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BN140_1902 BN140_1902 BN140_3052 BN140_3052 leuB3 leuB3 BN140_3022 BN140_3022 BN140_3006 BN140_3006 gap gap BN140_2589 BN140_2589 BN140_2580 BN140_2580 BN140_2575 BN140_2575 BN140_2574 BN140_2574 ldh ldh BN140_2540 BN140_2540 BN140_2533 BN140_2533 BN140_2531 BN140_2531 BN140_2528 BN140_2528 panE panE hmgA hmgA BN140_2490 BN140_2490 BN140_2446 BN140_2446 BN140_2439 BN140_2439 BN140_2436 BN140_2436 BN140_2400 BN140_2400 BN140_2394 BN140_2394 BN140_2391 BN140_2391 BN140_2377 BN140_2377 acsB acsB acsD acsD BN140_2335 BN140_2335 BN140_2328 BN140_2328 BN140_2320 BN140_2320 BN140_2319 BN140_2319 msrB msrB BN140_2280 BN140_2280 BN140_2264 BN140_2264 cooS cooS BN140_2258 BN140_2258 exaA exaA BN140_2235 BN140_2235 BN140_2230 BN140_2230 BN140_2218 BN140_2218 msrA msrA BN140_2213 BN140_2213 fmdE fmdE fdhA3 fdhA3 fdhB3 fdhB3 BN140_2189 BN140_2189 gapA gapA ldhA ldhA BN140_2168 BN140_2168 rbcL rbcL BN140_2094 BN140_2094 BN140_2092 BN140_2092 BN140_2053 BN140_2053 proG proG aroK1 aroK1 tyrA tyrA aroB aroB BN140_2022 BN140_2022 gltD gltD BN140_1998 BN140_1998 trxA trxA BN140_1941 BN140_1941 ocd ocd BN140_1927 BN140_1927 BN140_1919 BN140_1919 hemA hemA ftrB ftrB folD folD fni fni BN140_0652 BN140_0652 BN140_0676 BN140_0676 porB1 porB1 porA1 porA1 porD1 porD1 porG porG BN140_0718 BN140_0718 sodB sodB hdrA1 hdrA1 guaB guaB hcp hcp BN140_0813 BN140_0813 BN140_0823 BN140_0823 fdhB fdhB fdhA fdhA apbA apbA pyrK pyrK pyrD pyrD mdhA mdhA iorB iorB iorA iorA nadX nadX BN140_0875 BN140_0875 korG korG korA korA korD korD BN140_0910 BN140_0910 BN140_0967 BN140_0967 BN140_1058 BN140_1058 BN140_1067 BN140_1067 BN140_1074 BN140_1074 BN140_1129 BN140_1129 BN140_1141 BN140_1141 asd asd BN140_1146 BN140_1146 dapB dapB BN140_1168 BN140_1168 BN140_1174 BN140_1174 BN140_1182 BN140_1182 BN140_1183 BN140_1183 BN140_1191 BN140_1191 BN140_1196 BN140_1196 ehaJ ehaJ ehaO ehaO BN140_1253 BN140_1253 fwdD1 fwdD1 fwdB1 fwdB1 fwdC1 fwdC1 BN140_1296 BN140_1296 fdhA1 fdhA1 fdhB1 fdhB1 fdhA2 fdhA2 fdhB2 fdhB2 porA3 porA3 porC porC porD3 porD3 BN140_1339 BN140_1339 ilvC ilvC frhA frhA frhG frhG frhB frhB BN140_1390 BN140_1390 egsA egsA BN140_1483 BN140_1483 fwdD3 fwdD3 fwdB3 fwdB3 fwdC3 fwdC3 BN140_1533 BN140_1533 echA echA echE echE echF echF BN140_1541 BN140_1541 BN140_1549 BN140_1549 BN140_1552 BN140_1552 BN140_1564 BN140_1564 BN140_1565 BN140_1565 BN140_1566 BN140_1566 BN140_1569 BN140_1569 BN140_1582 BN140_1582 BN140_1583 BN140_1583 BN140_1594 BN140_1594 cysG cysG BN140_1628 BN140_1628 BN140_1637 BN140_1637 mer mer mtd mtd BN140_1719 BN140_1719 BN140_1724 BN140_1724 BN140_1725 BN140_1725 hdrC hdrC hdrB hdrB hdrA3 hdrA3 MvhD MvhD fwdD5 fwdD5 fwdB5 fwdB5 fwdC5 fwdC5 gabD gabD BN140_1832 BN140_1832 mvhG mvhG mvhA mvhA BN140_1855 BN140_1855 BN140_1864 BN140_1864 BN140_1877 BN140_1877 BN140_0013 BN140_0013 BN140_0014 BN140_0014 argC argC BN140_0082 BN140_0082 wrbA wrbA BN140_0086 BN140_0086 BN140_0089 BN140_0089 BN140_0091 BN140_0091 BN140_0092 BN140_0092 sdhB sdhB sdhA sdhA BN140_0114 BN140_0114 BN140_0117 BN140_0117 BN140_0118 BN140_0118 BN140_0131 BN140_0131 BN140_0143 BN140_0143 BN140_0144 BN140_0144 BN140_0145 BN140_0145 BN140_0214 BN140_0214 nfsA1 nfsA1 nfsA3 nfsA3 BN140_0235 BN140_0235 gltS gltS ribD ribD BN140_0247 BN140_0247 nrdA nrdA BN140_0283 BN140_0283 leuB1 leuB1 nifD1 nifD1 nifD3 nifD3 nifH nifH BN140_0332 BN140_0332 BN140_0338 BN140_0338 BN140_0339 BN140_0339 BN140_0344 BN140_0344 ahpC ahpC BN140_0371 BN140_0371 BN140_0386 BN140_0386 BN140_0387 BN140_0387 BN140_0391 BN140_0391 BN140_0417 BN140_0417 BN140_0424 BN140_0424 BN140_0425 BN140_0425 lpd lpd BN140_0497 BN140_0497 BN140_0499 BN140_0499 BN140_0502 BN140_0502 hisD hisD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BN140_1902Homoserine dehydrogenase, catalytic, Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; High confidence in function and specificity. (329 aa)
