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ALV39793.1 ALV39793.1 ALV39801.1 ALV39801.1 ALV39906.1 ALV39906.1 ALV39907.1 ALV39907.1 ALV43686.1 ALV43686.1 ALV39920.1 ALV39920.1 ALV39945.1 ALV39945.1 ALV39954.1 ALV39954.1 ALV40021.1 ALV40021.1 acnA acnA ALV40202.1 ALV40202.1 ALV40453.1 ALV40453.1 aspA aspA ALV40510.1 ALV40510.1 ALV40511.1 ALV40511.1 ALV40512.1 ALV40512.1 ALV40513.1 ALV40513.1 AU252_04640 AU252_04640 ALV40588.1 ALV40588.1 ALV40705.1 ALV40705.1 sucD sucD sucC sucC ALV40855.1 ALV40855.1 pckG pckG ppc ppc ALV40968.1 ALV40968.1 ALV40969.1 ALV40969.1 ALV41188.1 ALV41188.1 ALV41621.1 ALV41621.1 ALV42078.1 ALV42078.1 ALV42079.1 ALV42079.1 ALV42349.1 ALV42349.1 ALV42485.1 ALV42485.1 gltA gltA mqo mqo
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALV39793.1Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
ALV39801.1Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
ALV39906.1Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
ALV39907.1Malate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (550 aa)
ALV43686.1NAD-dependent succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (492 aa)
ALV39920.1NAD-dependent succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (480 aa)
ALV39945.1NAD-dependent succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (494 aa)
ALV39954.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (246 aa)
ALV40021.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
acnAAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (936 aa)
ALV40202.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1131 aa)
ALV40453.1NAD-dependent succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (499 aa)
aspAClass II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (473 aa)
ALV40510.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa)
ALV40511.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
ALV40512.1Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (599 aa)
ALV40513.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (260 aa)
AU252_04640Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (739 aa)
ALV40588.1Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (262 aa)
ALV40705.1Tricarballylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
ALV40855.1FAD-linked oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (608 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (940 aa)
ALV40968.1Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
ALV40969.1Malate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (550 aa)
ALV41188.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
ALV41621.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
ALV42078.1Malate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (532 aa)
ALV42079.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
ALV42349.14-hydroxy-2-oxovalerate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (256 aa)
ALV42485.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (456 aa)
gltAType II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (427 aa)
mqoMalate:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
Your Current Organism:
Pseudarthrobacter sulfonivorans
NCBI taxonomy Id: 121292
Other names: ATCC BAA-112, Arthrobacter sp. ALL, Arthrobacter sulfonivorans, Arthrobacter sulfonivorans Borodina et al. 2002, DSM 14002, JCM 13520, P. sulfonivorans, Pseudarthrobacter sulfonivorans (Borodina et al. 2002) Busse 2016, strain ALL
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