(26 nodes) Mixed, incl. Nitrogen metabolism, and Regulation of nitrogen utilization network (Streptomyces collinus)

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Your Input:
	AGS67258.1	COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family. (527 aa)
	AGS67660.1	Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (362 aa)
	glsA	COG2066 Glutaminase; Belongs to the glutaminase family. (312 aa)
	AGS67898.1	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (264 aa)
	AGS68268.1	Hydantoinase/oxoprolinase; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit. (1212 aa)
	AGS68884.1	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. (495 aa)
	gltD	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. (487 aa)
	AGS68946.1	COG0067 Glutamate synthase domain 1. (1513 aa)
	AGS69125.1	COG0174 Glutamine synthetase. (469 aa)
	AGS69142.1	Glutamate--ammonia ligase; COG0174 Glutamine synthetase. (343 aa)
	AGS69178.1	COG0174 Glutamine synthetase. (453 aa)
	AGS69432.1	Ammonium transporter; COG0004 Ammonia permease. (437 aa)
	AGS69433.1	COG0347 Nitrogen regulatory protein PII. (112 aa)
	AGS69935.1	COG2902 NAD-specific glutamate dehydrogenase. (1645 aa)
	AGS72061.1	Ammonium transporter; COG0004 Ammonia permease. (427 aa)
	AGS72062.1	COG0347 Nitrogen regulatory protein PII. (112 aa)
	glnD	PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (816 aa)
	AGS72693.1	COG0405 Gamma-glutamyltransferase. (600 aa)
	AGS72711.1	COG0405 Gamma-glutamyltransferase. (601 aa)
	AGS72987.1	COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (392 aa)
	AGS73004.1	Hypothetical protein; COG4705 Uncharacterized membrane-anchored protein conserved in bacteria. (267 aa)
	AGS73005.1	COG1051 ADP-ribose pyrophosphatase. (175 aa)
	AGS73006.1	Hypothetical protein; COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold. (382 aa)
	AGS73007.1	COG0174 Glutamine synthetase. (467 aa)
	AGS73009.1	Hypothetical protein; COG0561 Predicted hydrolases of the HAD superfamily. (286 aa)
	AGS73437.1	COG0069 Glutamate synthase domain 2. (527 aa)

Your Current Organism:

Streptomyces collinus

NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGS67258.1	AGS68884.1	B446_02130	B446_10305	COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family.	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.	0.972
AGS67258.1	AGS68946.1	B446_02130	B446_10620	COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family.	COG0067 Glutamate synthase domain 1.	0.975
AGS67258.1	AGS72987.1	B446_02130	B446_30915	COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family.	COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.686
AGS67258.1	gltD	B446_02130	B446_10615	COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family.	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.	0.973
AGS67660.1	AGS68268.1	B446_04160	B446_07220	Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.	Hydantoinase/oxoprolinase; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit.	0.900
AGS67660.1	AGS68884.1	B446_04160	B446_10305	Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.	0.804
AGS67660.1	AGS68946.1	B446_04160	B446_10620	Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.	COG0067 Glutamate synthase domain 1.	0.800
AGS67660.1	AGS69125.1	B446_04160	B446_11515	Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.	COG0174 Glutamine synthetase.	0.800
AGS67660.1	AGS69142.1	B446_04160	B446_11600	Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.	Glutamate--ammonia ligase; COG0174 Glutamine synthetase.	0.800
AGS67660.1	AGS69178.1	B446_04160	B446_11780	Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.	COG0174 Glutamine synthetase.	0.800
AGS67660.1	AGS69935.1	B446_04160	B446_15585	Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.	COG2902 NAD-specific glutamate dehydrogenase.	0.800
AGS67660.1	AGS72693.1	B446_04160	B446_29435	Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.	COG0405 Gamma-glutamyltransferase.	0.931
AGS67660.1	AGS72711.1	B446_04160	B446_29525	Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.	COG0405 Gamma-glutamyltransferase.	0.931
AGS67660.1	AGS72987.1	B446_04160	B446_30915	Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.	COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.800
AGS67660.1	AGS73007.1	B446_04160	B446_31015	Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.	COG0174 Glutamine synthetase.	0.800
AGS67660.1	glsA	B446_04160	B446_05130	Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.	COG2066 Glutaminase; Belongs to the glutaminase family.	0.810
AGS67660.1	gltD	B446_04160	B446_10615	Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.	0.800
AGS67898.1	AGS68946.1	B446_05360	B446_10620	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	COG0067 Glutamate synthase domain 1.	0.704
AGS67898.1	AGS72987.1	B446_05360	B446_30915	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.925
AGS67898.1	glsA	B446_05360	B446_05130	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	COG2066 Glutaminase; Belongs to the glutaminase family.	0.924