Your Input: | |
| | BN140_0034 | acetate-CoA ligase. (629 aa) |
| | sdhB | Succinate dehydrogenase and fumarate reductase iron-sulfur protein; Hypothetical protein. (487 aa) |
| | sdhA | 1.3.99.1, Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex; Hypothetical protein. (554 aa) |
| | nadB | Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; Hypothetical protein; Belongs to the aspartokinase family. (462 aa) |
| | arcC | Carbamate kinase; Catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; Hypothetical protein; Belongs to the carbamate kinase family. (314 aa) |
| | mch1 | Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family. (314 aa) |
| | prsA | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (285 aa) |
| | pgk1 | Phosphoglycerate kinase; High confidence in function and specificity; Belongs to the phosphoglycerate kinase family. (404 aa) |
| | cofH1 | FO synthase, subunit 2-like, Radical SAM superfamily; High confidence in function and specificity. (362 aa) |
| | BN140_0234 | 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; High confidence in function and specificity. (294 aa) |
| | BN140_0235 | 2-oxoacid:acceptor oxidoreductase, alpha subunit, Pyruvate ferredoxin/flavodoxin oxidoreductase; High confidence in function and specificity. (604 aa) |
| | nifH | Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL; High confidence in function and specificity; Belongs to the NifH/BchL/ChlL family. (272 aa) |
| | prk | Phosphoribulokinase/uridine kinase, Type II/IV secretion system protein; High confidence in function and specificity. (327 aa) |
| | apgM | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (411 aa) |
| | BN140_0431 | 5'-Nucleotidase/apyrase, 5'-nucleotidase, C-terminal domain; High confidence in function and specificity. (479 aa) |
| | gpi1 | Glucose-6-phosphate isomerase, prokaryote; High confidence in function and specificity. (240 aa) |
| | lpd | Dihydrolipoamide dehydrogenase; Pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity. (441 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (430 aa) |
| | argD | acetylornithine/N- succinyldiaminopimelateaminotransferase; 2.6.1.17], Acetylornithine/Succinylornithine aminotransferase, Aminotransferase class-III; High confidence in function and specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (374 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase, D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; High confidence in function and specificity. (527 aa) |
| | ppsA1 | Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (768 aa) |
| | cofG | FO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. (328 aa) |
| | cofC | Hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (215 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (283 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (423 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (561 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (395 aa) |
| | thrC3 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (400 aa) |
| | porB1 | Pyruvate ferredoxin oxidoreductase, beta subunit; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; High confidence in function and specificity. (303 aa) |
| | porA1 | Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal, Transketolase, C-terminal domain, I; High confidence in function and specificity. (384 aa) |
| | porD1 | 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate; High confidence in function and specificity. (86 aa) |
| | porG | 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; High confidence in function and specificity. (181 aa) |
| | hps | 6-phospho-3-hexuloisomerase; 6-phospho 3-hexuloisomerase, SIS domain; High confidence in function and specificity. (205 aa) |
| | cobB | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. (456 aa) |
| | BN140_0718 | Hypothetical protein; Putative methanogenesis marker 13 metalloprotein, Nitrogenase component 1 type Oxidoreductase; High confidence in function and specificity. (354 aa) |
| | BN140_0719 | Hypothetical protein; Uroporphyrinogen-III synthase HemD; High confidence in function and specificity. (386 aa) |
| | cbiX | Sirohydrochlorin cobaltochelatase; Cobalamin (vitamin B12) biosynthesis CbiX, Ferrochelatase; High confidence in function and specificity. (130 aa) |
| | hdrA1 | Heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (424 aa) |
| | fdhB | Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal, N-term; High confidence in function and specificity. (422 aa) |
| | fdhA | Formate dehydrogenase, alpha subunit, Molybdopterin oxidoreductase; High confidence in function and specificity. (687 aa) |
