(78 nodes) Innate immune response network (Pediculus humanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	E0VWB3_PEDHC	Neuroglian precursor, putative. (1253 aa)
	E0VWG3_PEDHC	Toll, putative. (1317 aa)
	E0VWZ8_PEDHC	Dual specificity mitogen-activated protein kinase kinase, putative. (772 aa)
	E0VT85_PEDHC	Caspase-3 precursor, putative; Belongs to the peptidase C14A family. (467 aa)
	E0VTA5_PEDHC	DUF3456 domain-containing protein. (209 aa)
	E0VTL8_PEDHC	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (379 aa)
	E0VJR7_PEDHC	Reelin domain-containing protein. (164 aa)
	E0VIL1_PEDHC	Predicted protein. (126 aa)
	E0VHV9_PEDHC	Tyrosine-protein kinase pr2, putative; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1156 aa)
	E0VHV8_PEDHC	Uncharacterized protein. (557 aa)
	E0VH58_PEDHC	Uncharacterized protein. (431 aa)
	E0VH22_PEDHC	Uncharacterized protein. (599 aa)
	E0VX77_PEDHC	Cyclin-dependent kinase 5 activator. (419 aa)
	E0VXB6_PEDHC	Poly [ADP-ribose] polymerase. (992 aa)
	E0VXY7_PEDHC	Tyrosine-protein kinase. (751 aa)
	E0VYT1_PEDHC	Protein kinase domain-containing protein. (744 aa)
	E0VZB7_PEDHC	PB1 domain-containing protein. (98 aa)
	E0VGX3_PEDHC	Serine-threonine protein kinase, plant-type, putative; Belongs to the protein kinase superfamily. (485 aa)
	E0VGQ2_PEDHC	Spaetzle domain-containing protein. (438 aa)
	E0VG83_PEDHC	Hect E3 ubiquitin ligase, putative. (1044 aa)
	E0VE99_PEDHC	Uncharacterized protein. (411 aa)
	E0VE35_PEDHC	Mitogen-activated protein kinase. (436 aa)
	E0VDL6_PEDHC	Transcription factor COE1, putative. (657 aa)
	E0W380_PEDHC	Spaetzle domain-containing protein. (287 aa)
	E0W357_PEDHC	GTPase_rho, putative. (249 aa)
	E0W2P4_PEDHC	Spaetzle domain-containing protein. (463 aa)
	E0W2M5_PEDHC	Defensin-2 precursor, putative. (113 aa)
	E0W210_PEDHC	Peptidoglycan recognition protein, putative. (546 aa)
	E0W1P9_PEDHC	Suppressor of potassium transport defect, putative. (682 aa)
	E0W1M6_PEDHC	Uncharacterized protein. (269 aa)
	E0W1E4_PEDHC	Ephrin type-B receptor 2 precursor, putative. (949 aa)
	E0W1C4_PEDHC	Caspase-8, putative; Belongs to the peptidase C14A family. (523 aa)
	E0W126_PEDHC	Guanine nucleotide exchange factor, putative. (1020 aa)
	E0VZP6_PEDHC	Laminin A chain, putative. (3650 aa)
	E0VZM0_PEDHC	Myeloid differentiation primary response protein MyD88, putative. (461 aa)
	E0VZL2_PEDHC	GTPase_rho, putative. (218 aa)
	E0VZH4_PEDHC	Embryonic polarity dorsal, putative. (793 aa)
	E0VZB9_PEDHC	Protein kinase C; Belongs to the protein kinase superfamily. (456 aa)
	E0VCL5_PEDHC	Ephrin-B1 precursor, putative; Belongs to the ephrin family. (241 aa)
	E0VCK3_PEDHC	Uncharacterized protein. (744 aa)
	E0VBY4_PEDHC	Ecsit, putative. (405 aa)
	E0VBI6_PEDHC	Dynein heavy chain, cytosolic, putative. (4516 aa)
	E0VBC4_PEDHC	Spaetzle domain-containing protein. (812 aa)
	E0VAV1_PEDHC	WD-repeat protein, putative. (813 aa)
	E0VA13_PEDHC	Rhogtpase, putative. (760 aa)
	E0V9C3_PEDHC	Uncharacterized protein. (260 aa)
	E0V999_PEDHC	Receptor protein-tyrosine kinase. (1312 aa)
	E0V954_PEDHC	Protein argonaute-2, putative; Belongs to the argonaute family. (1219 aa)
	E0VJ79_PEDHC	TPR repeat-containing protein R13F6.10, putative. (951 aa)
	E0VIY9_PEDHC	Protein pellino, putative. (413 aa)
	E0VIX7_PEDHC	Uncharacterized protein. (262 aa)
	E0VK42_PEDHC	Ral, putative. (202 aa)
	E0VK74_PEDHC	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1007 aa)
	E0VKB1_PEDHC	Tyrosine-protein kinase. (850 aa)
	E0VKU8_PEDHC	Collybistin, putative. (687 aa)
	E0VKV5_PEDHC	Methionine-R-sulfoxide reductase, putative. (93 aa)
	E0VLL9_PEDHC	Ovostatin precursor, putative. (1523 aa)
	E0VLM1_PEDHC	Uncharacterized protein. (1690 aa)
	E0VM96_PEDHC	Tyrosine-protein kinase. (493 aa)
	E0VMH5_PEDHC	GTPase_rho, putative. (229 aa)
	E0VN96_PEDHC	Spaetzle domain-containing protein. (490 aa)
	E0VNS7_PEDHC	RAC GTPase, putative. (192 aa)
	E0VPU4_PEDHC	Defensin precursor, putative. (109 aa)
	E0VPZ1_PEDHC	Diaphanous, putative. (1051 aa)
	E0VQA1_PEDHC	Alpha-2-macroglobulin precursor, putative. (1474 aa)
	E0VQF2_PEDHC	RAC GTPase, putative. (199 aa)
	E0VQI9_PEDHC	Tyrosine-protein kinase. (466 aa)
	E0VQL4_PEDHC	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (846 aa)
	E0VQV3_PEDHC	Shc transforming protein, putative. (419 aa)
	E0VR26_PEDHC	Flotillin-2, putative; Belongs to the band 7/mec-2 family. Flotillin subfamily. (430 aa)
	E0VS00_PEDHC	Spaetzle domain-containing protein. (542 aa)
	E0VS19_PEDHC	Uncharacterized protein. (231 aa)
	E0VSX8_PEDHC	RAC GTPase, putative. (191 aa)
	E0VU28_PEDHC	Hemocyte protein-glutamine gamma-glutamyltransferase, putative. (760 aa)
	E0VUB5_PEDHC	Flotillin-2, putative; Belongs to the band 7/mec-2 family. Flotillin subfamily. (495 aa)
	E0VV62_PEDHC	Protein vav, putative. (732 aa)
	E0VVX0_PEDHC	Uncharacterized protein. (678 aa)
	E0VVY6_PEDHC	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN, putative. (463 aa)

