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sucD sucD mdh mdh sdhB sdhB AGS71369.1 AGS71369.1 AGS71370.1 AGS71370.1 fumC fumC AGS71600.1 AGS71600.1 kgd kgd AGS72272.1 AGS72272.1 AGS72273.1 AGS72273.1 AGS72413.1 AGS72413.1 AGS72442.1 AGS72442.1 AGS72660.1 AGS72660.1 AGS73059.1 AGS73059.1 AGS73194.1 AGS73194.1 aspA aspA AGS69056.1 AGS69056.1 AGS69108.1 AGS69108.1 gltA gltA ppc ppc AGS70251.1 AGS70251.1 AGS70463.1 AGS70463.1 AGS71141.1 AGS71141.1 AGS71142.1 AGS71142.1 sucC sucC
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
sdhBCOG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (259 aa)
AGS71369.1COG2142 Succinate dehydrogenase, hydrophobic anchor subunit. (160 aa)
AGS71370.1COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. (126 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa)
AGS71600.1COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. (256 aa)
kgdAlpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. (1268 aa)
AGS72272.1COG0372 Citrate synthase. (423 aa)
AGS72273.1COG0372 Citrate synthase; Belongs to the citrate synthase family. (388 aa)
AGS72413.1COG2079 Uncharacterized protein involved in propionate catabolism. (522 aa)
AGS72442.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
AGS72660.1COG2225 Malate synthase; Belongs to the malate synthase family. (541 aa)
AGS73059.1COG2838 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (739 aa)
AGS73194.1COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. (249 aa)
aspACOG1027 Aspartate ammonia-lyase. (469 aa)
AGS69056.1Hypothetical protein; COG2129 Predicted phosphoesterases, related to the Icc protein. (251 aa)
AGS69108.1Dihydrolipoyllysine-residue succinyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (597 aa)
gltACOG0372 Citrate synthase; Belongs to the citrate synthase family. (429 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (910 aa)
AGS70251.1COG0372 Citrate synthase; Belongs to the citrate synthase family. (366 aa)
AGS70463.1Hydroxyglutarate oxidase; COG0579 Predicted dehydrogenase. (405 aa)
AGS71141.1COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (353 aa)
AGS71142.1COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. (642 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (393 aa)
Your Current Organism:
Streptomyces collinus
NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365
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