| | mdhA | L-lactate/malate dehydrogenase, lactate/malate dehydrogenase, NAD binding domain; High confidence in function and specificity; Belongs to the LDH/MDH superfamily. (288 aa) |
| | sucD | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (288 aa) |
| | sucC | Succinyl-CoA synthetase, beta subunit, ATP-grasp domain; High confidence in function and specificity. (361 aa) |
| | korG | 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; High confidence in function and specificity. (176 aa) |
| | korB | 2-oxoglutarate ferredoxin oxidoreductase subunit beta; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; High confidence in function and specificity. (262 aa) |
| | korA | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal, domain; High confidence in function and specificity. (360 aa) |
| | korD | 2-oxoglutarate ferredoxin oxidoreductase subunit delta; 4Fe-4S ferredoxin, iron-sulpur binding domain, putative zinc ribbon domain; High confidence in function and specificity. (90 aa) |
| | fumB | Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain, Fumarase C-terminus; High confidence in function and specificity. (180 aa) |
| | fumA | Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain, Fumarate hydratase (Fumerase); High confidence in function and specificity. (279 aa) |
| | BN140_0978 | 3-hydroxypropionyl-CoA synthase; AMP-dependent synthetase/ligase, AMP-binding enzyme; High confidence in function and specificity. (577 aa) |
| | BN140_1067 | Nitrite/sulphite reductase 4Fe-4S domain; Specificity unclear. (293 aa) |
| | fae-hps | 3-hexulose-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family. (393 aa) |
| | manB | Phosphoglucomutase/phosphomannomutase; 5.4.2.8, This archaeal PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates; Hypothetical protein. (453 aa) |
| | acyP | Acylphosphatase. (95 aa) |
| | paaK | Coenzyme F390 synthetase; Putative phenylacetate-CoA ligase; Hypothetical protein. (429 aa) |
| | paaK2 | Coenzyme F390 synthetase; Putative phenylacetate-CoA ligase; Hypothetical protein. (433 aa) |
| | BN140_1140 | 3-hexulose-6-phosphate synthase. (429 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the formation of aspartate semialdehyde from aspartyl phosphate; High confidence in function and specificity. (338 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (252 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa) |
| | argE | Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase; High confidence in function and specificity. (389 aa) |
| | BN140_1177 | 6-phospho-3-hexuloisomerase; 6-phospho 3-hexuloisomerase, SIS domain; High confidence in function and specificity. (199 aa) |
| | mttC | 5-methyltetrahydrofolate- homocysteinemethyltransferase; B12 binding domain; High confidence in function and specificity. (225 aa) |
| | fwdD1 | Formylmethanofuran dehydrogenase, subunit D, Molydopterin dinucleotide binding domain; High confidence in function and specificity. (129 aa) |
| | fwdB1 | Formylmethanofuran dehydrogenase, subunit B, Molybdopterin oxidoreductase; High confidence in function and specificity. (429 aa) |
| | fwdA1 | Formylmethanofuran dehydrogenase, subunit A; High confidence in function and specificity. (566 aa) |
| | fwdC1 | Formylmethanofuran dehydrogenase subunit C, Septum formation inhibitor MinC, C-terminal domain; High confidence in function and specificity. (256 aa) |
| | BN140_1296 | Alkylhydroperoxidase; Carboxymuconolactone decarboxylase family; Hypothetical protein. (139 aa) |
| | fbpA | Fructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (365 aa) |
| | BN140_1312 | acetate-CoA ligase. (632 aa) |
| | rpiA | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (232 aa) |
| | fdhA1 | Formate dehydrogenase, alpha subunit, Molybdopterin oxidoreductase; High confidence in function and specificity. (688 aa) |
| | fdhB1 | Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; High confidence in function and specificity. (383 aa) |
| | fdhA2 | Formate dehydrogenase, alpha subunit, Molybdopterin oxidoreductase; High confidence in function and specificity. (688 aa) |
| | fdhB2 | Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal, N-term; High confidence in function and specificity. (412 aa) |
| | porB3 | Pyruvate ferredoxin oxidoreductase, beta subunit; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; High confidence in function and specificity. (317 aa) |
| | porA3 | Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal, 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; High confidence in function and specificity. (370 aa) |
| | porC | 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; High confidence in function and specificity. (175 aa) |
