STRINGSTRING
glyA glyA ilvD ilvD aroB aroB hisE hisE metE metE glyQ glyQ dapF dapF lysA lysA argH argH ilvE ilvE dapD dapD ileS ileS ilvI ilvI ilvC ilvC thrA thrA thrC thrC trpS trpS valS valS lysC lysC metF metF dapA dapA argG argG metG metG gltX gltX leuS leuS aroH aroH pheS pheS hisI hisI serS serS aroD aroD asd asd leuB leuB leuD leuD leuC leuC aroC aroC leuA leuA putA putA aspS aspS aroA aroA hisC hisC pdt pdt hisD hisD hisG hisG gnd gnd sufS sufS A33U_032 A33U_032 glnS glnS tyrS tyrS dapB dapB hisB hisB hisH hisH hisA hisA hisF hisF
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
glyASerine hydroxymethyltransferase. (401 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (549 aa)
aroB3-dehydroquinate synthase. (337 aa)
hisEphosphoribosyl-ATP pyrophosphohydrolase. (105 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (705 aa)
glyQglycyl-tRNA synthetase alpha subunit. (247 aa)
dapFDiaminopimelate epimerase. (248 aa)
lysADiaminopimelate decarboxylase. (398 aa)
argHPutative argininosuccinate lyase. (440 aa)
ilvEBranched-chain amino acid aminotransferase. (299 aa)
dapDTetrahydrodipicolinate N-succinyltransferase. (319 aa)
ileSisoleucyl-tRNA synthetase. (807 aa)
ilvIAcetolactate synthase large subunit; Belongs to the TPP enzyme family. (557 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (330 aa)
thrAHomoserine dehydrogenase. (377 aa)
thrCThreonine synthase. (439 aa)
trpStryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (292 aa)
valSPutative valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (632 aa)
lysCAspartokinase; Belongs to the aspartokinase family. (415 aa)
metFPutative 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (236 aa)
dapADihydrodipicolinate synthase; Belongs to the DapA family. (260 aa)
argGArgininosuccinate synthase. (351 aa)
metGmethionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (434 aa)
gltXPutative glutamyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (321 aa)
leuSleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (620 aa)
aroH3-deoxy-7-phosphoheptulonate synthase. (306 aa)
pheSPutative phenylalanyl-tRNA synthetase alpha subunit. (90 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family. (108 aa)
serSseryl-tRNA synthetase. (338 aa)
aroD3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (149 aa)
asdAspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (340 aa)
leuB3-isopropylmalate dehydrogenase. (349 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (185 aa)
leuC3-isopropylmalate dehydratase large subunit. (461 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (344 aa)
leuA2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (449 aa)
putADelta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1016 aa)
aspSaspartyl-tRNA synthetase. (419 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (407 aa)
hisCHistidinol phosphate aminotransferase. (320 aa)
pdtPutative prephenate dehydratase. (250 aa)
hisDHistidinol dehydrogenase. (410 aa)
hisGATP phosphoribosyltransferase. (173 aa)
gnd6-phosphogluconate dehydrogenase. (417 aa)
sufSPutative selenocysteine lyase. (385 aa)
A33U_032Hypothetical protein. (183 aa)
glnSglutaminyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (389 aa)
tyrStyrosyl-tRNA synthetase. (314 aa)
dapBDihydrodipicolinate reductase; Belongs to the DapB family. (231 aa)
hisBImidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (180 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit. (200 aa)
hisAPhosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; Belongs to the HisA/HisF family. (224 aa)
hisFImidazoleglycerol-phosphate synthase; Belongs to the HisA/HisF family. (243 aa)
Your Current Organism:
Carsonella ruddii CE Thao2000
NCBI taxonomy Id: 1202536
Other names: C. Carsonella ruddii CE isolate Thao2000, Candidatus Carsonella ruddii CE isolate Thao2000, endosymbiont of Ctenarytaina eucalypti isolate Thao2000
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