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cobB cobB AEE90649.1 AEE90649.1 cbiC cbiC cbiD cbiD AEE90652.1 AEE90652.1 cbiT cbiT AEE90654.1 AEE90654.1 cbiF cbiF AEE90656.1 AEE90656.1 cbiH cbiH AEE90658.1 AEE90658.1 hemA hemA hemC hemC AEE90661.1 AEE90661.1 hemB hemB AEE90663.1 AEE90663.1 hemL hemL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
cobBCobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (457 aa)
AEE90649.1PFAM: Cobalamin (vitamin B12) biosynthesis CbiX; KEGG: thx:Thet_0350 cobalamin (vitamin B12) biosynthesis CbiX protein. (124 aa)
cbiCKEGG: tmt:Tmath_0421 precorrin-8X methylmutase; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core. (217 aa)
cbiDcobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (357 aa)
AEE90652.1KEGG: toc:Toce_0312 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; PFAM: Tetrapyrrole methylase. (213 aa)
cbiTKEGG: toc:Toce_0313 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core; PFAM: Protein of unknown function Met10. (204 aa)
AEE90654.1Precorrin-2 C20-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobI/CbiL, precorrin-2 C20-methyltransferase, core; KEGG: ttm:Tthe_1842 precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole methylase. (227 aa)
cbiFPrecorrin-4 C11-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; KEGG: toc:Toce_0315 precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole methylase. (246 aa)
AEE90656.1KEGG: toc:Toce_0316 cobalamin (vitamin B12) biosynthesis CbiG protein; manually curated; PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core. (368 aa)
cbiHprecorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; KEGG: tit:Thit_0358 precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole methylase. (243 aa)
AEE90658.1KEGG: tit:Thit_0359 precorrin-6x reductase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase; PFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase. (251 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (436 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (293 aa)
AEE90661.1TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; KEGG: tmt:Tmath_0432 uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase. (509 aa)
hemBKEGG: ttm:Tthe_1595 porphobilinogen synthase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; Belongs to the ALAD family. (326 aa)
AEE90663.1TIGRFAM: Sirohaem synthase, N-terminal; KEGG: tpd:Teth39_1888 glutamate-1-semialdehyde-2,1-aminomutase. (189 aa)
hemLGlutamate-1-semialdehyde 2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; HAMAP: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; KEGG: thx:Thet_0364 glutamate-1-semialdehyde-2,1-aminomutase. (425 aa)
Your Current Organism:
Tepidanaerobacter acetatoxydans
NCBI taxonomy Id: 1209989
Other names: T. acetatoxydans Re1, Tepidanaerobacter acetatoxydans Re1, Tepidanaerobacter acetatoxydans str. Re1, Tepidanaerobacter acetatoxydans strain Re1, Tepidanaerobacter sp. Re1
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