(54 nodes) Mixed, incl. RAB geranylgeranylation, and Exocyst network (Pediculus humanus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	E0V8Y0_PEDHC	GTP-binding nuclear protein RAN1, putative. (198 aa)
	E0V997_PEDHC	SET-binding factor, putative. (1980 aa)
	E0V9B4_PEDHC	RAB3A-interacting protein, putative. (404 aa)
	E0V9F9_PEDHC	Uncharacterized protein. (353 aa)
	E0VA21_PEDHC	Rab9 and, putative. (206 aa)
	E0VAI1_PEDHC	GTP-binding nuclear protein RAN1, putative. (210 aa)
	E0VAP8_PEDHC	Uncharacterized protein. (198 aa)
	E0VAT9_PEDHC	Rab-GAP TBC domain-containing protein. (468 aa)
	E0VAW6_PEDHC	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (294 aa)
	E0VAZ3_PEDHC	Myosin-5A, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1754 aa)
	E0VB02_PEDHC	Uncharacterized protein. (1229 aa)
	E0VBJ6_PEDHC	Rab5 GDP/GTP exchange factor, putative. (630 aa)
	E0VC34_PEDHC	Rab-GAP TBC domain-containing protein. (928 aa)
	E0VC51_PEDHC	Exocyst complex component sec3, putative. (858 aa)
	E0VC58_PEDHC	Uncharacterized protein. (222 aa)
	E0VC89_PEDHC	F-box/WD-repeat protein pof1, putative. (456 aa)
	E0VCC7_PEDHC	Rab6-interacting protein, putative. (1297 aa)
	E0VCG5_PEDHC	GTP-binding nuclear protein RAN1, putative. (218 aa)
	E0VCL9_PEDHC	Uncharacterized protein. (1467 aa)
	E0VCN7_PEDHC	GTP-binding nuclear protein RAN1, putative. (215 aa)
	E0VCT8_PEDHC	ADP-ribosylation factor-binding protein GGA1, putative. (654 aa)
	E0VCZ6_PEDHC	GTPase-activating protein gyp2, putative. (892 aa)
	E0VD18_PEDHC	GTP-binding nuclear protein RAN1, putative. (130 aa)
	E0VD21_PEDHC	Uncharacterized protein. (169 aa)
	E0VEQ8_PEDHC	Predicted protein. (215 aa)
	E0VFG0_PEDHC	Exocyst complex component, putative. (688 aa)
	E0VGZ3_PEDHC	Uncharacterized protein. (1550 aa)
	E0VI25_PEDHC	GTP-binding nuclear protein RAN1, putative. (78 aa)
	E0VIF6_PEDHC	FIP-RBD domain-containing protein. (480 aa)
	E0VIG2_PEDHC	Exocyst complex component, putative. (729 aa)
	E0VIX9_PEDHC	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (695 aa)
	E0VJ92_PEDHC	Ankyrin repeat and FYVE domain-containing protein, putative. (1122 aa)
	E0VKX1_PEDHC	Cytoplasmic linker protein, putative. (671 aa)
	E0VLH8_PEDHC	RAB GDP/GTP exchange factor, putative. (1381 aa)
	E0VN04_PEDHC	RAB-28, putative. (224 aa)
	E0VNA5_PEDHC	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (778 aa)
	E0VNS2_PEDHC	Ankyrin repeat-containing protein, putative. (885 aa)
	E0VQL4_PEDHC	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (846 aa)
	E0VR87_PEDHC	Tumor necrosis factor, alpha-induced protein, putative. (744 aa)
	E0VTD1_PEDHC	Rab6 GTPase activating protein, gapcena, putative. (1064 aa)
	E0VTH2_PEDHC	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. (534 aa)
	E0VTY1_PEDHC	GTP-binding protein YPT31/YPT8, putative. (207 aa)
	E0VUG8_PEDHC	Uncharacterized protein. (210 aa)
	E0VXN6_PEDHC	Osbpl1a, putative. (581 aa)
	E0VXN7_PEDHC	Oxysterol-binding protein; Belongs to the OSBP family. (441 aa)
	E0VY55_PEDHC	Rab-GAP TBC domain-containing protein. (417 aa)
	E0VYL8_PEDHC	Exocyst componenet sec8, putative. (939 aa)
	E0VYQ7_PEDHC	GTP-binding nuclear protein RAN1, putative. (211 aa)
	E0VZP2_PEDHC	Rab-GAP TBC domain-containing protein. (616 aa)
	E0W0Q0_PEDHC	Rab21, putative. (218 aa)
	E0W2C3_PEDHC	Geranylgeranyl transferase type-2 alpha subunit, putative. (556 aa)
	E0W3X4_PEDHC	Rab-GAP TBC domain-containing protein. (499 aa)
	E0W428_PEDHC	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (442 aa)
	E0W4H5_PEDHC	RAB geranylgeranyl transferase alpha subunit, putative. (89 aa)

