STRINGSTRING
fba fba ACAM_0007 ACAM_0007 ACAM_0010 ACAM_0010 pckA pckA ACAM_0041 ACAM_0041 ACAM_0044 ACAM_0044 etfB etfB etfA etfA ACAM_0129 ACAM_0129 ACAM_0130 ACAM_0130 gap gap pgk pgk ACAM_0150 ACAM_0150 prpB prpB ACAM_0231 ACAM_0231 ACAM_0233 ACAM_0233 ACAM_0287 ACAM_0287 alkK alkK loxD loxD ACAM_0381 ACAM_0381 ACAM_0407 ACAM_0407 ACAM_0438 ACAM_0438 ACAM_0439 ACAM_0439 ACAM_0442 ACAM_0442 ppsA ppsA mdh mdh aspC aspC ACAM_0511 ACAM_0511 ACAM_0526 ACAM_0526 ACAM_0527 ACAM_0527 ACAM_0537 ACAM_0537 ACAM_0539 ACAM_0539 ACAM_0568 ACAM_0568 ACAM_0606 ACAM_0606 ACAM_0607 ACAM_0607 ACAM_0611 ACAM_0611 sdhB sdhB sdhD sdhD sdhC sdhC sdhA sdhA gcvH gcvH ACAM_0657 ACAM_0657 sucC sucC sucD sucD fbpA fbpA glmS glmS ACAM_0766 ACAM_0766 ACAM_0805 ACAM_0805 ACAM_0827 ACAM_0827 ACAM_0829 ACAM_0829 acsA acsA ACAM_0871 ACAM_0871 ACAM_0875 ACAM_0875 ACAM_0918 ACAM_0918 ACAM_0928 ACAM_0928 ACAM_0929 ACAM_0929 ACAM_0934 ACAM_0934 ACAM_0940 ACAM_0940 tpiA tpiA ACAM_0975 ACAM_0975 apgM apgM citB citB ACAM_1039 ACAM_1039 pdhD pdhD pdhC pdhC pdhB pdhB pdhA pdhA ACAM_1050 ACAM_1050 gcvT gcvT gltA gltA gapN gapN fumC fumC gyaR gyaR hmgA hmgA ACAM_1175 ACAM_1175 ACAM_1176 ACAM_1176 ACAM_1177 ACAM_1177 ACAM_1186 ACAM_1186 ACAM_1228 ACAM_1228 glyA glyA ACAM_1230 ACAM_1230 ACAM_1310 ACAM_1310 ACAM_1318 ACAM_1318 ACAM_1319 ACAM_1319 gcvPB gcvPB gcvPA gcvPA ACAM_1331 ACAM_1331 ACAM_1332 ACAM_1332 glnA glnA prpD prpD ACAM_1354 ACAM_1354 aspC-2 aspC-2 fadD fadD ACAM_1480 ACAM_1480 ACAM_1496 ACAM_1496 ACAM_1497 ACAM_1497 ACAM_1498 ACAM_1498 ACAM_1499 ACAM_1499 etfB-2 etfB-2 etfA-2 etfA-2 ACAM_1518 ACAM_1518 ACAM_1525 ACAM_1525 deoC deoC eno eno ACAM_1545 ACAM_1545 ACAM_1553 ACAM_1553 ACAM_1580 ACAM_1580 acsA-2 acsA-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fbaFructose-bisphosphate aldolase. (276 aa)
ACAM_0007ATP-dependent 6-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (310 aa)
ACAM_0010Carbohydrate kinase; Belongs to the FGGY kinase family. (506 aa)
pckAPhosphoenolpyruvate carboxykinase. (489 aa)
ACAM_0041Fumarylacetoacetate hydrolase. (283 aa)
ACAM_0044enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (251 aa)
etfBElectron transfer flavoprotein beta-subunit. (266 aa)
etfAElectron transfer flavoprotein alpha-subunit. (308 aa)
ACAM_0129NAD-dependent aldehyde dehydrogenase. (468 aa)
ACAM_0130ATP:cobalamin adenosyltransferase. (180 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase. (343 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (415 aa)
ACAM_0150HTH-type transcriptional regulator. (255 aa)
prpBCarboxyvinyl-carboxyphosphonate; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (308 aa)
ACAM_0231acyl-CoA dehydrogenase. (406 aa)
ACAM_0233acetyl-CoA hydrolase. (487 aa)
ACAM_0287Malate dehydrogenase. (446 aa)
alkKmedium-chain-fatty-acid--CoA ligase. (555 aa)
loxDD-lactate dehydrogenase. (473 aa)
ACAM_0381Pyruvate kinase; Belongs to the pyruvate kinase family. (458 aa)
ACAM_0407Acetamidase/formamidase. (377 aa)
ACAM_0438Transketolase. (322 aa)
ACAM_0439Transketolase. (252 aa)
ACAM_0442enoyl-CoA hydratase/isomerase. (259 aa)
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (821 aa)
mdhMalate dehydrogenase; Belongs to the LDH/MDH superfamily. (308 aa)
aspCAspartate aminotransferase. (401 aa)
ACAM_0511Isocitrate dehydrogenase. (434 aa)
ACAM_0526acyl-CoA dehydrogenase. (331 aa)
ACAM_0527Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (214 aa)
ACAM_0537Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate. (239 aa)
ACAM_0539Bifunctional phosphoglucose/phosphomannose. (331 aa)
ACAM_0568Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (540 aa)
ACAM_0606acetyl-CoA acetyltransferase. (397 aa)
ACAM_0607Predicted nucleic-acid-binding protein containing a Zn-ribbon. (180 aa)
ACAM_0611Glutamate synthase. (337 aa)
sdhBSuccinate dehydrogenase iron-sulfur subunit. (305 aa)
sdhDSuccinate dehydrogenase subunit D. (118 aa)
sdhCSuccinate dehydrogenase subunit C. (158 aa)
