STRINGSTRING
E0V914_PEDHC E0V914_PEDHC E0V992_PEDHC E0V992_PEDHC E0VA47_PEDHC E0VA47_PEDHC E0VDI9_PEDHC E0VDI9_PEDHC E0VEF2_PEDHC E0VEF2_PEDHC E0VG30_PEDHC E0VG30_PEDHC E0VG84_PEDHC E0VG84_PEDHC E0VGK6_PEDHC E0VGK6_PEDHC E0VJX4_PEDHC E0VJX4_PEDHC E0VM66_PEDHC E0VM66_PEDHC E0VP82_PEDHC E0VP82_PEDHC E0VPG0_PEDHC E0VPG0_PEDHC E0VPM2_PEDHC E0VPM2_PEDHC E0VQ67_PEDHC E0VQ67_PEDHC E0VSJ8_PEDHC E0VSJ8_PEDHC E0VSS9_PEDHC E0VSS9_PEDHC E0VST0_PEDHC E0VST0_PEDHC E0VUF8_PEDHC E0VUF8_PEDHC E0VUR3_PEDHC E0VUR3_PEDHC E0VW66_PEDHC E0VW66_PEDHC E0VWU9_PEDHC E0VWU9_PEDHC E0VXB6_PEDHC E0VXB6_PEDHC E0VZ83_PEDHC E0VZ83_PEDHC E0W111_PEDHC E0W111_PEDHC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
E0V914_PEDHCUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (286 aa)
E0V992_PEDHCHigh mobility group protein B2, putative. (187 aa)
E0VA47_PEDHCDNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (332 aa)
E0VDI9_PEDHCDNA polymerase epsilon subunit, putative. (192 aa)
E0VEF2_PEDHCDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (316 aa)
E0VG30_PEDHCENDO3c domain-containing protein. (168 aa)
E0VG84_PEDHCDNA ligase. (786 aa)
E0VGK6_PEDHCDNA ligase. (927 aa)
E0VJX4_PEDHCDNA-repair protein XRCC1, putative. (639 aa)
E0VM66_PEDHCG/t mismatch-specific thymine DNA glycosylase, putative. (1239 aa)
E0VP82_PEDHCFlap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
E0VPG0_PEDHCDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (440 aa)
E0VPM2_PEDHCDNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (524 aa)
E0VQ67_PEDHCProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
E0VSJ8_PEDHCDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2244 aa)
E0VSS9_PEDHCEndonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (292 aa)
E0VST0_PEDHCDNA-3-methyladenine glycosylase, putative. (276 aa)
E0VUF8_PEDHCSingle-strand selective monofunctional uracil DNA glycosylase, putative. (266 aa)
E0VUR3_PEDHCDNA polymerase. (1096 aa)
E0VW66_PEDHCDNA polymerase epsilon subunit, putative. (127 aa)
E0VWU9_PEDHC8-oxoguanine DNA glycosylase, putative. (323 aa)
E0VXB6_PEDHCPoly [ADP-ribose] polymerase. (992 aa)
E0VZ83_PEDHCDNA polymerase subunit delta, putative. (425 aa)
E0W111_PEDHCDNA polymerase delta small subunit, putative. (328 aa)
Your Current Organism:
Pediculus humanus
NCBI taxonomy Id: 121224
Other names: P. humanus corporis, Pediculus humanus corporis, Pediculus humanus humanus, human body lice, human body louse
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.