BN140_3052Short-chain dehydrogenase/reductase SDR. (246 aa)
leuB33-isopropylmalate dehydrogenase. (322 aa)
BN140_3022Hypothetical protein. (142 aa)
BN140_3006Carboxymuconolactone decarboxylase. (121 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase, type II, C-terminal domain; High confidence in function and specificity. (341 aa)
BN140_2589PBS lyase HEAT-like repeat, Armadillo/beta-catenin-like repeat; Hypothetical protein. (166 aa)
BN140_2580PBS lyase HEAT-like repeat, HEAT repeat; Hypothetical protein. (105 aa)
BN140_2575Glutaredoxin-like domain (DUF836); Hypothetical protein. (90 aa)
BN140_2574Rubredoxin; Ferredoxin thioredoxin reductase catalytic beta chain; High confidence in function and specificity. (170 aa)
ldhLactate/malate dehydrogenase, C-terminal; High confidence in function and specificity. (419 aa)
BN140_2540P-loop ATPase, MinD superfamily; Cobyrinic acid a,c-diamide synthase, Magnesium chelatase, subunit ChlI; High confidence in function and specificity. (289 aa)
BN140_2533Nitrite and sulphite reductase 4Fe-4S domain; High confidence in function and specificity. (284 aa)
BN140_2531Blue (type 1) copper domain, Multicopper oxidase; Hypothetical protein. (135 aa)
BN140_2528Rubredoxin-type Fe(Cys)4 protein; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. (59 aa)
panE2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (314 aa)
hmgAHydroxymethylglutaryl-CoA reductase, class I/II; High confidence in function and specificity; Belongs to the HMG-CoA reductase family. (402 aa)
BN140_2490Oxygen-sensitive ribonucleoside-triphosphate reductase-like protein; Transcription factor S-II (TFIIS), anti_R_Lar: restriction alleviation protein, Lar family; Hypothetical protein. (120 aa)
BN140_2446Protein of unknown function (DUF3157). (198 aa)
BN140_2439Antibiotic biosynthesis monooxygenase. (95 aa)
BN140_2436Hypothetical protein. (69 aa)
BN140_2400Hypothetical protein; FAS1 domain, halocyanin domain; Conserved hypothetical protein. (290 aa)
BN140_2394UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; High confidence in function and specificity; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (457 aa)
BN140_23912-desacetyl-2- hydroxyethylbacteriochlorophyllide; Alcohol dehydrogenase superfamily, zinc-containing, NAD binding domain of 6-phosphogluconate dehydrogenase; High confidence in function and specificity. (713 aa)
BN140_2377Luciferase family protein; Glucose-6-phosphate dehydrogenase-related, F420-dependent, Luciferase-like monooxygenase; High confidence in function and specificity. (330 aa)
acsBBifunctional acetyl-CoA decarbonylase/synthase complex subunit alpha/beta; In acetogenic organisms, this enzyme complex converts carbon dioxide to acetyl-CoA while in methanogenic organisms this enzyme is used to degrade acetyl-CoA to form methane and carbon dioxide; part of an enzyme complex; High confidence in function and specificity. (673 aa)
acsDCO dehydrogenase/acetyl-CoA synthase delta subunit; High confidence in function and specificity. (303 aa)
BN140_2335Rubrerythrin, Domain of unknown function (DUF2383); Hypothetical protein. (151 aa)
BN140_2328Nitroreductase family; Specificity unclear. (185 aa)
BN140_2320PBS lyase HEAT-like repeat, Armadillo/beta-catenin-like repeat; Hypothetical protein. (1180 aa)
BN140_2319NADPH-dependent FMN reductase; Specificity unclear. (223 aa)
