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| | AEE91900.1 | PFAM: Glycosyl transferase, group 1; KEGG: has:Halsa_0575 glycosyl transferase group 1. (375 aa) |
| | AEE91895.1 | PFAM: Glycosyl transferase, group 1; KEGG: elm:ELI_2403 glycosyl transferase group 1. (374 aa) |
| | murJ | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (506 aa) |
| | AEE91828.1 | KEGG: bbe:BBR47_31640 SelA-related pyridoxal phosphate-dependent enzyme; TIGRFAM: Pyridoxal phosphate-dependent enzyme, SelA-like; PFAM: Pyridoxal phosphate-dependent transferase. (367 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (491 aa) |
| | AEE91820.1 | PFAM: YkuD domain; KEGG: cno:NT01CX_0764 ErfK/YbiS/YcfS/YnhG family protein. (266 aa) |
| | AEE91813.1 | PFAM: Glycosyl transferase, group 1; KEGG: sth:STH1098 group 1 family glycosyl transferase. (381 aa) |
| | AEE91811.1 | PFAM: O-antigen ligase-related; KEGG: sth:STH1100 hypothetical protein. (635 aa) |
| | AEE91810.1 | PFAM: Glycosyl transferase, group 1; KEGG: tjr:TherJR_2108 glycosyl transferase group 1. (364 aa) |
| | tarA | Glycosyl transferase, WecB/TagA/CpsF family; Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid. (253 aa) |
| | AEE91790.1 | PFAM: Asp/Glu/hydantoin racemase; KEGG: toc:Toce_2193 Asp/Glu/hydantoin racemase; Belongs to the aspartate/glutamate racemases family. (223 aa) |
| | mrdB | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (365 aa) |
| | rplU | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (103 aa) |
| | rpmA | TIGRFAM: Ribosomal protein L27; HAMAP: Ribosomal protein L27; KEGG: toc:Toce_0765 LSU ribosomal protein L27P; PFAM: Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (90 aa) |
| | leuS | TIGRFAM: Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial; KEGG: toc:Toce_0772 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (816 aa) |
| | uppP | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (268 aa) |
| | valS | Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (883 aa) |
| | AEE91621.1 | PFAM: Fibronectin-binding A, N-terminal; Domain of unknown function DUF814; KEGG: toc:Toce_1017 fibronectin-binding A domain protein. (588 aa) |
| | def | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (154 aa) |
| | fmt | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (312 aa) |
| | AEE91605.1 | TIGRFAM: Ribosomal protein L28; HAMAP: Ribosomal protein L28; KEGG: toc:Toce_1035 LSU ribosomal protein L28P; PFAM: Ribosomal protein L28. (62 aa) |
| | AEE91591.1 | TIGRFAM: Ribosomal protein L32p; HAMAP: Ribosomal protein L32p; KEGG: toc:Toce_1050 LSU ribosomal protein L32P; PFAM: Ribosomal protein L32p. (62 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (590 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (876 aa) |
| | mltG | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (361 aa) |
| | efp | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (185 aa) |
| | AEE91526.1 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; KEGG: toc:Toce_1270 serine-type D-Ala-D-Ala carboxypeptidase; SMART: Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal. (388 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (327 aa) |
| | AEE91504.1 | KEGG: hmo:HM1_2742 hypothetical protein. (488 aa) |
| | rpsO | Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (665 aa) |
| | proS | Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (478 aa) |
| | frr | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa) |
| | tsf | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (205 aa) |
| | rpsB | Ribosomal protein S2; KEGG: toc:Toce_1257 SSU ribosomal protein S2P; TIGRFAM: Ribosomal protein S2, bacteria/mitochondria/plastid; PFAM: Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (233 aa) |
| | rplS | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (113 aa) |
| | ylqC | HAMAP: Uncharacterised protein family UPF0109, bacterial; KEGG: toc:Toce_1067 RNA-binding protein (KH domain); Belongs to the UPF0109 family. (75 aa) |
| | rpsP | TIGRFAM: Ribosomal protein S16; HAMAP: Ribosomal protein S16; KEGG: toc:Toce_1066 SSU ribosomal protein S16P; PFAM: Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (97 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (418 aa) |
| | murC | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (468 aa) |
| | murG | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (374 aa) |
| | spoVE | Stage V sporulation protein E; KEGG: toc:Toce_0951 spore cortex peptidoglycan biosynthesis regulator SpoVE; TIGRFAM: Stage V sporulation protein E; Cell division protein FtsW; PFAM: Cell cycle protein; Belongs to the SEDS family. (365 aa) |
| | murD | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (468 aa) |
| | mraY | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (319 aa) |
| | murE | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (482 aa) |
| | rpsU | TIGRFAM: Ribosomal protein S21; HAMAP: Ribosomal protein S21; KEGG: cac:CA_C1288 30S ribosomal protein S21; PFAM: Ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (60 aa) |
| | lepA | GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (601 aa) |