Your Current Organism:

Pediculus humanus

NCBI taxonomy Id: 121224
Other names: P. humanus corporis, Pediculus humanus corporis, Pediculus humanus humanus, human body lice, human body louse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E0V8Y0_PEDHC	E0V9B4_PEDHC	E0V8Y0	E0V9B4	GTP-binding nuclear protein RAN1, putative.	RAB3A-interacting protein, putative.	0.630
E0V8Y0_PEDHC	E0VAI1_PEDHC	E0V8Y0	E0VAI1	GTP-binding nuclear protein RAN1, putative.	GTP-binding nuclear protein RAN1, putative.	0.425
E0V8Y0_PEDHC	E0VAW6_PEDHC	E0V8Y0	E0VAW6	GTP-binding nuclear protein RAN1, putative.	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.	0.478
E0V8Y0_PEDHC	E0VC51_PEDHC	E0V8Y0	E0VC51	GTP-binding nuclear protein RAN1, putative.	Exocyst complex component sec3, putative.	0.495
E0V8Y0_PEDHC	E0VFG0_PEDHC	E0V8Y0	E0VFG0	GTP-binding nuclear protein RAN1, putative.	Exocyst complex component, putative.	0.457
E0V8Y0_PEDHC	E0VIG2_PEDHC	E0V8Y0	E0VIG2	GTP-binding nuclear protein RAN1, putative.	Exocyst complex component, putative.	0.463
E0V8Y0_PEDHC	E0VIX9_PEDHC	E0V8Y0	E0VIX9	GTP-binding nuclear protein RAN1, putative.	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	0.486
E0V8Y0_PEDHC	E0VNA5_PEDHC	E0V8Y0	E0VNA5	GTP-binding nuclear protein RAN1, putative.	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	0.548
E0V8Y0_PEDHC	E0VQL4_PEDHC	E0V8Y0	E0VQL4	GTP-binding nuclear protein RAN1, putative.	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	0.492
E0V8Y0_PEDHC	E0VR87_PEDHC	E0V8Y0	E0VR87	GTP-binding nuclear protein RAN1, putative.	Tumor necrosis factor, alpha-induced protein, putative.	0.484
E0V8Y0_PEDHC	E0VTH2_PEDHC	E0V8Y0	E0VTH2	GTP-binding nuclear protein RAN1, putative.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.478
E0V8Y0_PEDHC	E0VYL8_PEDHC	E0V8Y0	E0VYL8	GTP-binding nuclear protein RAN1, putative.	Exocyst componenet sec8, putative.	0.502
E0V8Y0_PEDHC	E0VYQ7_PEDHC	E0V8Y0	E0VYQ7	GTP-binding nuclear protein RAN1, putative.	GTP-binding nuclear protein RAN1, putative.	0.434
E0V8Y0_PEDHC	E0W428_PEDHC	E0V8Y0	E0W428	GTP-binding nuclear protein RAN1, putative.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.624
E0V997_PEDHC	E0VTH2_PEDHC	E0V997	E0VTH2	SET-binding factor, putative.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.452
E0V997_PEDHC	E0W0Q0_PEDHC	E0V997	E0W0Q0	SET-binding factor, putative.	Rab21, putative.	0.604
E0V9B4_PEDHC	E0V8Y0_PEDHC	E0V9B4	E0V8Y0	RAB3A-interacting protein, putative.	GTP-binding nuclear protein RAN1, putative.	0.630
E0V9B4_PEDHC	E0V9F9_PEDHC	E0V9B4	E0V9F9	RAB3A-interacting protein, putative.	Uncharacterized protein.	0.630
E0V9B4_PEDHC	E0VA21_PEDHC	E0V9B4	E0VA21	RAB3A-interacting protein, putative.	Rab9 and, putative.	0.630
E0V9B4_PEDHC	E0VAP8_PEDHC	E0V9B4	E0VAP8	RAB3A-interacting protein, putative.	Uncharacterized protein.	0.929