STRINGSTRING
B277_00595 B277_00595 B277_01094 B277_01094 B277_01099 B277_01099 B277_01124 B277_01124 B277_01129 B277_01129 B277_01134 B277_01134 B277_01139 B277_01139 fabG fabG B277_01149 B277_01149 B277_02239 B277_02239 B277_02491 B277_02491 B277_02496 B277_02496 B277_02501 B277_02501 B277_02631 B277_02631 B277_04040 B277_04040 B277_04045 B277_04045 B277_04227 B277_04227 B277_04232 B277_04232 B277_04757 B277_04757 B277_05264 B277_05264 B277_05578 B277_05578 B277_05953 B277_05953 B277_06433 B277_06433 B277_07391 B277_07391 B277_07396 B277_07396 B277_08974 B277_08974 B277_09177 B277_09177 B277_09217 B277_09217 B277_09222 B277_09222 B277_09287 B277_09287 B277_09292 B277_09292 B277_09682 B277_09682 B277_09747 B277_09747 B277_09752 B277_09752 icmF icmF B277_10194 B277_10194 B277_10199 B277_10199 B277_10304 B277_10304 B277_11030 B277_11030 B277_11035 B277_11035 B277_12231 B277_12231 B277_12236 B277_12236 B277_12471 B277_12471 B277_12481 B277_12481 B277_12486 B277_12486 B277_12701 B277_12701 B277_12756 B277_12756 B277_12761 B277_12761 B277_12766 B277_12766 B277_12771 B277_12771 B277_12776 B277_12776 B277_12781 B277_12781 B277_12786 B277_12786 B277_12791 B277_12791 B277_12796 B277_12796 B277_13784 B277_13784 B277_13834 B277_13834 B277_14179 B277_14179 B277_14339 B277_14339 B277_14344 B277_14344 B277_14349 B277_14349 acpP acpP fabH fabH B277_14488 B277_14488 B277_14493 B277_14493 B277_14498 B277_14498 B277_14503 B277_14503 mce mce B277_14513 B277_14513 B277_14518 B277_14518 B277_14588 B277_14588 B277_14903 B277_14903 B277_14913 B277_14913 B277_14948 B277_14948 B277_15008 B277_15008 B277_15013 B277_15013 B277_15018 B277_15018 B277_15164 B277_15164 B277_15184 B277_15184 B277_15189 B277_15189 B277_15789 B277_15789 B277_16089 B277_16089 B277_16104 B277_16104
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
B277_00595COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (670 aa)
B277_01094COG1960 Acyl-CoA dehydrogenases. (647 aa)
B277_01099Phosphotransferase; COG3173 Predicted aminoglycoside phosphotransferase. (344 aa)
B277_01124COG0477 Permeases of the major facilitator superfamily. (472 aa)
B277_01129Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (458 aa)
B277_01134COG1309 Transcriptional regulator. (224 aa)
B277_01139COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (429 aa)
fabG3-ketoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (445 aa)
B277_01149COG2030 Acyl dehydratase. (281 aa)
B277_02239COG1960 Acyl-CoA dehydrogenases. (623 aa)
B277_02491COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (608 aa)
B277_02496COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (736 aa)
B277_02501LAO/AO transport system ATPase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family. (333 aa)
B277_02631COG1960 Acyl-CoA dehydrogenases. (320 aa)
B277_04040COG0777 Acetyl-CoA carboxylase beta subunit. (356 aa)
B277_04045COG0825 Acetyl-CoA carboxylase alpha subunit. (285 aa)
B277_04227COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (378 aa)
B277_042323-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase. (690 aa)
B277_04757COG1024 Enoyl-CoA hydratase/carnithine racemase. (159 aa)
B277_05264Pyruvate carboxylase; COG0511 Biotin carboxyl carrier protein. (72 aa)
B277_05578COG1960 Acyl-CoA dehydrogenases. (384 aa)
B277_05953COG1024 Enoyl-CoA hydratase/carnithine racemase. (240 aa)
B277_06433Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (251 aa)
B277_07391COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit. (273 aa)
B277_07396COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit. (212 aa)
B277_08974COG1024 Enoyl-CoA hydratase/carnithine racemase. (240 aa)
B277_09177Biotin carboxyl carrier protein; COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit; biotin carboxylase. (588 aa)
B277_09217COG1960 Acyl-CoA dehydrogenases. (398 aa)
B277_09222COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (520 aa)
B277_09287COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (546 aa)
B277_09292COG0340 Biotin-(acetyl-CoA carboxylase) ligase. (238 aa)
B277_09682Glyoxalase/bleomycin resistance protein/dioxygenase. (145 aa)
B277_09747COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH). (251 aa)
B277_097523-oxoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (236 aa)
