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kirCII kirCII AGS68702.1 AGS68702.1 AGS68703.1 AGS68703.1 AGS69314.1 AGS69314.1 fabH fabH AGS69317.1 AGS69317.1 AGS69350.1 AGS69350.1 AGS69482.1 AGS69482.1 AGS69483.1 AGS69483.1 AGS69484.1 AGS69484.1 AGS69495.1 AGS69495.1 AGS69748.1 AGS69748.1 AGS71429.1 AGS71429.1 AGS71434.1 AGS71434.1 AGS71435.1 AGS71435.1 AGS71561.1 AGS71561.1 AGS71562.1 AGS71562.1 AGS71563.1 AGS71563.1 AGS71564.1 AGS71564.1 AGS72391.1 AGS72391.1 fabH-2 fabH-2 fabH-3 fabH-3 AGS73088.1 AGS73088.1
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
kirCIIAcyltransferase; COG3321 Polyketide synthase modules and related proteins; KirCII has specificity for ethylmalonyl-CoA, which is selectively transferred to ACP5 of KirAII. (445 aa)
AGS68702.1COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH). (255 aa)
AGS68703.13-oxoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (234 aa)
AGS69314.1COG0331 (acyl-carrier-protein) S-malonyltransferase. (310 aa)
fabH3-oxoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (351 aa)
AGS69317.13-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (420 aa)
AGS69350.1COG0777 Acetyl-CoA carboxylase beta subunit. (458 aa)
AGS69482.1Beta-ketoacyl synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (429 aa)
AGS69483.1Beta-ketoacyl synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (408 aa)
AGS69484.1COG0236 Acyl carrier protein. (87 aa)
AGS69495.1Putative secondary metabolite biosynthesis protein; COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III. (352 aa)
AGS69748.1COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit. (641 aa)
AGS71429.1COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit. (590 aa)
AGS71434.1COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (534 aa)
AGS71435.1Ligase; COG0340 Biotin-(acetyl-CoA carboxylase) ligase. (286 aa)
AGS71561.1COG0236 Acyl carrier protein. (87 aa)
AGS71562.13-oxoacyl-ACP synthase I; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (408 aa)
AGS71563.13-oxoacyl-ACP synthase I; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (364 aa)
AGS71564.13-oxoacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (247 aa)
AGS72391.13-oxoacyl-ACP synthase II; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (406 aa)
fabH-23-oxoacyl-ACP synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (335 aa)
fabH-33-oxoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (315 aa)
AGS73088.13-oxoacyl-ACP synthase III; COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III. (339 aa)
Your Current Organism:
Streptomyces collinus
NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365
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