| | rpsT | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (90 aa) |
| | AEE91217.1 | KEGG: tpd:Teth39_1543 phosphoesterase, PA-phosphatase related; PFAM: Phosphatidic acid phosphatase type 2/haloperoxidase; SMART: Phosphatidic acid phosphatase type 2/haloperoxidase. (281 aa) |
| | smpB | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (155 aa) |
| | AEE91157.1 | PFAM: Acyltransferase 3; KEGG: tjr:TherJR_2911 hypothetical protein. (371 aa) |
| | AEE91118.1 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; KEGG: toc:Toce_0780 serine-type D-Ala-D-Ala carboxypeptidase; SMART: Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal. (415 aa) |
| | prfB | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (365 aa) |
| | AEE90975.1 | PFAM: Glycosyl transferase, family 2; KEGG: mta:Moth_1660 glycosyl transferase family protein. (249 aa) |
| | AEE90917.1 | PFAM: CobB/CobQ-like glutamine amidotransferase; KEGG: tte:TTE0007 glutamine amidotransferase. (240 aa) |
| | AEE90916.1 | PFAM: Domain of unknown function DUF1727; Mur ligase, central; KEGG: dau:Daud_0588 hypothetical protein. (460 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (303 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1045 aa) |
| | AEE90870.1 | KEGG: toc:Toce_1390 penicillin-binding protein, 1A family; TIGRFAM: Penicillin-binding protein 1A; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase. (800 aa) |
| | pheT | KEGG: toc:Toce_1396 phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; HAMAP: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial. (798 aa) |
| | pheS | TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; HAMAP: Phenylalanyl-tRNA synthetase alpha chain 1, bacterial; KEGG: toc:Toce_1397 phenylalanyl-tRNA synthetase, alpha subunit; PFAM: Phenylalanyl-tRNA synthetase; Phenylalanyl-tRNA synthetase, class II, N-terminal. (338 aa) |
| | rplT | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa) |
| | AEE90858.1 | TIGRFAM: Ribosomal protein L35, non-mitochondrial; HAMAP: Ribosomal protein L35, non-mitochondrial; KEGG: toc:Toce_1403 LSU ribosomal protein L35P; PFAM: Ribosomal protein L35. (65 aa) |
| | infC | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (189 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (636 aa) |
| | glyQS | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (460 aa) |
| | AEE90721.1 | KEGG: chy:CHY_2654 hypothetical protein. (1188 aa) |
| | lgt | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (255 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (363 aa) |
| | serS | Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (425 aa) |
| | lysS | PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; TIGRFAM: Lysyl-tRNA synthetase, class II; HAMAP: Lysyl-tRNA synthetase, class II; KEGG: toc:Toce_0164 lysyl-tRNA synthetase. (493 aa) |
| | rpsI | PFAM: Ribosomal protein S9; KEGG: toc:Toce_0154 SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (129 aa) |
| | rplM | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (144 aa) |
| | rplQ | TIGRFAM: Ribosomal protein L17; HAMAP: Ribosomal protein L17; KEGG: toc:Toce_0148 LSU ribosomal protein L17P; PFAM: Ribosomal protein L17. (110 aa) |
| | rpsD | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (208 aa) |
| | AEE90424.1 | KEGG: toc:Toce_0145 SSU ribosomal protein S11P; TIGRFAM: Ribosomal protein S11, bacterial-type; PFAM: Ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family. (127 aa) |
| | AEE90423.1 | KEGG: toc:Toce_0144 SSU ribosomal protein S13P; TIGRFAM: Ribosomal protein S13, bacterial-type; PFAM: Ribosomal protein S13; Belongs to the universal ribosomal protein uS13 family. (122 aa) |
| | AEE90422.1 | TIGRFAM: Ribosomal protein L36; HAMAP: Ribosomal protein L36; KEGG: cce:Ccel_0783 50S ribosomal protein L36; PFAM: Ribosomal protein L36. (37 aa) |
| | infA | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa) |
| | AEE90420.1 | KEGG: toc:Toce_0141 LSU ribosomal protein L14E. (99 aa) |
| | rplO | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (146 aa) |
| | rpsE | Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (168 aa) |
| | rplR | Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (121 aa) |
| | rplF | Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (179 aa) |
| | rpsH | Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa) |
| | rpsNA | Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa) |
| | rplE | Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (178 aa) |
| | rplX | Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (107 aa) |
| | rplNA | Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa) |
| | rpsQ | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (86 aa) |
| | rpmC | KEGG: toc:Toce_0127 LSU ribosomal protein L29P; TIGRFAM: Ribosomal protein L29; PFAM: Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (71 aa) |
| | rplP | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (144 aa) |
| | rpsC | Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (231 aa) |
| | rplV | Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (112 aa) |
