STRINGSTRING
proA proA A361_02330 A361_02330 A361_03020 A361_03020 A361_03835 A361_03835 A361_03945 A361_03945 A361_04800 A361_04800 A361_06105 A361_06105 A361_06425 A361_06425 A361_08610 A361_08610 dxr dxr asd asd A361_11420 A361_11420 A361_11545 A361_11545 A361_13865 A361_13865 proA-2 proA-2 A361_14270 A361_14270 A361_15525 A361_15525 A361_15675 A361_15675 zwf zwf A361_15735 A361_15735 cysI cysI A361_17695 A361_17695 A361_18450 A361_18450 A361_18825 A361_18825 dapB dapB fni fni namA namA zwf-2 zwf-2 A361_20020 A361_20020 aroE aroE hemA hemA ilvC ilvC A361_22125 A361_22125 A361_23710 A361_23710 A361_23755 A361_23755 A361_24230 A361_24230 A361_26640 A361_26640
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
proAGamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (422 aa)
A361_02330Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
A361_03020ferredoxin--NADP(+) reductase; Catalyzes the oxidation of ferredoxin with NADP; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
A361_03835Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
A361_03945Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (96 aa)
A361_04800Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
A361_06105enoyl-ACP reductase; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
A361_06425Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
A361_08610Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
dxr1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (380 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (349 aa)
A361_11420Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
A361_115453-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
A361_138653-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
proA-2Gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (410 aa)
A361_14270Aspartate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
A361_15525Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
A361_156756-phosphogluconate dehydrogenase; Similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (484 aa)
A361_15735Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (119 aa)
cysISulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (573 aa)
A361_17695BRAMP protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
A361_18450Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (365 aa)
A361_18825Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (161 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (267 aa)
fniType 2 isopentenyl-diphosphate Delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (353 aa)
namANADPH dehydrogenase; Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes; Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily. (339 aa)
zwf-2Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (489 aa)
A361_20020Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (469 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (279 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (449 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (340 aa)
A361_22125Type I glyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (343 aa)
A361_23710ferredoxin--NADP(+) reductase; Catalyzes the oxidation of ferredoxin with NADP; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
A361_23755Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
A361_24230Type I glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
A361_26640Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa)
Your Current Organism:
Bacillus oceanisediminis
NCBI taxonomy Id: 1196031
Other names: B. oceanisediminis 2691, Bacillus oceanisediminis 2691
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