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AGS68332.1 | Hydrolase; COG0637 Predicted phosphatase/phosphohexomutase. (491 aa) | ||||
nfo | Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (274 aa) | ||||
AGS70109.1 | COG0708 Exonuclease III. (264 aa) | ||||
nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (330 aa) | ||||
AGS70989.1 | COG1194 A/G-specific DNA glycosylase. (291 aa) |