(83 nodes) Propanoate metabolism network (Talaromyces amestolkiae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BHQ10_004241	Epimerase domain-containing protein. (347 aa)
	BHQ10_004033	Uncharacterized protein. (253 aa)
	BHQ10_003893	Uncharacterized protein. (371 aa)
	BHQ10_003596	Uncharacterized protein. (679 aa)
	BHQ10_003557	Epimerase domain-containing protein. (341 aa)
	BHQ10_003536	Epimerase domain-containing protein. (343 aa)
	BHQ10_003442	Uncharacterized protein. (475 aa)
	BHQ10_003228	Uncharacterized protein. (371 aa)
	BHQ10_001562	Uncharacterized protein. (331 aa)
	BHQ10_008497	Uncharacterized protein. (2029 aa)
	BHQ10_008241	Uncharacterized protein. (427 aa)
	BHQ10_007987	Uncharacterized protein. (295 aa)
	BHQ10_007849	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (276 aa)
	BHQ10_007693	BZIP domain-containing protein. (940 aa)
	BHQ10_007652	Epimerase domain-containing protein. (363 aa)
	BHQ10_007617	3Beta_HSD domain-containing protein. (333 aa)
	BHQ10_007468	3Beta_HSD domain-containing protein. (340 aa)
	BHQ10_007474	Epimerase domain-containing protein. (372 aa)
	BHQ10_007434	Epimerase domain-containing protein. (359 aa)
	BHQ10_007206	Uncharacterized protein. (644 aa)
	BHQ10_007126	Uncharacterized protein. (2294 aa)
	BHQ10_008754	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
	BHQ10_008788	SET domain-containing protein. (369 aa)
	BHQ10_008883	Uncharacterized protein. (192 aa)
	BHQ10_009043	Uncharacterized protein. (297 aa)
	BHQ10_009184	Uncharacterized protein. (233 aa)
	BHQ10_009316	Uncharacterized protein. (170 aa)
	BHQ10_009362	Pyr_redox_2 domain-containing protein. (315 aa)
	BHQ10_009359	Uncharacterized protein. (580 aa)
	BHQ10_009411	ADH_N domain-containing protein. (414 aa)
	BHQ10_009516	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (283 aa)
	BHQ10_009675	Uncharacterized protein. (934 aa)
	BHQ10_009704	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (330 aa)
	BHQ10_009788	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (670 aa)
	BHQ10_009763	Uncharacterized protein. (322 aa)
	BHQ10_009918	Uncharacterized protein. (167 aa)
	BHQ10_010347	Epimerase domain-containing protein. (344 aa)
	BHQ10_010283	Uncharacterized protein. (326 aa)
	BHQ10_008664	Uncharacterized protein. (188 aa)
	BHQ10_006712	Epimerase domain-containing protein. (352 aa)
	BHQ10_006614	Uncharacterized protein. (468 aa)
	BHQ10_006427	ACAS_N domain-containing protein. (128 aa)
	BHQ10_006228	Epimerase domain-containing protein. (335 aa)
	BHQ10_006227	Uncharacterized protein. (435 aa)
	BHQ10_006197	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (296 aa)
	BHQ10_006036	Epimerase domain-containing protein. (341 aa)
	BHQ10_005998	Uncharacterized protein. (297 aa)
	BHQ10_005893	Transket_pyr domain-containing protein. (388 aa)
	BHQ10_005898	Epimerase domain-containing protein. (342 aa)
	BHQ10_005713	Uncharacterized protein. (782 aa)
	BHQ10_005694	Epimerase domain-containing protein. (343 aa)
	BHQ10_005280	Uncharacterized protein. (342 aa)
	BHQ10_005053	Aldedh domain-containing protein. (471 aa)
	BHQ10_005052	NAD_binding_11 domain-containing protein. (154 aa)
	BHQ10_005012	PLD phosphodiesterase domain-containing protein. (637 aa)
	BHQ10_004927	Uncharacterized protein. (1283 aa)
	BHQ10_004766	Uncharacterized protein. (173 aa)
	BHQ10_004667	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (440 aa)
	BHQ10_004402	Dihydrolipoyl dehydrogenase. (510 aa)
	BHQ10_004356	Epimerase domain-containing protein. (359 aa)
	BHQ10_004298	MaoC-like domain-containing protein. (903 aa)
	BHQ10_000116	Uncharacterized protein. (312 aa)
	BHQ10_000223	Uncharacterized protein. (370 aa)
	BHQ10_000441	Probable acetate kinase. (415 aa)
	BHQ10_000554	Uncharacterized protein. (271 aa)
	BHQ10_000747	Epimerase domain-containing protein. (339 aa)
	BHQ10_000779	Uncharacterized protein. (583 aa)
	BHQ10_001102	Uncharacterized protein. (566 aa)
	BHQ10_001093	3Beta_HSD domain-containing protein. (349 aa)
	BHQ10_001170	Epimerase domain-containing protein. (347 aa)
	BHQ10_001245	Uncharacterized protein. (748 aa)
	BHQ10_001250	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (428 aa)
	BHQ10_003056	Epimerase domain-containing protein. (355 aa)
	BHQ10_002442	Epimerase domain-containing protein. (344 aa)
	BHQ10_002398	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (448 aa)
	BHQ10_002249	Uncharacterized protein. (315 aa)
	BHQ10_002157	Uncharacterized protein. (499 aa)
	BHQ10_001898	MaoC-like domain-containing protein. (850 aa)
	BHQ10_001890	Aldedh domain-containing protein. (586 aa)
	BHQ10_001777	Acetyl-coenzyme A synthetase. (668 aa)
	BHQ10_001643	CoA_binding domain-containing protein. (1318 aa)
	BHQ10_001688	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (486 aa)
	BHQ10_001436	Uncharacterized protein. (354 aa)