msrBPeptide-methionine (R)-S-oxide reductase; This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; High confidence in function and specificity; Belongs to the MsrB Met sulfoxide reductase family. (157 aa)
BN140_2280Glucose/sorbosone dehydrogenases; Sugar (Glycoside-Pentoside-Hexuronide) transporter; High confidence in function and specificity. (588 aa)
BN140_2264Polyferredoxin; 4Fe-4S ferredoxin, iron-sulpur binding domain; Conserved hypothetical protein. (261 aa)
cooSCarbon-monoxide dehydrogenase, catalytic subunit, Prismane/CO dehydrogenase family; High confidence in function and specificity. (636 aa)
BN140_2258Blue (type 1) copper domain, Domain of unknown function (DUF1735); Hypothetical protein. (270 aa)
exaAQuinoprotein ethanol dehydrogenase; High confidence in function and specificity. (815 aa)
BN140_2235Nitroreductase family; Conserved hypothetical protein. (224 aa)
BN140_2230Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; Conserved hypothetical protein. (134 aa)
BN140_2218Protein of unknown function DUF2148; High confidence in function and specificity. (212 aa)
msrAPeptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (159 aa)
BN140_2213Amine oxidase, Flavin containing amine oxidoreductase; High confidence in function and specificity. (447 aa)
fmdEFormylmethanofuran dehydrogenase, subunit E domain, TFIIB zinc-binding; High confidence in function and specificity. (213 aa)
fdhA3Formate dehydrogenase, alpha subunit, Molybdopterin oxidoreductase; High confidence in function and specificity. (689 aa)
fdhB3Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal, N-term; High confidence in function and specificity. (412 aa)
BN140_2189Short-chain dehydrogenase/reductase SDR; High confidence in function and specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (282 aa)
gapAGlyceraldehyde/Erythrose phosphate dehydrogenase family, Oxidoreductase family, NAD-binding Rossmann fold; High confidence in function and specificity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
ldhAD-lactate dehydrogenase; NADP oxidoreductase coenzyme F420-dependent; High confidence in function and specificity; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (352 aa)
BN140_2168Rubrerythrin. (151 aa)
rbcLRibulose bisophosphate carboxylase; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (430 aa)
BN140_2094UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Nucleotide sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; High confidence in function and specificity; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (504 aa)
BN140_2092Hypothetical protein. (118 aa)
BN140_2053Rubredoxin-type Fe(Cys)4 protein, Transcription elongation factor Elf1 like; High confidence in function and specificity; Belongs to the rubredoxin family. (128 aa)
proGCompetence protein ComER; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (266 aa)
aroK1Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (451 aa)
tyrAPrephenate dehydrogenase, NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; High confidence in function and specificity. (274 aa)
aroBDehydroquinate synthase II; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. (328 aa)
BN140_2022ferredoxin-NADP+ reductase; Cytochrome-c3 hydrogenase, gamma subunit, Oxidoreductase FAD-binding domain; High confidence in function and specificity. (286 aa)
gltDGlutamate synthase (NADPH/NADH) small chain; 1.4.1.14], Glutamate synthase (NADPH), homotetrameric, Nitrogenase component 1 type Oxidoreductase; High confidence in function and specificity. (447 aa)
BN140_1998Rubredoxin-type Fe(Cys)4 protein, HIT zinc finger; Hypothetical protein; Belongs to the rubredoxin family. (116 aa)
