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| | coaBC | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (400 aa) |
| | rpoZ | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (57 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (181 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (250 aa) |
| | pyrD | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (311 aa) |
| | B005_0060 | Oxidoreductase NAD-binding domain protein. (293 aa) |
| | carB | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1102 aa) |
| | carA | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (380 aa) |
| | pyrC | Dihydroorotase, multifunctional complex type domain protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (433 aa) |
| | pyrB | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (302 aa) |
| | B005_0103 | Exonuclease, DNA polymerase III, epsilon subunit family domain protein. (570 aa) |
| | B005_0199 | Transketolase, thiamine diphosphate binding domain protein. (327 aa) |
| | B005_0209 | acetoacetate-CoA ligase. (663 aa) |
| | B005_0213 | Hypothetical protein. (449 aa) |
| | manA | Mannose-6-phosphate isomerase, class I. (425 aa) |
| | B005_0347 | Hypothetical protein. (199 aa) |
| | B005_0368 | Carbamoyl-phosphate synthase L chain, ATP binding domain protein. (367 aa) |
| | B005_0372 | RNA polymerase sigma factor, sigma-70 family protein; Belongs to the sigma-70 factor family. ECF subfamily. (161 aa) |
| | sigA | RNA polymerase principal sigma factor hrdB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (491 aa) |
| | nadD | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (189 aa) |
| | B005_0458 | Hypothetical protein. (725 aa) |
| | B005_0468 | AMP-binding enzyme family protein; Overlaps another CDS with the same product name. (102 aa) |
| | B005_0469 | AMP-binding enzyme family protein; Overlaps another CDS with the same product name. (436 aa) |
| | B005_0471 | paaX-like C-terminal domain protein. (177 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (134 aa) |
| | B005_0508 | Cytidyltransferase-like domain protein. (167 aa) |
| | B005_0569 | Thymidylate kinase family protein. (218 aa) |
| | ribF | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. (320 aa) |
| | nusA | Transcription elongation protein nusA; Participates in both transcription termination and antitermination. (344 aa) |
| | B005_0795 | Phosphotransferase enzyme family protein. (285 aa) |
| | B005_0859 | RNA polymerase sigma-70 factor, sigma-B/F/G subfamily protein. (252 aa) |
| | B005_0868 | RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (224 aa) |
| | B005_0886 | Hypothetical protein. (224 aa) |
| | B005_0954 | AMP-binding enzyme family protein. (265 aa) |
| | B005_0960 | Hypothetical protein. (148 aa) |
| | B005_1048 | Nucleotide sugar dehydrogenase family protein. (443 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (177 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (364 aa) |
| | B005_1066 | RNA polymerase sigma factor, sigma-70 family protein; Zinc-finger family protein; Belongs to the sigma-70 factor family. ECF subfamily. (199 aa) |
| | B005_1104 | Adenylate and Guanylate cyclase catalytic domain protein. (331 aa) |
| | add | Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (350 aa) |
| | folD | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (521 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (207 aa) |
| | prs | Ribose-phosphate diphosphokinase family protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (322 aa) |
| | glmU | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (468 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (526 aa) |
| | B005_1193 | Nitronate monooxygenase family protein. (362 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (496 aa) |
| | B005_1195 | RNA polymerase sigma factor, sigma-70 family protein; Belongs to the sigma-70 factor family. ECF subfamily. (169 aa) |
| | coaA | Pantothenate kinase. (314 aa) |
| | B005_1358 | R2-like ligand binding oxidase. (325 aa) |
| | B005_1381 | Hypothetical protein. (192 aa) |
| | B005_1413 | HD domain protein. (194 aa) |
| | strM | dTDP-4-dehydrorhamnose 3,5-epimerase. (181 aa) |
| | B005_1502 | carD-like/TRCF domain protein. (160 aa) |
| | B005_1512 | Putative membrane protein. (762 aa) |
| | B005_1525 | Hypothetical protein; May play a role in the intracellular transport of hydrophobic ligands. (187 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (489 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase. (354 aa) |
| | B005_1632 | RNA polymerase sigma factor, sigma-70 family protein. (411 aa) |
| | B005_1703 | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit. (371 aa) |
| | B005_1716 | RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (170 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (80 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (231 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (764 aa) |
| | B005_1748 | wbqC-like family protein. (272 aa) |
| | B005_1813 | Putative metal-dependent phosphohydrolase. (207 aa) |
| | B005_1828 | AMP-binding enzyme family protein. (418 aa) |
| | B005_1829 | Hypothetical protein. (225 aa) |
| | B005_1882 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (380 aa) |
| | serS | serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (427 aa) |
| | B005_1943 | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit. (361 aa) |
| | B005_1965 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (379 aa) |
| | B005_1982 | RNA polymerase sigma factor, sigma-70 family protein; Belongs to the sigma-70 factor family. ECF subfamily. (208 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (450 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (217 aa) |
| | dnaX | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (720 aa) |
| | pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (367 aa) |
| | B005_2151 | RNA polymerase sigma factor, sigma-70 family protein; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa) |
| | sigE | RNA polymerase sigma-E factor; Belongs to the sigma-70 factor family. ECF subfamily. (172 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (431 aa) |
| | purC | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family. (317 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (416 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (427 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (177 aa) |
| | B005_2254 | RNA polymerase sigma factor, sigma-70 family protein; Belongs to the sigma-70 factor family. ECF subfamily. (968 aa) |