| | porD3 | 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate; High confidence in function and specificity. (81 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (181 aa) |
| | cofD1 | LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052, Uncharacterised protein family UPF0052; High confidence in function and specificity. (301 aa) |
| | cofD2 | LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. (301 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine. (272 aa) |
| | frhA | Coenzyme F420 hydrogenase, subunit alpha, Nickel-dependent hydrogenase; High confidence in function and specificity; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (455 aa) |
| | frhD1 | Peptidase A31, coenzyme F420-reducing hydrogenase delta subunit, Hydrogenase maturation protease; High confidence in function and specificity. (183 aa) |
| | frhG | Coenzyme F420 hydrogenase, subunit gamma, PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family; High confidence in function and specificity. (253 aa) |
| | frhB | Coenzyme F420 hydrogenase, subunit beta, Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus; High confidence in function and specificity. (295 aa) |
| | ppcA | Phosphoenolpyruvate carboxylase; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. (485 aa) |
| | cofH3 | 7, 8-didemethyl-8-hydroxy-5-deazariboflavinsynthase; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. (376 aa) |
| | mcrA1 | Methyl-coenzyme M reductase alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (568 aa) |
| | mcrG1 | Methyl-coenzyme M reductase, gamma subunit; High confidence in function and specificity. (254 aa) |
| | mcrD1 | Methyl-coenzyme M reductase operon protein D; Specificity unclear. (199 aa) |
| | mcrB1 | Methyl-coenzyme M reductase, beta subunit; High confidence in function and specificity. (434 aa) |
| | fwdD3 | Formylmethanofuran dehydrogenase subunit D; Molydopterin dinucleotide binding domain; High confidence in function and specificity. (113 aa) |
| | fwdB3 | Formylmethanofuran dehydrogenase, subunit B, Molybdopterin oxidoreductase; High confidence in function and specificity. (455 aa) |
| | fwdA3 | Formylmethanofuran dehydrogenase, subunit A, Amidohydrolase family; High confidence in function and specificity. (570 aa) |
| | fwdC3 | Formylmethanofuran dehydrogenase subunit C; High confidence in function and specificity. (266 aa) |
| | glnA1 | Glutamine synthetase, catalytic domain; High confidence in function and specificity. (443 aa) |
| | BN140_1566 | Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; High confidence in function and specificity. (339 aa) |
| | BN140_1621 | ABC transporter ATP-binding protein; Methyl coenzyme M reductase system, component A2, IstB-like ATP binding protein; High confidence in function and specificity. (536 aa) |
| | hemD | Tetrapyrrole biosynthesis, uroporphyrinogen III synthase, Uroporphyrinogen-III synthase HemD; High confidence in function and specificity. (226 aa) |
| | mer | Coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. (330 aa) |
| | mtd | Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. (280 aa) |
| | leuD3 | 4.2.1.35], 3-isopropylmalate dehydratase, small subunit, subgroup, Aconitate hydratase 2 N-terminus; High confidence in function and specificity. (157 aa) |
| | leuC3 | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (403 aa) |
| | aksA | 2-isopropylmalate synthase; Pyruvate carboxyltransferase; High confidence in function and specificity; Belongs to the alpha-IPM synthase/homocitrate synthase family. (376 aa) |
| | ftr | Formylmethanofuran-tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family. (302 aa) |
| | BN140_1724 | Hypothetical protein; 4Fe-4S ferredoxin, iron-sulpur binding domain; High confidence in function and specificity. (90 aa) |
| | BN140_1725 | Hypothetical protein; Formylmethanofuran dehydrogenase, subunit F, Pre-mRNA splicing factor PRP21 like protein; High confidence in function and specificity. (389 aa) |
| | hdrC | CoB-CoM heterodisulphide reductase, subunit C, 4Fe-4S binding domain; High confidence in function and specificity. (193 aa) |
| | hdrB | CoB-CoM heterodisulphide reductase, subunit B; High confidence in function and specificity. (299 aa) |
| | hdrA3 | Heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (674 aa) |
| | MvhD | Methyl-viologen-reducing hydrogenase, delta subunit; High confidence in function and specificity. (141 aa) |
| | fwdD5 | Formylmethanofuran dehydrogenase, subunit D, Molydopterin dinucleotide binding domain; High confidence in function and specificity. (133 aa) |