trxAThioredoxin-like; Conserved hypothetical protein. (95 aa)
BN140_1941NADPH-dependent F420 reductase. (216 aa)
ocdOrnithine cyclodeaminase; Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate; Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily. (312 aa)
BN140_1927Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain, Protein of unknown function (DUF447); Conserved hypothetical protein. (134 aa)
BN140_1919NADPH-dependent FMN reductase. (293 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (423 aa)
ftrBFerredoxin thioredoxin reductase, beta subunit; High confidence in function and specificity. (93 aa)
folDMethylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (283 aa)
fniIsopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (350 aa)
BN140_0652PBS lyase HEAT-like repeat; Hypothetical protein. (525 aa)
BN140_0676Amine oxidase, Flavin containing amine oxidoreductase; Hypothetical protein. (410 aa)
porB1Pyruvate ferredoxin oxidoreductase, beta subunit; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; High confidence in function and specificity. (303 aa)
porA1Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal, Transketolase, C-terminal domain, I; High confidence in function and specificity. (384 aa)
porD12-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate; High confidence in function and specificity. (86 aa)
porG2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; High confidence in function and specificity. (181 aa)
BN140_0718Hypothetical protein; Putative methanogenesis marker 13 metalloprotein, Nitrogenase component 1 type Oxidoreductase; High confidence in function and specificity. (354 aa)
sodBSuperoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (213 aa)
hdrA1Heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (424 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (488 aa)
hcpHydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (538 aa)
BN140_0813UDP-N-acetylglucosamine 4,6-dehydratase (inverting); Polysaccharide biosynthesis protein CapD-like; High confidence in function and specificity. (295 aa)
BN140_0823UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Nucleotide sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; High confidence in function and specificity; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (476 aa)
fdhBCoenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal, N-term; High confidence in function and specificity. (422 aa)
fdhAFormate dehydrogenase, alpha subunit, Molybdopterin oxidoreductase; High confidence in function and specificity. (687 aa)
apbA2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (305 aa)
pyrKCytochrome-c3 hydrogenase, gamma subunit, Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; High confidence in function and specificity. (254 aa)
pyrDDihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. (295 aa)
mdhAL-lactate/malate dehydrogenase, lactate/malate dehydrogenase, NAD binding domain; High confidence in function and specificity; Belongs to the LDH/MDH superfamily. (288 aa)
iorBIndolepyruvate ferredoxin oxidoreductase, beta subunit; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain, Pyruvate ferredoxin/flavodoxin oxidoreductase; High confidence in function and specificity. (199 aa)
iorAIndolepyruvate ferredoxin oxidoreductase, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (589 aa)
nadXAspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. (252 aa)
BN140_0875PBS lyase HEAT-like repeat; Hypothetical protein. (180 aa)
korG2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; High confidence in function and specificity. (176 aa)
