(46 nodes) Rossmann-like alpha/beta/alpha sandwich fold network (Talaromyces amestolkiae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BHQ10_000013	CTP_transf_like domain-containing protein. (448 aa)
	BHQ10_000088	Glutamine amidotransferase type-2 domain-containing protein. (575 aa)
	BHQ10_000136	CTP_transf_like domain-containing protein. (289 aa)
	BHQ10_000278	CTP_transf_like domain-containing protein. (477 aa)
	BHQ10_000602	Carrier domain-containing protein. (1830 aa)
	BHQ10_001211	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1000 aa)
	BHQ10_001551	Asparagine synthetase domain-containing protein. (353 aa)
	BHQ10_002174	Uncharacterized protein. (1035 aa)
	BHQ10_002314	Tyrosine--tRNA ligase. (389 aa)
	BHQ10_002408	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1051 aa)
	BHQ10_002656	Uncharacterized protein. (416 aa)
	BHQ10_002671	ETF domain-containing protein. (349 aa)
	BHQ10_003017	tRNA-synt_1g domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (506 aa)
	BHQ10_003078	MFS domain-containing protein. (615 aa)
	BHQ10_003269	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (681 aa)
	BHQ10_003713	Usp domain-containing protein. (675 aa)
	BHQ10_003830	CN hydrolase domain-containing protein. (1068 aa)
	NCS2	Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (354 aa)
	BHQ10_004331	Uncharacterized protein. (272 aa)
	BHQ10_004426	Usp domain-containing protein. (430 aa)
	BHQ10_004913	Uncharacterized protein. (1123 aa)
	BHQ10_005751	Uncharacterized protein. (370 aa)
	BHQ10_005938	ATP_bind_3 domain-containing protein. (633 aa)
	BHQ10_006282	Photolyase/cryptochrome alpha/beta domain-containing protein. (1372 aa)
	BHQ10_006296	Tyrosine--tRNA ligase. (602 aa)
	BHQ10_006344	Uncharacterized protein. (542 aa)
	BHQ10_006554	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (625 aa)
	BHQ10_006767	tRNA-synt_1c domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (512 aa)
	BHQ10_007057	Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. (280 aa)
	BHQ10_007324	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (448 aa)
	BHQ10_007480	CTP_transf_like domain-containing protein. (390 aa)
	BHQ10_007393	Diphthami_syn_2 domain-containing protein. (765 aa)
	BHQ10_007635	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (715 aa)
	BHQ10_007703	Uncharacterized protein. (797 aa)
	BHQ10_008057	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (932 aa)
	BHQ10_008100	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (867 aa)
	BHQ10_008521	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (632 aa)
	BHQ10_008642	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1066 aa)
	BHQ10_008826	PAPS_reduct domain-containing protein. (305 aa)
	MET3	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa)
	BHQ10_008887	Photolyase/cryptochrome alpha/beta domain-containing protein. (635 aa)
	BHQ10_009099	Tyrosine--tRNA ligase. (378 aa)
	BHQ10_009372	Glutamine amidotransferase type-2 domain-containing protein. (712 aa)
	BHQ10_009684	ETF domain-containing protein. (261 aa)
	BHQ10_009888	DALR_1 domain-containing protein. (1055 aa)
	NCS6	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (417 aa)

Your Current Organism:

Talaromyces amestolkiae

NCBI taxonomy Id: 1196081
Other names: CBS 132696, CBS H-21050, DTO 179F5, DTO179F5, Penicillium sp. CBS 263.93, Penicillium sp. CBS 274.95, Penicillium sp. GT11, T. amestolkiae, Talaromyces amestolkae, Talaromyces amestolkiae Yilmaz, Houbraken, Frisvad & Samson 2012, Talaromyces sp CMV-2012a

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BHQ10_000088	BHQ10_002174	A0A364KKK1	A0A364KRH9	Glutamine amidotransferase type-2 domain-containing protein.	Uncharacterized protein.	0.462
BHQ10_000088	BHQ10_002656	A0A364KKK1	A0A364KSW2	Glutamine amidotransferase type-2 domain-containing protein.	Uncharacterized protein.	0.895
BHQ10_000088	BHQ10_003269	A0A364KKK1	A0A364KUM4	Glutamine amidotransferase type-2 domain-containing protein.	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.414
BHQ10_000136	BHQ10_003078	A0A364KKQ4	A0A364KU34	CTP_transf_like domain-containing protein.	MFS domain-containing protein.	0.682
BHQ10_000136	BHQ10_003830	A0A364KKQ4	A0A364KW89	CTP_transf_like domain-containing protein.	CN hydrolase domain-containing protein.	0.907
BHQ10_000136	BHQ10_007057	A0A364KKQ4	A0A364L5F2	CTP_transf_like domain-containing protein.	Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family.	0.893
BHQ10_000602	BHQ10_001211	A0A364KM17	A0A364KNU1	Carrier domain-containing protein.	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.857
BHQ10_000602	BHQ10_002174	A0A364KM17	A0A364KRH9	Carrier domain-containing protein.	Uncharacterized protein.	0.857
BHQ10_000602	BHQ10_002314	A0A364KM17	A0A364KRW5	Carrier domain-containing protein.	Tyrosine--tRNA ligase.	0.670
BHQ10_000602	BHQ10_002408	A0A364KM17	A0A364KS65	Carrier domain-containing protein.	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.659
BHQ10_000602	BHQ10_003017	A0A364KM17	A0A364KTX1	Carrier domain-containing protein.	tRNA-synt_1g domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.820
BHQ10_000602	BHQ10_003269	A0A364KM17	A0A364KUM4	Carrier domain-containing protein.	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.823
BHQ10_000602	BHQ10_004913	A0A364KM17	A0A364KZI5	Carrier domain-containing protein.	Uncharacterized protein.	0.878
BHQ10_000602	BHQ10_006296	A0A364KM17	A0A364L3D0	Carrier domain-containing protein.	Tyrosine--tRNA ligase.	0.699
BHQ10_000602	BHQ10_006344	A0A364KM17	A0A364L3E5	Carrier domain-containing protein.	Uncharacterized protein.	0.839
BHQ10_000602	BHQ10_006554	A0A364KM17	A0A364L412	Carrier domain-containing protein.	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.827
BHQ10_000602	BHQ10_006767	A0A364KM17	A0A364L4L4	Carrier domain-containing protein.	tRNA-synt_1c domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.842
BHQ10_000602	BHQ10_007324	A0A364KM17	A0A364L683	Carrier domain-containing protein.	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.573
BHQ10_000602	BHQ10_007635	A0A364KM17	A0A364L781	Carrier domain-containing protein.	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.843
BHQ10_000602	BHQ10_007703	A0A364KM17	A0A364L7M2	Carrier domain-containing protein.	Uncharacterized protein.	0.633

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