| | fwdB5 | Formylmethanofuran dehydrogenase, subunit B, Molybdopterin oxidoreductase; High confidence in function and specificity. (437 aa) |
| | fwdA5 | Formylmethanofuran dehydrogenase, subunit A, Amidohydrolase family; High confidence in function and specificity. (569 aa) |
| | fwdC5 | Formylmethanofuran dehydrogenase subunit C; High confidence in function and specificity. (268 aa) |
| | mcrB3 | Ulfoethylthiotransferase beta, Methyl-coenzyme M reductase, beta subunit; High confidence in function and specificity. (434 aa) |
| | mcrD3 | Methyl-coenzyme M reductase, protein D; Specificity unclear. (158 aa) |
| | mcrC | Methyl-coenzyme M reductase operon protein C; High confidence in function and specificity. (207 aa) |
| | mcrG3 | Sulfoethylthiotransferase gamma;, Methyl-coenzyme M reductase, gamma subunit; High confidence in function and specificity. (253 aa) |
| | mcrA3 | Methyl-coenzyme M reductase alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (568 aa) |
| | mtrE | Tetrahydromethanopterin S-methyltransferase subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (299 aa) |
| | mtrD | Tetrahydromethanopterin S-methyltransferase subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (283 aa) |
| | mtrC | Tetrahydromethanopterin S-methyltransferase subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (283 aa) |
| | mtrB | Tetrahydromethanopterin S-methyltransferase subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (94 aa) |
| | mtrA1 | Tetrahydromethanopterin S-methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (241 aa) |
| | mtrF | Tetrahydromethanopterin S-methyltransferase, F subunit; Specificity unclear. (70 aa) |
| | mtrA2 | Tetrahydromethanopterin S-methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (246 aa) |
| | mtrH | Tetrahydromethanopterin S-methyltransferase, MtrH subunit; High confidence in function and specificity. (345 aa) |
| | mch3 | Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family. (315 aa) |
| | BN140_1814 | Bisphosphoglycerate-independent phosphoglycerate mutase; High confidence in function and specificity. (408 aa) |
| | BN140_1824 | F420-0:gamma-glutamyl ligase; High confidence in function and specificity. (249 aa) |
| | mvhG | Coenzyme F420-non-reducing hydrogenase (methyl viologen-reducing hydrogenase), gamma subunit; [NiFe]-hydrogenase-3-type complex, small subunit/NADH:quinone oxidoreductase, subunit NuoB, NADH ubiquinone oxidoreductase, 20 Kd subunit; High confidence in function and specificity. (306 aa) |
| | mvhA | Nickel-dependent hydrogenase, large subunit; High confidence in function and specificity; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (454 aa) |
| | BN140_1902 | Homoserine dehydrogenase, catalytic, Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; High confidence in function and specificity. (329 aa) |
| | BN140_1906 | Formaldehyde-activating enzyme; High confidence in function and specificity. (167 aa) |
| | cysG | Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; 4.99.1.4], Sirohaem synthase, N-terminal, Saccharopine dehydrogenase; High confidence in function and specificity. (208 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (423 aa) |
| | hemB | Tetrapyrrole biosynthesis, porphobilinogen synthase, Delta-aminolevulinic acid dehydratase; High confidence in function and specificity; Belongs to the ALAD family. (327 aa) |
| | hemL | Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; High confidence in function and specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (415 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapyrrole biosynthesis, hydroxymethylbilane synthase, Bacterial extracellular solute-binding proteins, family 3; High confidence in function and specificity. (294 aa) |
| | hemX | Uroporphyrin-III C-methyltransferase, C-terminal; High confidence in function and specificity; Belongs to the precorrin methyltransferase family. (266 aa) |
| | BN140_1940 | Class II aldolase/adducin, N-terminal; High confidence in function and specificity. (180 aa) |
| | pycB | Oxaloacetate decarboxylase, alpha subunit, Conserved carboxylase domain; High confidence in function and specificity. (582 aa) |
| | pycA | Pyruvate carboxylase subunit A; Biotin carboxylation domain, Carbamoyl-phosphate synthase L chain, N-terminal domain; High confidence in function and specificity. (491 aa) |
| | gltD | Glutamate synthase (NADPH/NADH) small chain; 1.4.1.14], Glutamate synthase (NADPH), homotetrameric, Nitrogenase component 1 type Oxidoreductase; High confidence in function and specificity. (447 aa) |
| | tpiA | Triosephosphate isomerase (TIM); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (222 aa) |
