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gloB gloB CDSE_0044 CDSE_0044 CDSE_0045 CDSE_0045 CDSE_0098 CDSE_0098 leuA leuA ppc ppc accA accA CDSE_0547 CDSE_0547 CDSE_0548 CDSE_0548 CDSE_0549 CDSE_0549 CDSE_0585 CDSE_0585 CDSE_0710 CDSE_0710 CDSE_0715 CDSE_0715 CDSE_0722 CDSE_0722 accD accD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (281 aa)
CDSE_0044acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
CDSE_0045acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (142 aa)
CDSE_0098L-lactate dehydrogenase; Energy production and conversion; SecretomeP prediction: 0.59; Protein involved in oxidation-reduction process; Belongs to the LDH2/MDH2 oxidoreductase family. (349 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (558 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (941 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa)
CDSE_0547Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (903 aa)
CDSE_0548Pyruvate dehydrogenase E2 component; Energy production and conversion; SecretomeP prediction: 0.21; Protein involved in lipoic acid binding. (449 aa)
CDSE_0549Dihydrolipoamide dehydrogenase; Energy production and conversion; SecretomeP prediction: 0.05; Protein involved in oxidation-reduction process. (567 aa)
CDSE_0585Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (787 aa)
CDSE_0710Dihydrolipoamide dehydrogenase; Energy production and conversion; SecretomeP prediction: 0.38; Protein involved in oxidation-reduction process. (474 aa)
CDSE_0715Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Energy production and conversion; SecretomeP prediction: 0.11; Protein involved in oxidation-reduction process. (761 aa)
CDSE_0722acetyl-CoA synthetase; Lipid metabolism; SecretomeP prediction: 0.09; Protein involved in ligase activity. (660 aa)
accDacetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (286 aa)
Your Current Organism:
Kinetoplastibacterium desouzaii
NCBI taxonomy Id: 1208919
Other names: C. Kinetoplastibacterium desouzaii TCC079E, Candidatus Kinetoplastibacterium desouzaii TCC079E
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