STRINGSTRING
KTC10268.1 KTC10268.1 nth nth KTC21300.1 KTC21300.1 KTC21301.1 KTC21301.1 KTC13210.1 KTC13210.1 KTC20401.1 KTC20401.1 KTC20157.1 KTC20157.1 KTC25885.1 KTC25885.1 KTC15922.1 KTC15922.1 ligA ligA KTC24685.1 KTC24685.1 KTC21982.1 KTC21982.1 KTC21983.1 KTC21983.1 KTC10906.1 KTC10906.1 KTC11005.1 KTC11005.1 ung ung KTC19126.1 KTC19126.1 mutM mutM polA polA ligB ligB KTC10146.1 KTC10146.1 KTC19402.1 KTC19402.1 KTC20142.1 KTC20142.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KTC10268.13-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (212 aa)
KTC21300.1DNA ligase-associated DEXH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
KTC21301.1ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (544 aa)
KTC13210.15'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
KTC20401.1DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
KTC20157.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
KTC25885.13-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
KTC15922.16-O-methylguanine DNA methyltransferase; Regulates genes involved in the repair of alkylated DNA; repairs DNA containing 6-O-methylguanine; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
ligAAromatic ring-opening dioxygenase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (785 aa)
KTC24685.1Energy transducer TonB; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
KTC21982.1Metal-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (81 aa)
KTC21983.16-O-methylguanine DNA methyltransferase; Regulates genes involved in the repair of alkylated DNA; repairs DNA containing 6-O-methylguanine; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
KTC10906.13-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
KTC11005.1Exonuclease III; Removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
unguracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (230 aa)
KTC19126.1Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (166 aa)
mutM5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (270 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (928 aa)
ligBAromatic ring-opening dioxygenase LigA; Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily. (553 aa)
KTC10146.1Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
KTC19402.1A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (355 aa)
KTC20142.13-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA glycosylase MPG family. (227 aa)
Your Current Organism:
Pseudomonas marginalis
NCBI taxonomy Id: 1198317
Other names: P. marginalis ICMP 9505, Pseudomonas marginalis ICMP 9505
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