STRINGSTRING
serC serC gcvPA gcvPA gcvPB gcvPB AEE90629.1 AEE90629.1 cysA cysA hemL hemL hisC hisC mdeA mdeA rocD rocD AEE91151.1 AEE91151.1 yugH yugH AEE91476.1 AEE91476.1 ltaA ltaA iscS iscS AEE91829.1 AEE91829.1 AEE91832.1 AEE91832.1 AEE91901.1 AEE91901.1 tpl tpl mdeA-2 mdeA-2 patB patB AEE92167.1 AEE92167.1 glyA glyA tnaA tnaA patB-2 patB-2 AEE92630.1 AEE92630.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (363 aa)
gcvPAGlycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (443 aa)
gcvPBGlycine dehydrogenase (decarboxylating) subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (482 aa)
AEE90629.1TIGRFAM: Cysteine desulfurase-related, unknown function; KEGG: csh:Closa_1018 cysteine desulfurase family protein; PFAM: Aminotransferase, class V/Cysteine desulfurase. (380 aa)
cysAKEGG: toc:Toce_1559 methionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme. (396 aa)
hemLGlutamate-1-semialdehyde 2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; HAMAP: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; KEGG: thx:Thet_0364 glutamate-1-semialdehyde-2,1-aminomutase. (425 aa)
hisCPFAM: Aminotransferase, class I/classII; TIGRFAM: Histidinol-phosphate aminotransferase; HAMAP: Histidinol-phosphate aminotransferase; KEGG: toc:Toce_1416 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (373 aa)
mdeATIGRFAM: Methionine gamma-lyase; KEGG: toc:Toce_1559 methionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme. (399 aa)
rocDAcetylornithine/succinyldiaminopimelate aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (396 aa)
AEE91151.1KEGG: toc:Toce_1422 L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase, class I/classII. (382 aa)
yugHAspartate transaminase; KEGG: thx:Thet_0277 class I/II aminotransferase; PFAM: Aminotransferase, class I/classII. (387 aa)
AEE91476.1Aspartate transaminase; KEGG: toc:Toce_1173 aminotransferase class I and II; PFAM: Aminotransferase, class I/classII. (400 aa)
ltaAKEGG: toc:Toce_0664 L-threonine aldolase; PFAM: Aromatic amino acid beta-eliminating lyase/threonine aldolase. (344 aa)
iscSCysteine desulfurase; KEGG: toc:Toce_1465 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase. (386 aa)
AEE91829.1Cystathionine beta-lyase; KEGG: kol:Kole_0146 aminotransferase class I and II; PFAM: Aminotransferase, class I/classII. (390 aa)
AEE91832.1Alanine--glyoxylate transaminase; KEGG: slp:Slip_0009 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase. (385 aa)
AEE91901.1PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: has:Halsa_0577 DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (386 aa)
tplTIGRFAM: Tyrosine phenol-lyase; KEGG: csh:Closa_0252 tyrosine phenol-lyase; PFAM: Aromatic amino acid beta-eliminating lyase/threonine aldolase. (459 aa)
mdeA-2PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; KEGG: tmt:Tmath_1425 Cys/Met metabolism pyridoxal-phosphate-dependent protein. (393 aa)
patBCystathionine beta-lyase; KEGG: kol:Kole_0146 aminotransferase class I and II; PFAM: Aminotransferase, class I/classII. (393 aa)
AEE92167.1Histidinol-phosphate transaminase; KEGG: tsi:TSIB_1557 hypothetical protein; PFAM: Aminotransferase, class I/classII. (377 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa)
tnaAHAMAP: Tryptophanase; KEGG: cno:NT01CX_2071 tryptophanase; PFAM: Aromatic amino acid beta-eliminating lyase/threonine aldolase. (460 aa)
patB-2Cystathionine beta-lyase; KEGG: aar:Acear_2286 aminotransferase class I and II; PFAM: Aminotransferase, class I/classII. (396 aa)
AEE92630.1PFAM: HTH transcriptional regulator, GntR; Aminotransferase, class I/classII; KEGG: toc:Toce_2207 transcriptional regulator, GntR family with aminotransferase domain; SMART: HTH transcriptional regulator, GntR. (497 aa)
Your Current Organism:
Tepidanaerobacter acetatoxydans
NCBI taxonomy Id: 1209989
Other names: T. acetatoxydans Re1, Tepidanaerobacter acetatoxydans Re1, Tepidanaerobacter acetatoxydans str. Re1, Tepidanaerobacter acetatoxydans strain Re1, Tepidanaerobacter sp. Re1
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