(10 nodes) Fatty acid biosynthesis network (Kinetoplastibacterium desouzaii)

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	CDSE_0021	Enoyl-[acyl-carrier protein] reductase I; Acyl-carrier-protein; SecretomeP prediction: 0.08; Protein involved in oxidation-reduction process. (258 aa)
	CDSE_0044	acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
	CDSE_0045	acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (142 aa)
	accA	acetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa)
	fabZ	3R-hydroxymyristoyl ACP dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (150 aa)
	CDSE_0739	3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (409 aa)
	CDSE_0741	3-oxoacyl-[acyl-carrier protein] reductase; Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only; SecretomeP prediction: 0.06; Protein involved in oxidation-reduction process. (245 aa)
	CDSE_0742	[acyl-carrier-protein] S-malonyltransferase; Lipid metabolism; SecretomeP prediction: 0.1; Protein involved in transferase activity and fatty acid biosynthetic process. (310 aa)
	fabH	3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (327 aa)
	accD	acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (286 aa)

Your Current Organism:

Kinetoplastibacterium desouzaii

NCBI taxonomy Id: 1208919
Other names: C. Kinetoplastibacterium desouzaii TCC079E, Candidatus Kinetoplastibacterium desouzaii TCC079E

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDSE_0021	CDSE_0739	CDSE_0021	CDSE_0739	Enoyl-[acyl-carrier protein] reductase I; Acyl-carrier-protein; SecretomeP prediction: 0.08; Protein involved in oxidation-reduction process.	3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.	0.980
CDSE_0021	CDSE_0741	CDSE_0021	CDSE_0741	Enoyl-[acyl-carrier protein] reductase I; Acyl-carrier-protein; SecretomeP prediction: 0.08; Protein involved in oxidation-reduction process.	3-oxoacyl-[acyl-carrier protein] reductase; Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only; SecretomeP prediction: 0.06; Protein involved in oxidation-reduction process.	0.941
CDSE_0021	CDSE_0742	CDSE_0021	CDSE_0742	Enoyl-[acyl-carrier protein] reductase I; Acyl-carrier-protein; SecretomeP prediction: 0.08; Protein involved in oxidation-reduction process.	[acyl-carrier-protein] S-malonyltransferase; Lipid metabolism; SecretomeP prediction: 0.1; Protein involved in transferase activity and fatty acid biosynthetic process.	0.979
CDSE_0021	accA	CDSE_0021	CDSE_0395	Enoyl-[acyl-carrier protein] reductase I; Acyl-carrier-protein; SecretomeP prediction: 0.08; Protein involved in oxidation-reduction process.	acetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	0.631
CDSE_0021	accD	CDSE_0021	CDSE_0752	Enoyl-[acyl-carrier protein] reductase I; Acyl-carrier-protein; SecretomeP prediction: 0.08; Protein involved in oxidation-reduction process.	acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.	0.526
CDSE_0021	fabH	CDSE_0021	CDSE_0743	Enoyl-[acyl-carrier protein] reductase I; Acyl-carrier-protein; SecretomeP prediction: 0.08; Protein involved in oxidation-reduction process.	3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.	0.529
CDSE_0021	fabZ	CDSE_0021	CDSE_0580	Enoyl-[acyl-carrier protein] reductase I; Acyl-carrier-protein; SecretomeP prediction: 0.08; Protein involved in oxidation-reduction process.	3R-hydroxymyristoyl ACP dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.	0.936
CDSE_0044	CDSE_0045	CDSE_0044	CDSE_0045	acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.999
CDSE_0044	CDSE_0739	CDSE_0044	CDSE_0739	acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.	0.532
CDSE_0044	CDSE_0742	CDSE_0044	CDSE_0742	acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	[acyl-carrier-protein] S-malonyltransferase; Lipid metabolism; SecretomeP prediction: 0.1; Protein involved in transferase activity and fatty acid biosynthetic process.	0.932
CDSE_0044	accA	CDSE_0044	CDSE_0395	acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	acetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	0.955
CDSE_0044	accD	CDSE_0044	CDSE_0752	acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.	0.991
CDSE_0044	fabH	CDSE_0044	CDSE_0743	acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.	0.927
CDSE_0045	CDSE_0044	CDSE_0045	CDSE_0044	acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.999
CDSE_0045	CDSE_0742	CDSE_0045	CDSE_0742	acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	[acyl-carrier-protein] S-malonyltransferase; Lipid metabolism; SecretomeP prediction: 0.1; Protein involved in transferase activity and fatty acid biosynthetic process.	0.943
CDSE_0045	accA	CDSE_0045	CDSE_0395	acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	acetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	0.989
CDSE_0045	accD	CDSE_0045	CDSE_0752	acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.	0.995
CDSE_0045	fabH	CDSE_0045	CDSE_0743	acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.	0.966
CDSE_0045	fabZ	CDSE_0045	CDSE_0580	acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	3R-hydroxymyristoyl ACP dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.	0.658
CDSE_0739	CDSE_0021	CDSE_0739	CDSE_0021	3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.	Enoyl-[acyl-carrier protein] reductase I; Acyl-carrier-protein; SecretomeP prediction: 0.08; Protein involved in oxidation-reduction process.	0.980