STRINGSTRING
ALV39907.1 ALV39907.1 ALV39906.1 ALV39906.1 mqo mqo gltA gltA ALV40225.1 ALV40225.1 aspA aspA ALV40510.1 ALV40510.1 ALV40511.1 ALV40511.1 ALV40513.1 ALV40513.1 AU252_04640 AU252_04640 sucD sucD sucC sucC ppc ppc ALV40968.1 ALV40968.1 ALV40969.1 ALV40969.1 ALV41188.1 ALV41188.1 aspA-2 aspA-2 ALV42078.1 ALV42078.1 kgd kgd ALV40223.1 ALV40223.1 ALV40147.1 ALV40147.1 acnA acnA ALV39963.1 ALV39963.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALV39907.1Malate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (550 aa)
ALV39906.1Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
mqoMalate:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
gltAType II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (427 aa)
ALV40225.1Citrate synthase/methylcitrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
aspAClass II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (473 aa)
ALV40510.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa)
ALV40511.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
ALV40513.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (260 aa)
AU252_04640Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (739 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (940 aa)
ALV40968.1Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
ALV40969.1Malate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (550 aa)
ALV41188.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
aspA-2Class II fumarate hydratase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
ALV42078.1Malate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (532 aa)
kgdAlpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. (1266 aa)
ALV40223.12-methylcitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
ALV40147.1Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
acnAAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (936 aa)
ALV39963.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
Your Current Organism:
Pseudarthrobacter sulfonivorans
NCBI taxonomy Id: 121292
Other names: ATCC BAA-112, Arthrobacter sp. ALL, Arthrobacter sulfonivorans, Arthrobacter sulfonivorans Borodina et al. 2002, DSM 14002, JCM 13520, P. sulfonivorans, Pseudarthrobacter sulfonivorans (Borodina et al. 2002) Busse 2016, strain ALL
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