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dadD dadD fwdA1 fwdA1 adeC adeC fwdA3 fwdA3 fwdA5 fwdA5 pyrC pyrC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
dadDHydrolase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety [...] (434 aa)
fwdA1Formylmethanofuran dehydrogenase, subunit A; High confidence in function and specificity. (566 aa)
adeCAdenine deaminase, Amidohydrolase family; High confidence in function and specificity; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (523 aa)
fwdA3Formylmethanofuran dehydrogenase, subunit A, Amidohydrolase family; High confidence in function and specificity. (570 aa)
fwdA5Formylmethanofuran dehydrogenase, subunit A, Amidohydrolase family; High confidence in function and specificity. (569 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (420 aa)
Your Current Organism:
Methanoculleus bourgensis
NCBI taxonomy Id: 1201294
Other names: M. bourgensis MS2, Methanoculleus bourgensis DSM 3045, Methanoculleus bourgensis MS2
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