korA2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal, domain; High confidence in function and specificity. (360 aa)
korD2-oxoglutarate ferredoxin oxidoreductase subunit delta; 4Fe-4S ferredoxin, iron-sulpur binding domain, putative zinc ribbon domain; High confidence in function and specificity. (90 aa)
BN140_0910Nitroreductase-like, Extracellular link domain; High confidence in function and specificity. (175 aa)
BN140_0967Arylsulfatase regulator (Fe-S oxidoreductase); Conserved hypothetical protein CHP04083, radical SAM, Radical SAM superfamily; High confidence in function and specificity. (385 aa)
BN140_1058Iron-sulfur flavoprotein; High confidence in function and specificity. (277 aa)
BN140_1067Nitrite/sulphite reductase 4Fe-4S domain; Specificity unclear. (293 aa)
BN140_1074NADH dehydrogenase/NAD(P)H nitroreductase; Nitroreductase-like, Nitroreductase family; Specificity unclear. (176 aa)
BN140_1129Hypothetical protein; Oxidoreductase, molybdopterin-binding domain. (189 aa)
BN140_1141Glucose-6-phosphate dehydrogenase (coenzyme-F420). (319 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the formation of aspartate semialdehyde from aspartyl phosphate; High confidence in function and specificity. (338 aa)
BN140_11464Fe-4S ferredoxin, iron-sulpur binding domain; Hypothetical protein. (31 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (252 aa)
BN140_11684Fe-4S ferredoxin, iron-sulpur binding domain; Hypothetical protein. (75 aa)
BN140_11744Fe-4S ferredoxin, iron-sulpur binding domain; Hypothetical protein. (87 aa)
BN140_1182Hypothetical protein; Rubrerythrin. (104 aa)
BN140_1183NADPH-dependent FMN reductase, PX domain; Specificity unclear. (222 aa)
BN140_11915-amino-6-(5- phosphoribosylamino)uracilreductase; Riboflavin-specific deaminase, C-terminal, RibD C-terminal domain; High confidence in function and specificity. (232 aa)
BN140_1196Geranylgeranyl reductase; Monooxygenase, FAD-binding, FAD binding domain; High confidence in function and specificity. (343 aa)
ehaJMembrane-bound hydrogenase subunit ehaJ; Putative NADH-ubiquinone oxidoreductase MJ0520; High confidence in function and specificity. (281 aa)
ehaONADH-quinone oxidoreductase, subunit D, Respiratory-chain NADH dehydrogenase, 49 Kd subunit; High confidence in function and specificity. (362 aa)
BN140_1253Formylmethanofuran dehydrogenase; 4Fe-4S ferredoxin, iron-sulpur binding domain; High confidence in function and specificity. (201 aa)
fwdD1Formylmethanofuran dehydrogenase, subunit D, Molydopterin dinucleotide binding domain; High confidence in function and specificity. (129 aa)
fwdB1Formylmethanofuran dehydrogenase, subunit B, Molybdopterin oxidoreductase; High confidence in function and specificity. (429 aa)
fwdC1Formylmethanofuran dehydrogenase subunit C, Septum formation inhibitor MinC, C-terminal domain; High confidence in function and specificity. (256 aa)
BN140_1296Alkylhydroperoxidase; Carboxymuconolactone decarboxylase family; Hypothetical protein. (139 aa)
fdhA1Formate dehydrogenase, alpha subunit, Molybdopterin oxidoreductase; High confidence in function and specificity. (688 aa)
fdhB1Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; High confidence in function and specificity. (383 aa)
fdhA2Formate dehydrogenase, alpha subunit, Molybdopterin oxidoreductase; High confidence in function and specificity. (688 aa)
fdhB2Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal, N-term; High confidence in function and specificity. (412 aa)
porA3Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal, 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; High confidence in function and specificity. (370 aa)