icmFmethylmalonyl-CoA mutase large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1083 aa)
B277_10194COG1960 Acyl-CoA dehydrogenases. (421 aa)
B277_10199COG1960 Acyl-CoA dehydrogenases. (433 aa)
B277_103043-hydroxyisobutyryl-CoA hydrolase; COG1024 Enoyl-CoA hydratase/carnithine racemase. (343 aa)
B277_11030COG2086 Electron transfer flavoprotein, beta subunit. (259 aa)
B277_11035COG2025 Electron transfer flavoprotein, alpha subunit. (313 aa)
B277_12231N-acetyltransferase GCN5; COG0456 Acetyltransferases. (363 aa)
B277_12236Putative enoyl-CoA hydratase/isomerase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (269 aa)
B277_12471COG1960 Acyl-CoA dehydrogenases. (250 aa)
B277_12481COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. (289 aa)
B277_12486HpcH/HpaI aldolase; COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. (356 aa)
B277_12701COG1024 Enoyl-CoA hydratase/carnithine racemase. (114 aa)
B277_12756Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (184 aa)
B277_12761Putative short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (268 aa)
B277_12766AMP-dependent synthetase/ligase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (508 aa)
B277_12771COG1960 Acyl-CoA dehydrogenases. (405 aa)
B277_12776COG1960 Acyl-CoA dehydrogenases. (389 aa)
B277_12781COG1960 Acyl-CoA dehydrogenases. (358 aa)
B277_12786COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
B277_12791Carbamoyl-phosphate synthase L chain ATP-binding protein; COG0439 Biotin carboxylase; overlaps another CDS with the same product name. (748 aa)
B277_12796Carbamoyl-phosphate synthase L chain ATP-binding protein; COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); overlaps another CDS with the same product name. (535 aa)
B277_137842,4-dienoyl-CoA reductase (NADPH); COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (76 aa)
B277_13834Succinate CoA transferase; COG0427 Acetyl-CoA hydrolase. (504 aa)
B277_14179hydroxymethylglutaryl-CoA lyase; COG0119 Isopropylmalate/homocitrate/citramalate synthases. (312 aa)
B277_14339COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (489 aa)
B277_14344Beta-ketoacyl synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (101 aa)
B277_14349COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (339 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (83 aa)
fabH3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (332 aa)
B277_14488COG1250 3-hydroxyacyl-CoA dehydrogenase. (286 aa)
B277_14493COG1960 Acyl-CoA dehydrogenases. (399 aa)
B277_14498COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; overlaps another CDS with the same product name. (241 aa)
B277_14503COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; overlaps another CDS with the same product name. (308 aa)
mcemethylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases. (143 aa)
B277_14513COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
B277_14518LAO/AO transport system ATPase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family. (320 aa)
B277_14588COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (259 aa)
B277_14903COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (261 aa)
B277_14913Dehydratase; COG2030 Acyl dehydratase. (350 aa)
B277_14948COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (245 aa)
B277_15008L-carnitine dehydratase/bile acid-inducible protein F; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family. (280 aa)
B277_15013NAD-binding protein 3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (724 aa)
B277_15018COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
B277_15164Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (271 aa)
B277_15184COG1024 Enoyl-CoA hydratase/carnithine racemase. (249 aa)
B277_15189COG0183 Acetyl-CoA acetyltransferase. (110 aa)
B277_15789COG2091 Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (231 aa)
B277_16089COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (733 aa)
B277_16104COG1250 3-hydroxyacyl-CoA dehydrogenase. (402 aa)
Your Current Organism:
Janibacter hoylei
NCBI taxonomy Id: 1210046
Other names: J. hoylei PVAS-1, Janibacter hoylei DSM 21601, Janibacter hoylei MTCC 8307, Janibacter hoylei PVAS-1, Janibacter hoylei str. PVAS-1, Janibacter hoylei strain PVAS-1, Janibacter sp. PVAS-1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.