STRINGSTRING
B277_12216 B277_12216 B277_12741 B277_12741 B277_07548 B277_07548 B277_12786 B277_12786 B277_12901 B277_12901 merA merA B277_13124 B277_13124 B277_13324 B277_13324 lpdA lpdA B277_14124 B277_14124 B277_14274 B277_14274 B277_14339 B277_14339 mce mce B277_14513 B277_14513 B277_07376 B277_07376 B277_06964 B277_06964 B277_06724 B277_06724 B277_05953 B277_05953 B277_05264 B277_05264 mmsA mmsA B277_04722 B277_04722 B277_04502 B277_04502 B277_04357 B277_04357 B277_04232 B277_04232 B277_04045 B277_04045 B277_04040 B277_04040 B277_03425 B277_03425 B277_02496 B277_02496 acs acs B277_07690 B277_07690 B277_09177 B277_09177 B277_09222 B277_09222 B277_09287 B277_09287 icmF icmF B277_14658 B277_14658 B277_14948 B277_14948 B277_15013 B277_15013 B277_15018 B277_15018 B277_15189 B277_15189 B277_16292 B277_16292 B277_16302 B277_16302 B277_16307 B277_16307 B277_02491 B277_02491 B277_01994 B277_01994 sucD sucD sucC sucC B277_01679 B277_01679 B277_01139 B277_01139 B277_01094 B277_01094 B277_00250 B277_00250 B277_10304 B277_10304 B277_10656 B277_10656 B277_11445 B277_11445
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
B277_12216Alcohol dehydrogenase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (323 aa)
B277_12741Alcohol dehydrogenase zinc-binding domain-containing protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (317 aa)
B277_07548Integrase catalytic subunit. (148 aa)
B277_12786COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
B277_12901Integrase catalytic subunit; COG2826 Transposase and inactivated derivatives, IS30 family. (63 aa)
merAMercuric reductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (466 aa)
B277_13124COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (325 aa)
B277_13324Mycothione reductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (474 aa)
lpdACOG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (462 aa)
B277_14124Integrase catalytic subunit. (88 aa)
B277_14274Transposase of ISAar43, IS3 family, IS407 group, orfB; COG2801 Transposase and inactivated derivatives. (168 aa)
B277_14339COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (489 aa)
mcemethylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases. (143 aa)
B277_14513COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
B277_07376Hypothetical protein. (231 aa)
B277_06964COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (400 aa)
B277_06724COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (521 aa)
B277_05953COG1024 Enoyl-CoA hydratase/carnithine racemase. (240 aa)
B277_05264Pyruvate carboxylase; COG0511 Biotin carboxyl carrier protein. (72 aa)
mmsACOG1012 NAD-dependent aldehyde dehydrogenases. (502 aa)
B277_04722Alcohol dehydrogenase zinc-binding domain-containing protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (330 aa)
B277_04502Hypothetical protein. (483 aa)
B277_04357CoA-binding protein; COG1042 Acyl-CoA synthetase (NDP forming). (636 aa)
B277_042323-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase. (690 aa)
B277_04045COG0825 Acetyl-CoA carboxylase alpha subunit. (285 aa)
B277_04040COG0777 Acetyl-CoA carboxylase beta subunit. (356 aa)
B277_03425COG2826 Transposase and inactivated derivatives, IS30 family. (292 aa)
B277_02496COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (736 aa)
acsacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (643 aa)
B277_07690COG2826 Transposase and inactivated derivatives, IS30 family. (70 aa)
B277_09177Biotin carboxyl carrier protein; COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit; biotin carboxylase. (588 aa)
B277_09222COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (520 aa)
B277_09287COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (546 aa)
icmFmethylmalonyl-CoA mutase large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1083 aa)
B277_14658Putative oxidoreductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (469 aa)
B277_14948COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (245 aa)
B277_15013NAD-binding protein 3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (724 aa)
B277_15018COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
B277_15189COG0183 Acetyl-CoA acetyltransferase. (110 aa)
B277_16292IS30 family transposase; COG2826 Transposase and inactivated derivatives, IS30 family. (161 aa)
B277_16302COG2826 Transposase and inactivated derivatives, IS30 family. (113 aa)
B277_16307Integrase catalytic subunit; COG2826 Transposase and inactivated derivatives, IS30 family. (355 aa)
B277_02491COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (608 aa)
B277_01994COG3564 Uncharacterized protein conserved in bacteria. (124 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (296 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (393 aa)
B277_01679Alcohol dehydrogenase zinc-binding domain protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (329 aa)
B277_01139COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (429 aa)
B277_01094COG1960 Acyl-CoA dehydrogenases. (647 aa)
B277_00250Putative oxidoreductase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (307 aa)
B277_103043-hydroxyisobutyryl-CoA hydrolase; COG1024 Enoyl-CoA hydratase/carnithine racemase. (343 aa)
B277_10656Alcohol dehydrogenase GroES domain-containing protein; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases. (393 aa)
B277_11445Peptidase S66 family protein; COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF. (345 aa)
Your Current Organism:
Janibacter hoylei
NCBI taxonomy Id: 1210046
Other names: J. hoylei PVAS-1, Janibacter hoylei DSM 21601, Janibacter hoylei MTCC 8307, Janibacter hoylei PVAS-1, Janibacter hoylei str. PVAS-1, Janibacter hoylei strain PVAS-1, Janibacter sp. PVAS-1
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