porC2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; High confidence in function and specificity. (175 aa)
porD32-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate; High confidence in function and specificity. (81 aa)
BN140_1339Peroxiredoxin, OsmC-like protein; Hypothetical protein. (175 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (329 aa)
frhACoenzyme F420 hydrogenase, subunit alpha, Nickel-dependent hydrogenase; High confidence in function and specificity; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (455 aa)
frhGCoenzyme F420 hydrogenase, subunit gamma, PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family; High confidence in function and specificity. (253 aa)
frhBCoenzyme F420 hydrogenase, subunit beta, Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus; High confidence in function and specificity. (295 aa)
BN140_1390Flavin reductase-like protein; Flavin reductase like domain; High confidence in function and specificity. (194 aa)
egsANAD(P)-dependent glycerol-1-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family. (360 aa)
BN140_1483NADPH-dependent FMN reductase; Specificity unclear. (174 aa)
fwdD3Formylmethanofuran dehydrogenase subunit D; Molydopterin dinucleotide binding domain; High confidence in function and specificity. (113 aa)
fwdB3Formylmethanofuran dehydrogenase, subunit B, Molybdopterin oxidoreductase; High confidence in function and specificity. (455 aa)
fwdC3Formylmethanofuran dehydrogenase subunit C; High confidence in function and specificity. (266 aa)
BN140_1533Hypothetical protein; Domain of unknown function (DUF362); High confidence in function and specificity. (392 aa)
echANADH dehydrogenase (quinone); NADH:ubiquinone/plastoquinone oxidoreductase; High confidence in function and specificity. (633 aa)
echENADH-ubiquinone oxidoreductase chain 49kDa; NADH-quinone oxidoreductase, subunit D, Nickel-dependent hydrogenase; High confidence in function and specificity. (359 aa)
echFFormate hydrogenlyase; 4Fe-4S ferredoxin, iron-sulpur binding domain; Hypothetical protein. (132 aa)
BN140_1541Glutathione-disulphide reductase-related, Pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (456 aa)
BN140_1549Radical SAM superfamily; Hypothetical protein. (372 aa)
BN140_1552Flavoredoxin; Flavin reductase-like, FMN-binding; High confidence in function and specificity. (211 aa)
BN140_1564Glutamate synthase (NADPH/NADH) large chain; 1.4.1.14], Glutamate synthase, central-C, Conserved region in glutamate synthase; High confidence in function and specificity; Belongs to the glutamate synthase family. (505 aa)
BN140_1565Glutamate synthase, large subunit domain 3 stand-alone protein; High confidence in function and specificity. (245 aa)
BN140_1566Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; High confidence in function and specificity. (339 aa)
BN140_1569Rubredoxin-type Fe(Cys)4 protein; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. (65 aa)
BN140_1582Geranylgeranyl reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. (398 aa)
BN140_15834Fe-4S ferredoxin, iron-sulpur binding domain; Hypothetical protein. (79 aa)
BN140_1594Short-chain dehydrogenase/reductase SDR, KR domain; Specificity unclear; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (278 aa)
cysGPrecorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; 4.99.1.4], Sirohaem synthase, N-terminal, Saccharopine dehydrogenase; High confidence in function and specificity. (208 aa)
BN140_1628Alkylhydroperoxidase; Carboxymuconolactone decarboxylase; High confidence in function and specificity. (148 aa)
