STRINGSTRING
E0VPE3_PEDHC E0VPE3_PEDHC E0VRP4_PEDHC E0VRP4_PEDHC E0VU37_PEDHC E0VU37_PEDHC E0VP82_PEDHC E0VP82_PEDHC E0VEV6_PEDHC E0VEV6_PEDHC E0VVF4_PEDHC E0VVF4_PEDHC E0W3R6_PEDHC E0W3R6_PEDHC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
E0VPE3_PEDHCERCC4 domain-containing protein. (310 aa)
E0VRP4_PEDHCExonuclease, putative. (744 aa)
E0VU37_PEDHCDNA replication helicase DNA2, putative. (1157 aa)
E0VP82_PEDHCFlap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
E0VEV6_PEDHCFanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (718 aa)
E0VVF4_PEDHCDNA excision repair protein, putative. (1052 aa)
E0W3R6_PEDHCUncharacterized protein. (249 aa)
Your Current Organism:
Pediculus humanus
NCBI taxonomy Id: 121224
Other names: P. humanus corporis, Pediculus humanus corporis, Pediculus humanus humanus, human body lice, human body louse
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