(48 nodes) Nucleosome, and PKMTs methylate histone lysines network (Colletotrichum fructicola)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CGGC5_14953	Uncharacterized protein. (234 aa)
	CGGC5_14603	Histone h3. (136 aa)
	CGGC5_14480	Uncharacterized protein. (151 aa)
	CGGC5_2049	Embryonic ectoderm development protein. (483 aa)
	CGGC5_13635	SET domain-containing protein. (413 aa)
	CGGC5_13410	Helo_like_N domain-containing protein. (280 aa)
	CGGC5_13258	Histone H2B; Belongs to the histone H2B family. (137 aa)
	CGGC5_13426	Set domain protein. (590 aa)
	CGGC5_13259	Histone H2A; Belongs to the histone H2A family. (134 aa)
	CGGC5_12398	Histone h1-binding protein. (511 aa)
	CGGC5_12414	DUF2236 domain-containing protein. (479 aa)
	CGGC5_1709	WD domain-containing protein. (476 aa)
	CGGC5_11877	Uncharacterized protein. (109 aa)
	CGGC5_12071	Rsc complex subunit. (581 aa)
	CGGC5_11143	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	CGGC5_11144	Histone H3; Belongs to the histone H3 family. (136 aa)
	CGGC5_11008	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (132 aa)
	CGGC5_10742	Set domain-containing protein. (1284 aa)
	CGGC5_10657	Chromobox protein/heterochromatin protein 1 beta-like protein. (384 aa)
	CGGC5_10576	Histone-lysine n-methyltransferase set9. (792 aa)
	CGGC5_10353	Uncharacterized protein. (642 aa)
	CGGC5_9936	Dpy-30 motif family protein. (168 aa)
	CGGC5_1147	Histone h1. (282 aa)
	CGGC5_9598	Chromo domain-containing protein. (620 aa)
	CGGC5_8425	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (481 aa)
	CGGC5_8032	Uncharacterized protein. (425 aa)
	CGGC5_7487	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (490 aa)
	CGGC5_7119	WD repeat-containing protein. (73 aa)
	CGGC5_824	Chromatin assembly factor 1 subunit. (438 aa)
	CGGC5_7025	Uncharacterized protein. (397 aa)
	CGGC5_6669	Uncharacterized protein. (68 aa)
	CGGC5_780	Tat pathway signal sequence. (495 aa)
	CGGC5_6684	Set domain protein. (338 aa)
	CGGC5_149	Ebs-bah-phd domain-containing protein. (459 aa)
	CGGC5_6670	Uncharacterized protein. (374 aa)
	CGGC5_6760	Set and ww domain protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (833 aa)
	CGGC5_6703	Uncharacterized protein. (491 aa)
	CGGC5_5182	Heterochromatin protein one. (270 aa)
	CGGC5_4881	Mynd finger family protein. (551 aa)
	CGGC5_5378	Phd finger domain-containing protein. (480 aa)
	CGGC5_321	Galactose-proton symport. (249 aa)
	CGGC5_3062	Grf zinc finger domain-containing protein. (429 aa)
	CGGC5_3700	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1270 aa)
	CGGC5_3112	Ash2-trithorax family protein. (561 aa)
	CGGC5_3211	Histone-lysine n-methyltransferase. (805 aa)
	CGGC5_2919	Duf1000 domain containing protein. (883 aa)
	CGGC5_2579	Jumonji family transcription. (1613 aa)
	CGGC5_2637	Histone H2A; Belongs to the histone H2A family. (141 aa)

Your Current Organism:

Colletotrichum fructicola

NCBI taxonomy Id: 1213859
Other names: C. fructicola Nara gc5, Colletotrichum fructicola Nara gc5

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CGGC5_10353	CGGC5_10576	L2FSY8	L2FS24	Uncharacterized protein.	Histone-lysine n-methyltransferase set9.	0.643
CGGC5_10353	CGGC5_10742	L2FSY8	L2FQR5	Uncharacterized protein.	Set domain-containing protein.	0.718
CGGC5_10353	CGGC5_11008	L2FSY8	L2FQC5	Uncharacterized protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.533
CGGC5_10353	CGGC5_11143	L2FSY8	L2FPP9	Uncharacterized protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.533
CGGC5_10353	CGGC5_11144	L2FSY8	L2FQ16	Uncharacterized protein.	Histone H3; Belongs to the histone H3 family.	0.514
CGGC5_10353	CGGC5_12414	L2FSY8	L2FKP8	Uncharacterized protein.	DUF2236 domain-containing protein.	0.514
CGGC5_10353	CGGC5_13426	L2FSY8	L2FI57	Uncharacterized protein.	Set domain protein.	0.423
CGGC5_10353	CGGC5_14603	L2FSY8	L2FBL3	Uncharacterized protein.	Histone h3.	0.514
CGGC5_10353	CGGC5_14953	L2FSY8	L2FB48	Uncharacterized protein.	Uncharacterized protein.	0.423
CGGC5_10353	CGGC5_1709	L2FSY8	L2FL65	Uncharacterized protein.	WD domain-containing protein.	0.601
CGGC5_10353	CGGC5_2637	L2FSY8	L2GIL5	Uncharacterized protein.	Histone H2A; Belongs to the histone H2A family.	0.567
CGGC5_10353	CGGC5_3062	L2FSY8	L2GFW3	Uncharacterized protein.	Grf zinc finger domain-containing protein.	0.514
CGGC5_10353	CGGC5_3112	L2FSY8	L2GG13	Uncharacterized protein.	Ash2-trithorax family protein.	0.527
CGGC5_10353	CGGC5_321	L2FSY8	L2GEP3	Uncharacterized protein.	Galactose-proton symport.	0.673
CGGC5_10353	CGGC5_3211	L2FSY8	L2GGF1	Uncharacterized protein.	Histone-lysine n-methyltransferase.	0.673
CGGC5_10353	CGGC5_3700	L2FSY8	L2GFX7	Uncharacterized protein.	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	0.593
CGGC5_10353	CGGC5_6669	L2FSY8	L2G413	Uncharacterized protein.	Uncharacterized protein.	0.423
CGGC5_10353	CGGC5_6670	L2FSY8	L2G4W7	Uncharacterized protein.	Uncharacterized protein.	0.423
CGGC5_10353	CGGC5_6684	L2FSY8	L2G423	Uncharacterized protein.	Set domain protein.	0.423
CGGC5_10353	CGGC5_6703	L2FSY8	L2G5Y2	Uncharacterized protein.	Uncharacterized protein.	0.504