STRINGSTRING
fba fba ACAM_0007 ACAM_0007 pckA pckA gap gap pgk pgk prpB prpB ACAM_0233 ACAM_0233 ACAM_0287 ACAM_0287 loxD loxD ACAM_0381 ACAM_0381 ACAM_0407 ACAM_0407 ACAM_0438 ACAM_0438 ACAM_0439 ACAM_0439 ppsA ppsA mdh mdh aspC aspC ACAM_0511 ACAM_0511 ACAM_0537 ACAM_0537 ACAM_0539 ACAM_0539 ACAM_0568 ACAM_0568 ACAM_0611 ACAM_0611 sdhB sdhB sdhD sdhD sdhC sdhC sdhA sdhA gcvH gcvH ACAM_0657 ACAM_0657 sucC sucC sucD sucD fbpA fbpA glmS glmS ACAM_0805 ACAM_0805 acsA acsA ACAM_0871 ACAM_0871 ACAM_0875 ACAM_0875 ACAM_0918 ACAM_0918 ACAM_0928 ACAM_0928 ACAM_0929 ACAM_0929 tpiA tpiA apgM apgM citB citB pdhD pdhD pdhC pdhC pdhB pdhB pdhA pdhA gcvT gcvT gltA gltA gapN gapN fumC fumC gyaR gyaR glyA glyA ACAM_1310 ACAM_1310 ACAM_1318 ACAM_1318 gcvPB gcvPB gcvPA gcvPA ACAM_1331 ACAM_1331 ACAM_1332 ACAM_1332 glnA glnA prpD prpD aspC-2 aspC-2 ACAM_1525 ACAM_1525 deoC deoC eno eno ACAM_1553 ACAM_1553 ACAM_1580 ACAM_1580 acsA-2 acsA-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fbaFructose-bisphosphate aldolase. (276 aa)
ACAM_0007ATP-dependent 6-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (310 aa)
pckAPhosphoenolpyruvate carboxykinase. (489 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase. (343 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (415 aa)
prpBCarboxyvinyl-carboxyphosphonate; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (308 aa)
ACAM_0233acetyl-CoA hydrolase. (487 aa)
ACAM_0287Malate dehydrogenase. (446 aa)
loxDD-lactate dehydrogenase. (473 aa)
ACAM_0381Pyruvate kinase; Belongs to the pyruvate kinase family. (458 aa)
ACAM_0407Acetamidase/formamidase. (377 aa)
ACAM_0438Transketolase. (322 aa)
ACAM_0439Transketolase. (252 aa)
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (821 aa)
mdhMalate dehydrogenase; Belongs to the LDH/MDH superfamily. (308 aa)
aspCAspartate aminotransferase. (401 aa)
ACAM_0511Isocitrate dehydrogenase. (434 aa)
ACAM_0537Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate. (239 aa)
ACAM_0539Bifunctional phosphoglucose/phosphomannose. (331 aa)
ACAM_0568Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (540 aa)
ACAM_0611Glutamate synthase. (337 aa)
sdhBSuccinate dehydrogenase iron-sulfur subunit. (305 aa)
sdhDSuccinate dehydrogenase subunit D. (118 aa)
sdhCSuccinate dehydrogenase subunit C. (158 aa)
sdhASuccinate dehydrogenase flavoprotein subunit. (583 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (144 aa)
ACAM_0657Glycerate kinase. (448 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (378 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa)
fbpAFructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (387 aa)
glmSIsomerizing glucosamine-fructose-6-phosphate; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (617 aa)
ACAM_0805Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (347 aa)
acsAAcetyl-coenzyme A synthetase. (657 aa)
ACAM_0871Hypothetical protein. (307 aa)
ACAM_0875NADP-dependent glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (418 aa)
ACAM_0918Mercuric reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (461 aa)
ACAM_09282-oxoglutarate ferredoxin oxidoreductase subunit. (309 aa)
ACAM_09292-oxoacid:ferredoxin oxidoreductase alpha. (642 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (223 aa)
apgM2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (427 aa)
citBAconitate hydratase. (903 aa)
pdhDDihydrolipoyl dehydrogenase. (464 aa)
pdhCBranched-chain alpha-keto acid dehydrogenase E2. (415 aa)
pdhBPyruvate dehydrogenase E1 subunit beta. (325 aa)
pdhAPyruvate dehydrogenase E1 subunit alpha. (420 aa)
gcvTGlycine cleavage system aminomethyltransferase. (375 aa)
gltACitrate synthase. (394 aa)
gapNNADP-dependent glyceraldehyde-3-phosphate. (510 aa)
fumCFumarate hydratase. (444 aa)
gyaRGlyoxylate reductase. (335 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (439 aa)
ACAM_1310ATP-dependent glucokinase. (319 aa)
ACAM_1318ATP-dependent 6-phosphofructokinase. (313 aa)
gcvPBGlycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (521 aa)
gcvPAGlycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (465 aa)
ACAM_13312-oxoacid:ferredoxin oxidoreductase subunit alpha. (639 aa)
ACAM_13322-oxoglutarate ferredoxin oxidoreductase subunit beta. (318 aa)
glnAGlutamine synthetase. (458 aa)
prpD2-methylcitrate dehydratase. (458 aa)
aspC-2Aspartate aminotransferase. (405 aa)
ACAM_1525Phospho-sugar mutase; Belongs to the phosphohexose mutase family. (489 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (235 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa)
ACAM_1553Propionate CoA-transferase. (554 aa)
ACAM_1580Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (336 aa)
acsA-2Acetyl-coenzyme A synthetase. (654 aa)
Your Current Organism:
Aeropyrum camini
NCBI taxonomy Id: 1198449
Other names: A. camini SY1 = JCM 12091, Aeropyrum camini JCM 12091, Aeropyrum camini JCM 12091 = SY1, Aeropyrum camini SY1, Aeropyrum camini SY1 = JCM 12091
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