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| | B277_03675 | Fumarylacetoacetase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (392 aa) |
| | B277_00250 | Putative oxidoreductase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (307 aa) |
| | hutG | Formimidoylglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family. (315 aa) |
| | hutU | Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (562 aa) |
| | acpS | 4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (117 aa) |
| | B277_00725 | Hypothetical protein; COG0406 Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family. (224 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (312 aa) |
| | B277_00955 | COG0277 FAD/FMN-containing dehydrogenases. (469 aa) |
| | B277_01094 | COG1960 Acyl-CoA dehydrogenases. (647 aa) |
| | B277_01139 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (429 aa) |
| | B277_01149 | COG2030 Acyl dehydratase. (281 aa) |
| | B277_01679 | Alcohol dehydrogenase zinc-binding domain protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (329 aa) |
| | B277_02044 | Hypothetical protein. (135 aa) |
| | B277_02049 | 2-dehydropantoate 2-reductase; COG1893 Ketopantoate reductase. (213 aa) |
| | B277_02194 | COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (413 aa) |
| | B277_02199 | COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (354 aa) |
| | B277_02204 | Hypothetical protein; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (456 aa) |
| | B277_02239 | COG1960 Acyl-CoA dehydrogenases. (623 aa) |
| | B277_02491 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (608 aa) |
| | B277_02631 | COG1960 Acyl-CoA dehydrogenases. (320 aa) |
| | B277_02778 | Hemerythrin HHE cation binding domain-containing protein. (185 aa) |
| | B277_03118 | Hypothetical protein; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (318 aa) |
| | B277_03258 | COG1960 Acyl-CoA dehydrogenases. (557 aa) |
| | B277_03380 | Long-chain fatty-acid--CoA ligase; COG1022 Long-chain acyl-CoA synthetases (AMP-forming). (618 aa) |
| | B277_03700 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (406 aa) |
| | B277_03770 | AMP-dependent synthetase/ligase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (514 aa) |
| | B277_04040 | COG0777 Acetyl-CoA carboxylase beta subunit. (356 aa) |
| | B277_04045 | COG0825 Acetyl-CoA carboxylase alpha subunit. (285 aa) |
| | B277_04227 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (378 aa) |
| | B277_04232 | 3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase. (690 aa) |
| | B277_04457 | COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (386 aa) |
| | B277_04722 | Alcohol dehydrogenase zinc-binding domain-containing protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (330 aa) |
| | B277_04757 | COG1024 Enoyl-CoA hydratase/carnithine racemase. (159 aa) |
| | B277_05094 | COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin. (345 aa) |
| | B277_05264 | Pyruvate carboxylase; COG0511 Biotin carboxyl carrier protein. (72 aa) |
| | B277_05578 | COG1960 Acyl-CoA dehydrogenases. (384 aa) |
| | B277_05953 | COG1024 Enoyl-CoA hydratase/carnithine racemase. (240 aa) |
| | B277_06724 | COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (521 aa) |
| | B277_06784 | Hydrolase; COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold. (500 aa) |
| | B277_06934 | COG2364 Predicted membrane protein. (237 aa) |
| | B277_06964 | COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (400 aa) |
| | gnd | COG1023 Predicted 6-phosphogluconate dehydrogenase. (361 aa) |
| | ectC | L-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (129 aa) |
| | ectB | Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa) |
| | B277_07376 | Hypothetical protein. (231 aa) |
| | acs | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (643 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (353 aa) |
| | B277_07638 | COG0491 Zn-dependent hydrolases, including glyoxylases. (270 aa) |
| | B277_07643 | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (281 aa) |
| | B277_07875 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (344 aa) |
| | B277_07930 | Putative fatty-acid--CoA ligase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (529 aa) |
| | B277_08539 | Malate dehydrogenase; COG0281 Malic enzyme. (491 aa) |
| | B277_08669 | Hypothetical protein; COG2513 PEP phosphonomutase and related enzymes. (263 aa) |
| | B277_08789 | Hydrolase; COG0491 Zn-dependent hydrolases, including glyoxylases. (308 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (175 aa) |
| | ispD | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (220 aa) |
| | gpmA | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (244 aa) |
| | B277_08974 | COG1024 Enoyl-CoA hydratase/carnithine racemase. (240 aa) |
| | B277_09217 | COG1960 Acyl-CoA dehydrogenases. (398 aa) |
| | B277_09222 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (520 aa) |
| | B277_09287 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (546 aa) |
| | B277_09407 | COG1228 Imidazolonepropionase and related amidohydrolases. (420 aa) |
| | B277_09747 | COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH). (251 aa) |
| | B277_09887 | COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. (538 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (263 aa) |
| | pgk | COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (402 aa) |
| | B277_10104 | Hypothetical protein. (310 aa) |
| | B277_10194 | COG1960 Acyl-CoA dehydrogenases. (421 aa) |
| | B277_10199 | COG1960 Acyl-CoA dehydrogenases. (433 aa) |
| | B277_10596 | COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (258 aa) |
| | B277_10760 | Oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. (338 aa) |
| | B277_10830 | Malic protein NAD-binding protein; COG0281 Malic enzyme. (386 aa) |