| | fbaA1 | Fructose-bisphosphate aldolase, class I; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (263 aa) |
| | fbaA3 | Fructose-bisphosphate aldolase, class I; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (260 aa) |
| | gpi3 | Glucose-6-phosphate isomerase, prokaryote; High confidence in function and specificity. (232 aa) |
| | rbcL | Ribulose bisophosphate carboxylase; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (430 aa) |
| | ppsA3 | Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (812 aa) |
| | ldhA | D-lactate dehydrogenase; NADP oxidoreductase coenzyme F420-dependent; High confidence in function and specificity; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (352 aa) |
| | gapA | Glyceraldehyde/Erythrose phosphate dehydrogenase family, Oxidoreductase family, NAD-binding Rossmann fold; High confidence in function and specificity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | gpmA | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa) |
| | pgk3 | Phosphoglycerate kinase; High confidence in function and specificity; Belongs to the phosphoglycerate kinase family. (403 aa) |
| | pfkA | 6-phosphofructokinase; ATP-dependent phosphofructokinase, prokaryotic; High confidence in function and specificity. (323 aa) |
| | BN140_2190 | AMP-dependent synthetase/ligase, Domain of unknown function (DUF3448); High confidence in function and specificity. (627 aa) |
| | BN140_2192 | Phosphoadenosine phosphosulfate reductase family; High confidence in function and specificity. (469 aa) |
| | fdhB3 | Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal, N-term; High confidence in function and specificity. (412 aa) |
| | fdhA3 | Formate dehydrogenase, alpha subunit, Molybdopterin oxidoreductase; High confidence in function and specificity. (689 aa) |
| | fmdE | Formylmethanofuran dehydrogenase, subunit E domain, TFIIB zinc-binding; High confidence in function and specificity. (213 aa) |
| | BN140_2234 | Acylphosphatase-like; Specificity unclear. (113 aa) |
| | BN140_2246 | Fructose-bisphosphate aldolase, class I; DeoC/LacD family aldolase; High confidence in function and specificity. (306 aa) |
| | pfp | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (344 aa) |
| | cooS | Carbon-monoxide dehydrogenase, catalytic subunit, Prismane/CO dehydrogenase family; High confidence in function and specificity. (636 aa) |
| | BN140_2354 | Hypothetical protein; Formylmethanofuran dehydrogenase, subunit E domain, FmdE, Molybdenum formylmethanofuran dehydrogenase operon. (145 aa) |
| | frhD3 | Coenzyme F420 hydrogenase delta subunit; Peptidase A31, hydrogen uptake protein, Hydrogenase maturation protease; Specificity unclear. (158 aa) |
| | acsC | Acetyl-CoA decarbonylase/synthase complex, gamma subunit, CO dehydrogenase/acetyl-CoA synthase delta subunit; High confidence in function and specificity. (444 aa) |
| | acsD | CO dehydrogenase/acetyl-CoA synthase delta subunit; High confidence in function and specificity. (303 aa) |
| | acsB | Bifunctional acetyl-CoA decarbonylase/synthase complex subunit alpha/beta; In acetogenic organisms, this enzyme complex converts carbon dioxide to acetyl-CoA while in methanogenic organisms this enzyme is used to degrade acetyl-CoA to form methane and carbon dioxide; part of an enzyme complex; High confidence in function and specificity. (673 aa) |
| | BN140_2383 | AMP-dependent synthetase/ligase; High confidence in function and specificity. (466 aa) |
| | BN140_2388 | AMP-dependent synthetase/ligase; High confidence in function and specificity. (462 aa) |
| | BN140_2389 | AMP-dependent synthetase/ligase; High confidence in function and specificity. (475 aa) |
| | glnA3 | Glutamine synthetase, catalytic domain; High confidence in function and specificity. (501 aa) |
| | pyk | Pyruvate kinase, alpha/beta domain; High confidence in function and specificity; Belongs to the pyruvate kinase family. (499 aa) |
| | BN140_2501 | acetyl-CoA C-acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; High confidence in function and specificity. (386 aa) |
| | fwdE | Formylmethanofuran dehydrogenase, subunit E domain, FmdE, Molybdenum formylmethanofuran dehydrogenase operon; High confidence in function and specificity. (214 aa) |
| | ldh | Lactate/malate dehydrogenase, C-terminal; High confidence in function and specificity. (419 aa) |
| | BN140_2598 | ROK, Glucokinase; High confidence in function and specificity. (322 aa) |
| | gap | Glyceraldehyde-3-phosphate dehydrogenase, type II, C-terminal domain; High confidence in function and specificity. (341 aa) |
| | BN140_3013 | Coenzyme F420-0 gamma-glutamyl ligase. (268 aa) |
| | leuB3 | 3-isopropylmalate dehydrogenase. (322 aa) |
