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ACAM_1581 ACAM_1581 acsA-2 acsA-2 fba fba ACAM_0007 ACAM_0007 ACAM_0046 ACAM_0046 ACAM_0095 ACAM_0095 gap gap pgk pgk ACAM_0194 ACAM_0194 pyrD pyrD pyrC pyrC ACAM_0254 ACAM_0254 pyrH pyrH atpD atpD aptB aptB atpA atpA atpE atpE ACAM_0381 ACAM_0381 ACAM_0382 ACAM_0382 upp upp ACAM_0438 ACAM_0438 ACAM_0439 ACAM_0439 panB panB panE panE ACAM_0526 ACAM_0526 surE surE ACAM_0697 ACAM_0697 ACAM_0766 ACAM_0766 acsA acsA ACAM_0885 ACAM_0885 ACAM_0928 ACAM_0928 ACAM_0929 ACAM_0929 nudF nudF tpiA tpiA pyrG pyrG apgM apgM pyrB pyrB pdhC pdhC pdhB pdhB pdhA pdhA ACAM_1050 ACAM_1050 ACAM_1105 ACAM_1105 prs prs hmgA hmgA ACAM_1211 ACAM_1211 ACAM_1212 ACAM_1212 dfp dfp ACAM_1292 ACAM_1292 udp udp ACAM_1318 ACAM_1318 ribK ribK ACAM_1331 ACAM_1331 ACAM_1332 ACAM_1332 ACAM_1354 ACAM_1354 pyrF pyrF pyrE pyrE ndk ndk mvk mvk guaA guaA eno eno ACAM_1570 ACAM_1570
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACAM_1581Acetolactate synthase; Belongs to the TPP enzyme family. (558 aa)
acsA-2Acetyl-coenzyme A synthetase. (654 aa)
fbaFructose-bisphosphate aldolase. (276 aa)
ACAM_0007ATP-dependent 6-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (310 aa)
ACAM_0046Adenine/guanine phosphoribosyltransferase. (233 aa)
ACAM_0095Diadenosine tetraphosphate hydrolase. (177 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase. (343 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (415 aa)
ACAM_0194Uncharacterized protein conserved in archaea; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (182 aa)
pyrDDihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. (307 aa)
pyrCDihydroorotase. (426 aa)
ACAM_0254Acyl coenzyme A thioester hydrolase. (349 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (226 aa)
atpDV-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (211 aa)
aptBV-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (463 aa)
atpAV-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (597 aa)
atpEV-type ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (200 aa)
ACAM_0381Pyruvate kinase; Belongs to the pyruvate kinase family. (458 aa)
ACAM_0382Purine phosphoribosyltransferase. (229 aa)
uppUracil phosphoribosyltransferase. (213 aa)
ACAM_0438Transketolase. (322 aa)
ACAM_0439Transketolase. (252 aa)
panB3-methyl-2-oxobutanoate; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (274 aa)
panE2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (309 aa)
ACAM_0526acyl-CoA dehydrogenase. (331 aa)
surE5'(3')-nucleotidase SurE. (272 aa)
ACAM_0697Adenine/guanine phosphoribosyltransferase. (213 aa)
ACAM_0766acyl-CoA dehydrogenase. (395 aa)
acsAAcetyl-coenzyme A synthetase. (657 aa)
ACAM_0885Hypothetical protein. (346 aa)
ACAM_09282-oxoglutarate ferredoxin oxidoreductase subunit. (309 aa)
ACAM_09292-oxoacid:ferredoxin oxidoreductase alpha. (642 aa)
nudFADP-ribose pyrophosphatase. (183 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (223 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (538 aa)
apgM2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (427 aa)
pyrBAspartate carbamoyltransferase catalytic. (312 aa)
pdhCBranched-chain alpha-keto acid dehydrogenase E2. (415 aa)
pdhBPyruvate dehydrogenase E1 subunit beta. (325 aa)
pdhAPyruvate dehydrogenase E1 subunit alpha. (420 aa)
ACAM_1050acyl-CoA dehydrogenase. (389 aa)
ACAM_1105Adenylate cyclase class 2. (177 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (309 aa)
hmgA3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. (421 aa)
ACAM_1211Uncharacterized protein conserved in archaea. (261 aa)
ACAM_1212Predicted archaeal kinase. (279 aa)
dfpCoenzyme A biosynthesis bifunctional protein. (412 aa)
ACAM_1292Purine phosphoribosyltransferase. (273 aa)
udpUridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (282 aa)
ACAM_1318ATP-dependent 6-phosphofructokinase. (313 aa)
ribKTranscriptional regulator of a riboflavin/FAD biosynthetic operon; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (132 aa)
ACAM_13312-oxoacid:ferredoxin oxidoreductase subunit alpha. (639 aa)
ACAM_13322-oxoglutarate ferredoxin oxidoreductase subunit beta. (318 aa)
ACAM_1354acyl-CoA dehydrogenase. (399 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (239 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (186 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (141 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (324 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (512 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa)
ACAM_1570HIT family protein. (174 aa)
Your Current Organism:
Aeropyrum camini
NCBI taxonomy Id: 1198449
Other names: A. camini SY1 = JCM 12091, Aeropyrum camini JCM 12091, Aeropyrum camini JCM 12091 = SY1, Aeropyrum camini SY1, Aeropyrum camini SY1 = JCM 12091
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