Your Current Organism:

Pediculus humanus

NCBI taxonomy Id: 121224
Other names: P. humanus corporis, Pediculus humanus corporis, Pediculus humanus humanus, human body lice, human body louse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E0V999_PEDHC	E0VK42_PEDHC	E0V999	E0VK42	Receptor protein-tyrosine kinase.	Ral, putative.	0.404
E0V999_PEDHC	E0VM96_PEDHC	E0V999	E0VM96	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase.	0.471
E0V999_PEDHC	E0VQI9_PEDHC	E0V999	E0VQI9	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase.	0.471
E0V999_PEDHC	E0VQV3_PEDHC	E0V999	E0VQV3	Receptor protein-tyrosine kinase.	Shc transforming protein, putative.	0.718
E0V999_PEDHC	E0VV62_PEDHC	E0V999	E0VV62	Receptor protein-tyrosine kinase.	Protein vav, putative.	0.453
E0V9C3_PEDHC	E0VBY4_PEDHC	E0V9C3	E0VBY4	Uncharacterized protein.	Ecsit, putative.	0.761
E0V9C3_PEDHC	E0VE99_PEDHC	E0V9C3	E0VE99	Uncharacterized protein.	Uncharacterized protein.	0.762
E0V9C3_PEDHC	E0VGX3_PEDHC	E0V9C3	E0VGX3	Uncharacterized protein.	Serine-threonine protein kinase, plant-type, putative; Belongs to the protein kinase superfamily.	0.844
E0V9C3_PEDHC	E0VIY9_PEDHC	E0V9C3	E0VIY9	Uncharacterized protein.	Protein pellino, putative.	0.676
E0V9C3_PEDHC	E0VYT1_PEDHC	E0V9C3	E0VYT1	Uncharacterized protein.	Protein kinase domain-containing protein.	0.771
E0V9C3_PEDHC	E0VZM0_PEDHC	E0V9C3	E0VZM0	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88, putative.	0.859
E0VA13_PEDHC	E0VE35_PEDHC	E0VA13	E0VE35	Rhogtpase, putative.	Mitogen-activated protein kinase.	0.469
E0VA13_PEDHC	E0VKU8_PEDHC	E0VA13	E0VKU8	Rhogtpase, putative.	Collybistin, putative.	0.595
E0VA13_PEDHC	E0VPZ1_PEDHC	E0VA13	E0VPZ1	Rhogtpase, putative.	Diaphanous, putative.	0.737
E0VA13_PEDHC	E0VV62_PEDHC	E0VA13	E0VV62	Rhogtpase, putative.	Protein vav, putative.	0.528
E0VBC4_PEDHC	E0VGQ2_PEDHC	E0VBC4	E0VGQ2	Spaetzle domain-containing protein.	Spaetzle domain-containing protein.	0.515
E0VBC4_PEDHC	E0VH58_PEDHC	E0VBC4	E0VH58	Spaetzle domain-containing protein.	Uncharacterized protein.	0.530
E0VBC4_PEDHC	E0VWG3_PEDHC	E0VBC4	E0VWG3	Spaetzle domain-containing protein.	Toll, putative.	0.552
E0VBY4_PEDHC	E0V9C3_PEDHC	E0VBY4	E0V9C3	Ecsit, putative.	Uncharacterized protein.	0.761
E0VBY4_PEDHC	E0VE99_PEDHC	E0VBY4	E0VE99	Ecsit, putative.	Uncharacterized protein.	0.922