BN140_1637Aldo/keto reductase family; High confidence in function and specificity. (282 aa)
merCoenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. (330 aa)
mtdMethylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. (280 aa)
BN140_1719Ferredoxin oxidoreductase subunit alpha;, Thiamine pyrophosphate enzyme, C-terminal TPP-binding; High confidence in function and specificity. (423 aa)
BN140_1724Hypothetical protein; 4Fe-4S ferredoxin, iron-sulpur binding domain; High confidence in function and specificity. (90 aa)
BN140_1725Hypothetical protein; Formylmethanofuran dehydrogenase, subunit F, Pre-mRNA splicing factor PRP21 like protein; High confidence in function and specificity. (389 aa)
hdrCCoB-CoM heterodisulphide reductase, subunit C, 4Fe-4S binding domain; High confidence in function and specificity. (193 aa)
hdrBCoB-CoM heterodisulphide reductase, subunit B; High confidence in function and specificity. (299 aa)
hdrA3Heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (674 aa)
MvhDMethyl-viologen-reducing hydrogenase, delta subunit; High confidence in function and specificity. (141 aa)
fwdD5Formylmethanofuran dehydrogenase, subunit D, Molydopterin dinucleotide binding domain; High confidence in function and specificity. (133 aa)
fwdB5Formylmethanofuran dehydrogenase, subunit B, Molybdopterin oxidoreductase; High confidence in function and specificity. (437 aa)
fwdC5Formylmethanofuran dehydrogenase subunit C; High confidence in function and specificity. (268 aa)
gabDSuccinate-semialdehyde dehydrogenase (NADP+); Aldehyde dehydrogenase domain, Aldehyde dehydrogenase family; High confidence in function and specificity. (477 aa)
BN140_18324Fe-4S ferredoxin, iron-sulpur binding domain, 4Fe-4S binding domain; Hypothetical protein. (80 aa)
mvhGCoenzyme F420-non-reducing hydrogenase (methyl viologen-reducing hydrogenase), gamma subunit; [NiFe]-hydrogenase-3-type complex, small subunit/NADH:quinone oxidoreductase, subunit NuoB, NADH ubiquinone oxidoreductase, 20 Kd subunit; High confidence in function and specificity. (306 aa)
mvhANickel-dependent hydrogenase, large subunit; High confidence in function and specificity; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (454 aa)
BN140_1855NADH-plastoquinone oxidoreductase; 4Fe-4S ferredoxin, iron-sulpur binding domain, NIL domain; Hypothetical protein. (132 aa)
BN140_1864PBS lyase HEAT-like repeat, Armadillo/beta-catenin-like repeat; Hypothetical protein. (1349 aa)
BN140_1877ATPase RIL; ABC transporter-like; High confidence in function and specificity. (590 aa)
BN140_0013Redox-active disulfide protein 2; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro. (80 aa)
BN140_0014Small redox-active disulfide protein 2; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro. (89 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (328 aa)
BN140_0082NADPH-dependent FMN reductase. (208 aa)
wrbANADPH-dependent FMN reductase. (203 aa)
BN140_0086Peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (214 aa)
BN140_0089NADPH-dependent FMN reductase. (202 aa)
BN140_0091Rubrerythrin; Nonheme iron binding domain containing a [Fe(SCys)4] center; Hypothetical protein. (216 aa)
BN140_0092Glutaredoxin. (393 aa)
sdhBSuccinate dehydrogenase and fumarate reductase iron-sulfur protein; Hypothetical protein. (487 aa)
sdhA1.3.99.1, Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex; Hypothetical protein. (554 aa)
BN140_0114Thioredoxin domain; Hypothetical protein. (138 aa)
BN140_0117NADPH-dependent FMN reductase. (188 aa)
BN140_01184Fe-4S ferredoxin, iron-sulfur binding domain protein; Hypothetical protein. (367 aa)