| | B005_2259 | Ribonucleotide reductase, small chain family protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (358 aa) |
| | nadE | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (276 aa) |
| | B005_2275 | Hypothetical protein. (500 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (196 aa) |
| | B005_2519 | Carbamoyl-phosphate synthase L chain, ATP binding domain protein. (417 aa) |
| | B005_2527 | ATP-grasp domain protein. (417 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (702 aa) |
| | B005_2550 | Hypothetical protein. (177 aa) |
| | hpt | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (184 aa) |
| | coaX | Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (260 aa) |
| | B005_2646 | RNA polymerase sigma factor, sigma-70 family protein. (302 aa) |
| | nusG | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. (266 aa) |
| | rpoB | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1122 aa) |
| | rpoC | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1292 aa) |
| | adk | Adenylate kinase family protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (219 aa) |
| | rpoA | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (340 aa) |
| | hydA | Dihydropyrimidinase. (468 aa) |
| | B005_2899 | RNA polymerase sigma factor, sigma-70 family protein; Belongs to the sigma-70 factor family. ECF subfamily. (204 aa) |
| | B005_2955 | Thymidine kinase family protein. (183 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (157 aa) |
| | pyrH | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (248 aa) |
| | ligD | DNA polymerase LigD, polymerase domain protein. (304 aa) |
| | B005_3156 | Nitronate monooxygenase family protein. (479 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (660 aa) |
| | atpB | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (276 aa) |
| | atpE | ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (73 aa) |
| | atpF | ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (181 aa) |
| | atpH | ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (273 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (546 aa) |
| | atpG | ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (282 aa) |
| | atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (481 aa) |
| | atpC | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (129 aa) |
| | B005_3225 | Putative aTP/GTP-binding protein. (81 aa) |
| | B005_3239 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. (193 aa) |
| | B005_3247 | Isochorismatase family protein. (190 aa) |
| | B005_3248 | Nicotinate phosphoribosyltransferase family protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (433 aa) |
| | B005_3265 | rNA polymerase, sigma-24 subunit, ECF subfamily. (465 aa) |
| | nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (332 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (295 aa) |
| | B005_3305 | AMP-binding enzyme family protein. (571 aa) |
| | B005_3486 | DNA polymerase A family protein. (593 aa) |
| | B005_3549 | Competence/damage-inducible CinA C-terminal domain protein; Belongs to the CinA family. (186 aa) |
| | B005_3610 | RNA polymerase sigma-70 factor, sigma-E family protein; Belongs to the sigma-70 factor family. ECF subfamily. (176 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (941 aa) |
| | B005_3654 | RNA polymerase principal sigma factor hrdB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (344 aa) |
| | kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (412 aa) |
| | pyrD-2 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (379 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (184 aa) |
| | relA | Bifunctional (p)ppGpp synthase/hydrolase relA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (725 aa) |
| | priA | Putative primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (681 aa) |
| | nusB | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (137 aa) |
| | dinB | impB/mucB/samB family protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (428 aa) |
| | B005_3820 | Acetyltransferase family protein. (145 aa) |
| | dnaE | DNA polymerase III, alpha subunit. (1186 aa) |
| | polA | DNA polymerase I family protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (920 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (546 aa) |
| | cmk | Cytidylate kinase. (229 aa) |
| | B005_3955 | RNA polymerase sigma factor, sigma-70 family protein; Belongs to the sigma-70 factor family. ECF subfamily. (333 aa) |
| | B005_4053 | Sigma-70, region 4 family protein. (657 aa) |
| | thyX | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (265 aa) |
| | B005_4300 | AMP-binding enzyme family protein. (455 aa) |
| | B005_4327 | Queuosine biosynthesis family protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (354 aa) |
| | B005_4421 | Flavofamily protein. (170 aa) |
| | B005_4452 | Acetyltransferase family protein. (365 aa) |
| | B005_4510 | Hypothetical protein. (132 aa) |
| | B005_4518 | Putative RNA polymerase sigma-C factor; Belongs to the sigma-70 factor family. ECF subfamily. (190 aa) |
| | B005_4568 | Phosphoribulokinase / Uridine kinase family protein. (238 aa) |
| | B005_4639 | AMP-binding enzyme family protein. (558 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (359 aa) |
| | B005_4756 | Putative aminoglycoside-2''-adenylyltransferase. (215 aa) |
| | B005_4808 | RNA polymerase, sigma-24 subunit, ECF subfamily domain protein. (124 aa) |
| | B005_4809 | Sigma-70 region 2 family protein; Belongs to the sigma-70 factor family. (208 aa) |
| | B005_4953 | RNA polymerase sigma factor, sigma-70 family protein. (275 aa) |
| | B005_5080 | Acetyltransferase family protein. (213 aa) |
| | purB | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (476 aa) |
| | B005_5136 | ATP-grasp domain protein. (453 aa) |
| | B005_5140 | RNA polymerase sigma factor, sigma-70 family protein. (285 aa) |
| | B005_5151 | RNA polymerase sigma factor, sigma-70 family protein. (273 aa) |
| | B005_5236 | RNA polymerase sigma factor, sigma-70 family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (470 aa) |
| | B005_5294 | Hypothetical protein. (430 aa) |
| | B005_5390 | Phosphoribulokinase / Uridine kinase family protein. (180 aa) |
| | B005_5400 | RNA polymerase sigma factor, sigma-70 family protein; Belongs to the sigma-70 factor family. ECF subfamily. (196 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (148 aa) |
| | ppnK | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (290 aa) |