| | rpsS | Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (94 aa) |
| | rplB | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (275 aa) |
| | rplW | Ribosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (96 aa) |
| | rplD | Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel. (208 aa) |
| | rplC | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (211 aa) |
| | AEE90397.1 | TIGRFAM: Ribosomal protein S10 subgroup; HAMAP: Ribosomal protein S10 subgroup; KEGG: toc:Toce_0118 SSU ribosomal protein S10P; PFAM: Ribosomal protein S10. (102 aa) |
| | tufA | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (401 aa) |
| | fusA | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (688 aa) |
| | rpsG | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) |
| | rpsL | Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (126 aa) |
| | AEE90392.1 | PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45; KEGG: toc:Toce_0113 LSU ribosomal protein L7AE. (82 aa) |
| | yabR | KEGG: toc:Toce_0109 RNA binding S1 domain protein; PFAM: Ribosomal protein S1, RNA-binding domain; SMART: RNA-binding domain, S1. (131 aa) |
| | AEE90330.1 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (336 aa) |
| | pth | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (189 aa) |
| | rplY | 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (210 aa) |
| | glmU | Bifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (465 aa) |
| | metG | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (650 aa) |
| | rpmH | PFAM: Ribosomal protein L34; manually curated; TIGRFAM: Ribosomal protein L34; KEGG: toc:Toce_2285 LSU ribosomal protein L34P; HAMAP: Ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (44 aa) |
| | rpsF | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (95 aa) |
| | rpsR | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (74 aa) |
| | rplI | 50S ribosomal protein L9; Binds to the 23S rRNA. (148 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (269 aa) |
| | argS | KEGG: toc:Toce_2184 arginyl-tRNA synthetase; TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic. (569 aa) |
| | AEE92556.1 | PFAM: Methicillin resistance protein; KEGG: mta:Moth_2408 methicillin resistance protein. (360 aa) |
| | AEE92533.1 | Addiction module toxin, RelE/StbE family; KEGG: clo:HMPREF0868_1572 RelE family toxin-antitoxin system toxin protein; TIGRFAM: Addiction module toxin, RelE/StbE; PFAM: Plasmid stabilisation system. (91 aa) |
| | AEE92507.1 | KEGG: gyc:GYMC61_0643 phage related protein. (365 aa) |
| | AEE92478.1 | KEGG: nth:Nther_1011 hypothetical protein. (432 aa) |
| | fusA-2 | TIGRFAM: Translation elongation factor EFG/EF2; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; KEGG: toc:Toce_2128 translation elongation factor 2 (EF-2/EF-G); SMART: Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal. (690 aa) |
| | cysS | SMART: Cysteinyl-tRNA synthetase, class Ia, DALR; TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; KEGG: toc:Toce_2114 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase, class Ia; Cysteinyl-tRNA synthetase, class Ia, DALR; Belongs to the class-I aminoacyl-tRNA synthetase family. (466 aa) |
| | AEE92288.1 | KEGG: toc:Toce_2107 translation elongation factor 1A (EF-1A/EF-Tu); TIGRFAM: Translation elongation factor EFTu/EF1A, bacterial/organelle; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFTu/EF1A, C-terminal. (401 aa) |
| | rpmGA | PFAM: Ribosomal protein L33; manually curated; TIGRFAM: Ribosomal protein L33; KEGG: toc:Toce_2106 LSU ribosomal protein L33P; HAMAP: Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (49 aa) |
| | rplK | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (140 aa) |
| | rplA | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (233 aa) |
| | rplJ | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (172 aa) |
| | rplL | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (125 aa) |
| | rpmEA | 50S ribosomal protein L31; Binds the 23S rRNA. (69 aa) |
| | prfA | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (356 aa) |
| | rffE | TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: toc:Toce_2061 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase. (385 aa) |
| | murAA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (416 aa) |
| | tyrS | Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (409 aa) |
| | AEE92061.1 | KEGG: cdl:CDR20291_1056 putative glycosyltransferase. (276 aa) |
| | hisS | PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding; TIGRFAM: Histidyl-tRNA synthetase, class IIa, subgroup; HAMAP: Histidyl-tRNA synthetase, class IIa, subgroup; KEGG: ctc:CTC01958 histidyl-tRNA synthetase. (438 aa) |
| | gatC-2 | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (96 aa) |
| | gatA | Glutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (491 aa) |
| | gatB | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (472 aa) |
| | AEE91910.1 | PFAM: Lipopolysaccharide biosynthesis; KEGG: cth:Cthe_2347 lipopolysaccharide biosynthesis. (430 aa) |
| | AEE91909.1 | PFAM: O-antigen ligase-related; KEGG: toc:Toce_0487 O-antigen polymerase. (1003 aa) |