BN140_0131Rubredoxin-type Fe(Cys)4 protein; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. (52 aa)
BN140_0143Hypothetical protein; Pyridoxamine 5'-phosphate oxidase. (159 aa)
BN140_0144Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; Hypothetical protein. (163 aa)
BN140_0145Fe-S oxidoreductase; Cysteine-rich domain; Hypothetical protein. (362 aa)
BN140_0214Geranylgeranyl reductase, Glucose inhibited division protein A; Specificity unclear. (403 aa)
nfsA1Nitroreductase-like; High confidence in function and specificity. (246 aa)
nfsA3Nitroreductase family; High confidence in function and specificity. (246 aa)
BN140_02352-oxoacid:acceptor oxidoreductase, alpha subunit, Pyruvate ferredoxin/flavodoxin oxidoreductase; High confidence in function and specificity. (604 aa)
gltSGlutamate synthase, central-C, Conserved region in glutamate synthase; High confidence in function and specificity. (529 aa)
ribD5-amino-6-(5- phosphoribosylamino)uracilreductase; 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; High confidence in function and specificity. (226 aa)
BN140_0247Archaeoflavoprotein; 4Fe-4S ferredoxin, iron-sulpur binding domain; Specificity unclear. (57 aa)
nrdARibonucleoside-diphosphate reductase alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (548 aa)
BN140_0283Thioredoxin domain, KaiB domain; Hypothetical protein. (160 aa)
leuB13-isopropylmalate dehydrogenase; High confidence in function and specificity. (373 aa)
nifD1Nitrogenase/oxidoreductase, component 1; Hypothetical protein. (386 aa)
nifD3Nitrogenase molybdenum-iron protein; Nitrogenase/oxidoreductase, component 1, Nitrogenase component 1 type Oxidoreductase; High confidence in function and specificity; Belongs to the NifD/NifK/NifE/NifN family. (347 aa)
nifHNitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL; High confidence in function and specificity; Belongs to the NifH/BchL/ChlL family. (272 aa)
BN140_0332Flavoprotein; Rubredoxin-oxygen oxidoreductase, Flavodoxin; High confidence in function and specificity. (396 aa)
BN140_0338Glutaredoxin. (109 aa)
BN140_0339Ribonucleoside-triphosphate reductase; Intein DOD homing endonuclease, ATP cone domain; High confidence in function and specificity. (1668 aa)
BN140_0344PBS lyase HEAT domain-containing protein; Armadillo, HEAT repeat; Hypothetical protein. (962 aa)
ahpCPeroxiredoxin Q/BCP; AhpC/TSA family; High confidence in function and specificity. (154 aa)
BN140_0371Hypothetical protein; 4Fe-4S ferredoxin, iron-sulpur binding domain. (218 aa)
BN140_0386PBS lyase HEAT-like repeat; Hypothetical protein. (91 aa)
BN140_0387PBS lyase HEAT-like repeat; Hypothetical protein. (89 aa)
BN140_0391Metallo-beta-lactamase/flavodoxin domain-containing protein; Rubredoxin-oxygen oxidoreductase, Flavodoxin; High confidence in function and specificity. (404 aa)
BN140_0417Iron-sulfur cluster-binding protein; 4Fe-4S ferredoxin, iron-sulpur binding domain; Hypothetical protein. (260 aa)
BN140_0424Hypothetical protein; NADPH-dependent FMN reductase. (112 aa)
BN140_0425Hypothetical protein. (70 aa)
lpdDihydrolipoamide dehydrogenase; Pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity. (441 aa)
BN140_0497Hypothetical protein; YHS. (49 aa)
BN140_0499PBS lyase HEAT-like repeat, HEAT repeat; Hypothetical protein. (287 aa)
BN140_0502PBS lyase HEAT-like repeat; Hypothetical protein. (345 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (416 aa)
Your Current Organism:
Methanoculleus bourgensis
NCBI taxonomy Id: 1201294
Other names: M. bourgensis MS2, Methanoculleus bourgensis DSM 3045, Methanoculleus bourgensis MS2
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