| | hutH | COG2986 Histidine ammonia-lyase. (518 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (350 aa) |
| | B277_11130 | COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (499 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (298 aa) |
| | coaBC | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (417 aa) |
| | B277_11890 | COG0469 Pyruvate kinase; overlaps another CDS with the same product name. (526 aa) |
| | B277_12216 | Alcohol dehydrogenase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (323 aa) |
| | B277_12261 | Pyruvate phosphate dikinase; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (899 aa) |
| | B277_12471 | COG1960 Acyl-CoA dehydrogenases. (250 aa) |
| | B277_12701 | COG1024 Enoyl-CoA hydratase/carnithine racemase. (114 aa) |
| | B277_12716 | COG1960 Acyl-CoA dehydrogenases. (408 aa) |
| | B277_12741 | Alcohol dehydrogenase zinc-binding domain-containing protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (317 aa) |
| | B277_12751 | Putative enoyl-CoA hydratase 1; COG2030 Acyl dehydratase (Nodulation protein) (N-related protein). (156 aa) |
| | B277_12766 | AMP-dependent synthetase/ligase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (508 aa) |
| | B277_12771 | COG1960 Acyl-CoA dehydrogenases. (405 aa) |
| | B277_12776 | COG1960 Acyl-CoA dehydrogenases. (389 aa) |
| | B277_12781 | COG1960 Acyl-CoA dehydrogenases. (358 aa) |
| | B277_12786 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa) |
| | B277_12791 | Carbamoyl-phosphate synthase L chain ATP-binding protein; COG0439 Biotin carboxylase; overlaps another CDS with the same product name. (748 aa) |
| | B277_12801 | COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (554 aa) |
| | B277_12841 | Hypothetical protein; COG2030 Acyl dehydratase; Belongs to the UPF0336 family. (148 aa) |
| | B277_12846 | MaoC domain-containing protein dehydratase; COG2030 Acyl dehydratase. (143 aa) |
| | B277_13124 | COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (325 aa) |
| | B277_13454 | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa) |
| | B277_13519 | Thioesterase superfamily protein; COG1607 Acyl-CoA hydrolase. (57 aa) |
| | B277_13524 | Thioesterase superfamily protein; COG1607 Acyl-CoA hydrolase. (106 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (393 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (385 aa) |
| | B277_13614 | AMP-binding domain protein; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (543 aa) |
| | B277_13834 | Succinate CoA transferase; COG0427 Acetyl-CoA hydrolase. (504 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (252 aa) |
| | B277_13949 | COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (616 aa) |
| | B277_14339 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (489 aa) |
| | B277_14344 | Beta-ketoacyl synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (101 aa) |
| | B277_14349 | COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (339 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (83 aa) |
| | fabH | 3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (332 aa) |
| | aceE | Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (930 aa) |
| | B277_14473 | Hypothetical protein. (208 aa) |
| | B277_14478 | Iron-sulfur cluster binding protein; COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain. (494 aa) |
| | B277_14488 | COG1250 3-hydroxyacyl-CoA dehydrogenase. (286 aa) |
| | B277_14493 | COG1960 Acyl-CoA dehydrogenases. (399 aa) |
| | B277_14498 | COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; overlaps another CDS with the same product name. (241 aa) |
| | B277_14503 | COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; overlaps another CDS with the same product name. (308 aa) |
| | B277_14513 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa) |
| | B277_14883 | Hypothetical protein. (233 aa) |
| | B277_14913 | Dehydratase; COG2030 Acyl dehydratase. (350 aa) |
| | B277_14933 | COG1960 Acyl-CoA dehydrogenases. (212 aa) |
| | B277_14948 | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (245 aa) |
| | B277_14953 | Pyrophosphate--fructose-6-phosphate 1-phosphotransferase; COG0205 6-phosphofructokinase. (402 aa) |
| | B277_15013 | NAD-binding protein 3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (724 aa) |
| | B277_15018 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa) |
| | B277_15184 | COG1024 Enoyl-CoA hydratase/carnithine racemase. (249 aa) |
| | B277_15189 | COG0183 Acetyl-CoA acetyltransferase. (110 aa) |
| | B277_15359 | COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (376 aa) |
| | B277_15374 | Amino acid adenylation enzyme/thioester reductase family protein. (56 aa) |
| | B277_15534 | AMP-dependent synthetase and ligase; COG1022 Long-chain acyl-CoA synthetases (AMP-forming). (596 aa) |
| | B277_15609 | long-chain-fatty-acid--CoA ligase; COG1022 Long-chain acyl-CoA synthetases (AMP-forming). (579 aa) |
| | B277_15842 | LPPG:FO 2-phospho-L-lactate transferase; COG0391 Uncharacterized conserved protein; overlaps another CDS with the same product name. (143 aa) |
| | B277_15847 | LPPG:FO 2-phospho-L-lactate transferase; COG0391 Uncharacterized conserved protein; overlaps another CDS with the same product name. (187 aa) |
| | B277_15852 | COG1960 Acyl-CoA dehydrogenases. (382 aa) |
| | B277_15912 | Amino acid adenylation enzyme/thioester reductase family protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins. (842 aa) |
| | panD | Aspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (148 aa) |
| | panC | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (302 aa) |
| | B277_16104 | COG1250 3-hydroxyacyl-CoA dehydrogenase. (402 aa) |
| | B277_16219 | Amino acid adenylation enzyme/thioester reductase family protein; COG0110 Acetyltransferase (isoleucine patch superfamily). (489 aa) |
| | B277_16242 | COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (152 aa) |
