(32 nodes) Post-transcriptional gene silencing network (Pediculus humanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	E0VBW2_PEDHC	Uncharacterized protein. (1199 aa)
	E0VB68_PEDHC	Translin, putative. (237 aa)
	E0W1B7_PEDHC	DRBM domain-containing protein. (652 aa)
	E0VAT3_PEDHC	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family. (579 aa)
	E0W0Y1_PEDHC	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family. (610 aa)
	E0W0Y0_PEDHC	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family. (755 aa)
	E0VYW5_PEDHC	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family. (675 aa)
	E0VY01_PEDHC	Arsenite-resistance protein, putative. (898 aa)
	E0VWX4_PEDHC	Uncharacterized protein. (764 aa)
	E0VWT2_PEDHC	Heat shock 70 kDa protein cognate 3 precursor,putative; Belongs to the heat shock protein 70 family. (656 aa)
	E0VWQ3_PEDHC	Uncharacterized protein. (443 aa)
	E0VWQ2_PEDHC	Pumilio, putative. (588 aa)
	E0VVP5_PEDHC	YEATS domain-containing protein, putative. (223 aa)
	E0VV93_PEDHC	Dicer-1, putative; Belongs to the helicase family. Dicer subfamily. (701 aa)
	E0VTT1_PEDHC	Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (382 aa)
	E0VTQ0_PEDHC	Dicer-1, putative; Belongs to the helicase family. Dicer subfamily. (2179 aa)
	E0VSP6_PEDHC	M_domain domain-containing protein. (1096 aa)
	E0VNV1_PEDHC	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family. (460 aa)
	E0VN41_PEDHC	Uncharacterized protein. (1519 aa)
	E0VN15_PEDHC	Uncharacterized protein. (448 aa)
	E0VLC0_PEDHC	Headcase domain-containing protein. (492 aa)
	E0VL41_PEDHC	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family. (678 aa)
	E0VJR6_PEDHC	WD_REPEATS_REGION domain-containing protein. (785 aa)
	E0VGG2_PEDHC	Helicase with zinc finger protein domain helz, putative. (1766 aa)
	E0VAL1_PEDHC	Tr-type G domain-containing protein. (411 aa)
	E0V954_PEDHC	Protein argonaute-2, putative; Belongs to the argonaute family. (1219 aa)
	E0W4C3_PEDHC	Eukaryotic translation initiation factor 2C, putative; Belongs to the argonaute family. (902 aa)
	E0W3Q3_PEDHC	Uncharacterized protein. (211 aa)
	E0W1H6_PEDHC	5'-3' exoribonuclease 1. (1587 aa)
	E0VG66_PEDHC	PAZ domain-containing protein. (132 aa)
	E0VG65_PEDHC	Dicer-1, putative. (471 aa)
	E0VFV2_PEDHC	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family. (684 aa)

Your Current Organism:

Pediculus humanus

NCBI taxonomy Id: 121224
Other names: P. humanus corporis, Pediculus humanus corporis, Pediculus humanus humanus, human body lice, human body louse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E0V954_PEDHC	E0VB68_PEDHC	E0V954	E0VB68	Protein argonaute-2, putative; Belongs to the argonaute family.	Translin, putative.	0.691
E0V954_PEDHC	E0VG65_PEDHC	E0V954	E0VG65	Protein argonaute-2, putative; Belongs to the argonaute family.	Dicer-1, putative.	0.698
E0V954_PEDHC	E0VG66_PEDHC	E0V954	E0VG66	Protein argonaute-2, putative; Belongs to the argonaute family.	PAZ domain-containing protein.	0.698
E0V954_PEDHC	E0VNV1_PEDHC	E0V954	E0VNV1	Protein argonaute-2, putative; Belongs to the argonaute family.	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	0.597
E0V954_PEDHC	E0VSP6_PEDHC	E0V954	E0VSP6	Protein argonaute-2, putative; Belongs to the argonaute family.	M_domain domain-containing protein.	0.881
E0V954_PEDHC	E0VTQ0_PEDHC	E0V954	E0VTQ0	Protein argonaute-2, putative; Belongs to the argonaute family.	Dicer-1, putative; Belongs to the helicase family. Dicer subfamily.	0.698
E0V954_PEDHC	E0VV93_PEDHC	E0V954	E0VV93	Protein argonaute-2, putative; Belongs to the argonaute family.	Dicer-1, putative; Belongs to the helicase family. Dicer subfamily.	0.698
E0V954_PEDHC	E0W1H6_PEDHC	E0V954	E0W1H6	Protein argonaute-2, putative; Belongs to the argonaute family.	5'-3' exoribonuclease 1.	0.434
E0V954_PEDHC	E0W4C3_PEDHC	E0V954	E0W4C3	Protein argonaute-2, putative; Belongs to the argonaute family.	Eukaryotic translation initiation factor 2C, putative; Belongs to the argonaute family.	0.424
E0VAL1_PEDHC	E0VTT1_PEDHC	E0VAL1	E0VTT1	Tr-type G domain-containing protein.	Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.	0.993
E0VAL1_PEDHC	E0W1H6_PEDHC	E0VAL1	E0W1H6	Tr-type G domain-containing protein.	5'-3' exoribonuclease 1.	0.628
E0VAT3_PEDHC	E0VFV2_PEDHC	E0VAT3	E0VFV2	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	0.445
E0VB68_PEDHC	E0V954_PEDHC	E0VB68	E0V954	Translin, putative.	Protein argonaute-2, putative; Belongs to the argonaute family.	0.691
E0VB68_PEDHC	E0W4C3_PEDHC	E0VB68	E0W4C3	Translin, putative.	Eukaryotic translation initiation factor 2C, putative; Belongs to the argonaute family.	0.743
E0VFV2_PEDHC	E0VAT3_PEDHC	E0VFV2	E0VAT3	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	0.445
E0VFV2_PEDHC	E0VL41_PEDHC	E0VFV2	E0VL41	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	0.454
E0VFV2_PEDHC	E0VNV1_PEDHC	E0VFV2	E0VNV1	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	0.667
E0VFV2_PEDHC	E0VYW5_PEDHC	E0VFV2	E0VYW5	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	0.455
E0VFV2_PEDHC	E0W0Y0_PEDHC	E0VFV2	E0W0Y0	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	0.461
E0VFV2_PEDHC	E0W0Y1_PEDHC	E0VFV2	E0W0Y1	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	0.457