sdhASuccinate dehydrogenase flavoprotein subunit. (583 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (144 aa)
ACAM_0657Glycerate kinase. (448 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (378 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa)
fbpAFructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (387 aa)
glmSIsomerizing glucosamine-fructose-6-phosphate; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (617 aa)
ACAM_0766acyl-CoA dehydrogenase. (395 aa)
ACAM_0805Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (347 aa)
ACAM_0827fatty-acid-CoA ligase. (651 aa)
ACAM_0829fatty-acid-CoA ligase. (481 aa)
acsAAcetyl-coenzyme A synthetase. (657 aa)
ACAM_0871Hypothetical protein. (307 aa)
ACAM_0875NADP-dependent glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (418 aa)
ACAM_0918Mercuric reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (461 aa)
ACAM_09282-oxoglutarate ferredoxin oxidoreductase subunit. (309 aa)
ACAM_09292-oxoacid:ferredoxin oxidoreductase alpha. (642 aa)
ACAM_09343-hydroxyacyl-CoA dehydrogenase. (669 aa)
ACAM_0940Predicted oxidoreductase. (326 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (223 aa)
ACAM_0975Alcohol dehydrogenase. (314 aa)
apgM2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (427 aa)
citBAconitate hydratase. (903 aa)
ACAM_1039Oxidoreductase. (334 aa)
pdhDDihydrolipoyl dehydrogenase. (464 aa)
pdhCBranched-chain alpha-keto acid dehydrogenase E2. (415 aa)
pdhBPyruvate dehydrogenase E1 subunit beta. (325 aa)
pdhAPyruvate dehydrogenase E1 subunit alpha. (420 aa)
ACAM_1050acyl-CoA dehydrogenase. (389 aa)
gcvTGlycine cleavage system aminomethyltransferase. (375 aa)
gltACitrate synthase. (394 aa)
gapNNADP-dependent glyceraldehyde-3-phosphate. (510 aa)
fumCFumarate hydratase. (444 aa)
gyaRGlyoxylate reductase. (335 aa)
hmgA3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. (421 aa)
ACAM_1175Predicted nucleic-acid-binding protein containing a Zn-ribbon. (133 aa)
ACAM_11763-ketoacyl-CoA thiolase. (377 aa)
ACAM_1177hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. (364 aa)
ACAM_1186L-fucose isomerase. (430 aa)
ACAM_1228Oxidoreductase. (272 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (439 aa)
ACAM_1230Alcohol dehydrogenase. (390 aa)
ACAM_1310ATP-dependent glucokinase. (319 aa)
ACAM_1318ATP-dependent 6-phosphofructokinase. (313 aa)
ACAM_1319acetyl-CoA acetyltransferase. (406 aa)
gcvPBGlycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (521 aa)
gcvPAGlycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (465 aa)
ACAM_13312-oxoacid:ferredoxin oxidoreductase subunit alpha. (639 aa)
ACAM_13322-oxoglutarate ferredoxin oxidoreductase subunit beta. (318 aa)
glnAGlutamine synthetase. (458 aa)
prpD2-methylcitrate dehydratase. (458 aa)
ACAM_1354acyl-CoA dehydrogenase. (399 aa)
aspC-2Aspartate aminotransferase. (405 aa)
fadDlong-chain-fatty-acid-CoA ligase. (571 aa)
ACAM_1480acyl-CoA dehydrogenase. (405 aa)
ACAM_1496acetyl-CoA acetyltransferase. (385 aa)
ACAM_1497acetyl-CoA acetyltransferase. (394 aa)
ACAM_1498Predicted nucleic-acid-binding protein containing a Zn-ribbon. (182 aa)
ACAM_1499Predicted nucleic-acid-binding protein containing a Zn-ribbon. (154 aa)
etfB-2Electron transfer flavoprotein beta-subunit. (269 aa)
etfA-2Electron transfer flavoprotein alpha-subunit. (372 aa)
ACAM_1518FixC protein. (436 aa)
ACAM_1525Phospho-sugar mutase; Belongs to the phosphohexose mutase family. (489 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (235 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa)
ACAM_1545FixX protein. (92 aa)
ACAM_1553Propionate CoA-transferase. (554 aa)
ACAM_1580Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (336 aa)
acsA-2Acetyl-coenzyme A synthetase. (654 aa)
Your Current Organism:
Aeropyrum camini
NCBI taxonomy Id: 1198449
Other names: A. camini SY1 = JCM 12091, Aeropyrum camini JCM 12091, Aeropyrum camini JCM 12091 = SY1, Aeropyrum camini SY1, Aeropyrum camini SY1 = JCM 12091
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