| | A361_17530 | Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (603 aa) |
| | trpA | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (261 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (401 aa) |
| | trpF | N-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (206 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (264 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (341 aa) |
| | trpE | Anthranilate synthase subunit I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrat [...] (464 aa) |
| | bioB | Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (330 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (327 aa) |
| | fabG-4 | 3-ketoacyl-ACP reductase; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa) |
| | A361_18545 | GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa) |
| | A361_18675 | Putative beta-lysine N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa) |
| | A361_18705 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (422 aa) |
| | A361_18825 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (161 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (556 aa) |
| | metAA | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (302 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (127 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (285 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (278 aa) |
| | A361_19330 | N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa) |
| | A361_19335 | Bacillithiol biosynthesis deacetylase BshB1; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa) |
| | dapB | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (267 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (431 aa) |
| | A361_19435 | Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa) |
| | hisC-2 | Histidinol-phosphate transaminase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (366 aa) |
| | A361_19445 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (124 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (358 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (390 aa) |
| | A361_19680 | Histidinol phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PHP hydrolase family. HisK subfamily. (270 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (439 aa) |
| | A361_19940 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (72 aa) |
| | proC-3 | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (276 aa) |
| | argR | Arginine repressor; Regulates arginine biosynthesis genes. (149 aa) |
| | folD-2 | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (291 aa) |
| | A361_20200 | acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa) |
| | A361_20205 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (168 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (148 aa) |
| | lipM | Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation. (278 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (165 aa) |
| | A361_21255 | Late competence protein ComER; May be involved in regulation of competence genes; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (279 aa) |
| | mtnN | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (232 aa) |
| | A361_21450 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa) |
| | nadA | Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (368 aa) |
| | pheA | Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa) |
| | A361_21775 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (260 aa) |
| | leuD-2 | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa) |
| | leuC-2 | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (471 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (370 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (514 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (340 aa) |
| | A361_21875 | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa) |
| | A361_21880 | Acetolactate synthase 2 catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa) |
| | A361_21955 | Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (409 aa) |
| | accD | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (292 aa) |
| | argH | Argininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa) |
| | argG | Argininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (402 aa) |
| | A361_22375 | acyl--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (529 aa) |
| | A361_22405 | Catalyzes the formation of L-histidinol from L-histidinol phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PHP hydrolase family. HisK subfamily. (264 aa) |
| | A361_22610 | Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa) |
| | A361_22750 | Asparagine synthetase B; Derived by automated computational analysis using gene prediction method: Protein Homology. (634 aa) |
| | menF | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. (468 aa) |
| | A361_23310 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (60 aa) |
| | A361_23315 | Asparagine synthetase B; Derived by automated computational analysis using gene prediction method: Protein Homology. (647 aa) |
| | rocD | Ornithine--oxo-acid transaminase; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (399 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (311 aa) |
| | A361_23750 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (353 aa) |
| | A361_23755 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (305 aa) |
| | hisI | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. (214 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (212 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (423 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (214 aa) |
| | hisZ | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (394 aa) |
| | A361_24935 | UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa) |
| | A361_25080 | Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa) |
| | A361_25100 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (336 aa) |
| | argH-2 | Argininosuccinate lyase; Catalyzes the formation of arginine and fumarate from arginosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa) |
| | hisD-2 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (427 aa) |
| | A361_25320 | Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa) |
| | A361_25340 | Fatty acid desaturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa) |
| | A361_25410 | Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (424 aa) |
| | A361_25425 | Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa) |
| | fabZ | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (142 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (413 aa) |
| | A361_25970 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa) |
| | lipL | Octanoyltransferase; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes; Belongs to the octanoyltransferase LipL family. (280 aa) |