Your Current Organism:

Talaromyces amestolkiae

NCBI taxonomy Id: 1196081
Other names: CBS 132696, CBS H-21050, DTO 179F5, DTO179F5, Penicillium sp. CBS 263.93, Penicillium sp. CBS 274.95, Penicillium sp. GT11, T. amestolkiae, Talaromyces amestolkae, Talaromyces amestolkiae Yilmaz, Houbraken, Frisvad & Samson 2012, Talaromyces sp CMV-2012a

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BHQ10_000441	BHQ10_001777	A0A364KLK3	A0A364KQE2	Probable acetate kinase.	Acetyl-coenzyme A synthetase.	0.898
BHQ10_000441	BHQ10_006427	A0A364KLK3	A0A364L3M2	Probable acetate kinase.	ACAS_N domain-containing protein.	0.831
BHQ10_000441	BHQ10_007206	A0A364KLK3	A0A364L5W4	Probable acetate kinase.	Uncharacterized protein.	0.831
BHQ10_000779	BHQ10_001245	A0A364KMJ5	A0A364KNV4	Uncharacterized protein.	Uncharacterized protein.	0.780
BHQ10_000779	BHQ10_001250	A0A364KMJ5	A0A364KNV9	Uncharacterized protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.780
BHQ10_000779	BHQ10_001643	A0A364KMJ5	A0A364KQ46	Uncharacterized protein.	CoA_binding domain-containing protein.	0.562
BHQ10_000779	BHQ10_001688	A0A364KMJ5	A0A364KQ37	Uncharacterized protein.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.737
BHQ10_000779	BHQ10_001777	A0A364KMJ5	A0A364KQE2	Uncharacterized protein.	Acetyl-coenzyme A synthetase.	0.699
BHQ10_000779	BHQ10_001890	A0A364KMJ5	A0A364KQQ1	Uncharacterized protein.	Aldedh domain-containing protein.	0.656
BHQ10_000779	BHQ10_001898	A0A364KMJ5	A0A364KQR8	Uncharacterized protein.	MaoC-like domain-containing protein.	0.815
BHQ10_000779	BHQ10_002249	A0A364KMJ5	A0A364KRR3	Uncharacterized protein.	Uncharacterized protein.	0.776
BHQ10_000779	BHQ10_002398	A0A364KMJ5	A0A364KS56	Uncharacterized protein.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.611
BHQ10_000779	BHQ10_003442	A0A364KMJ5	A0A364KV50	Uncharacterized protein.	Uncharacterized protein.	0.463
BHQ10_000779	BHQ10_004033	A0A364KMJ5	A0A364KWZ9	Uncharacterized protein.	Uncharacterized protein.	0.776
BHQ10_000779	BHQ10_004298	A0A364KMJ5	A0A364KXJ7	Uncharacterized protein.	MaoC-like domain-containing protein.	0.815
BHQ10_000779	BHQ10_004402	A0A364KMJ5	A0A364KXV7	Uncharacterized protein.	Dihydrolipoyl dehydrogenase.	0.463
BHQ10_000779	BHQ10_004667	A0A364KMJ5	A0A364KYN3	Uncharacterized protein.	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.460
BHQ10_000779	BHQ10_004766	A0A364KMJ5	A0A364KYZ1	Uncharacterized protein.	Uncharacterized protein.	0.686
BHQ10_000779	BHQ10_005052	A0A364KMJ5	A0A364KZR0	Uncharacterized protein.	NAD_binding_11 domain-containing protein.	0.674
BHQ10_000779	BHQ10_005053	A0A364KMJ5	A0A364KZX0	Uncharacterized protein.	Aldedh domain-containing protein.	0.656

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