STRINGSTRING
AGS72469.1 AGS72469.1 AGS72541.1 AGS72541.1 AGS72610.1 AGS72610.1 AGS72651.1 AGS72651.1 AGS69463.1 AGS69463.1 AGS69118.1 AGS69118.1 ctaB ctaB AGS68827.1 AGS68827.1 AGS68746.1 AGS68746.1 AGS67616.1 AGS67616.1 AGS68078.1 AGS68078.1 AGS68423.1 AGS68423.1 AGS67973.1 AGS67973.1 hemC-2 hemC-2 AGS69656.1 AGS69656.1 AGS69902.1 AGS69902.1 hemA hemA hemC hemC AGS71022.1 AGS71022.1 AGS71024.1 AGS71024.1 hemL hemL hemH hemH hemE hemE AGS72468.1 AGS72468.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGS72469.1Hypothetical protein. (243 aa)
AGS72541.1Hypothetical protein. (246 aa)
AGS72610.1Hypothetical protein. (521 aa)
AGS72651.1COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain. (420 aa)
AGS69463.1Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (410 aa)
AGS69118.1Oxidoreductase; COG1233 Phytoene dehydrogenase and related proteins. (454 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (306 aa)
AGS68827.1COG1612 Uncharacterized protein required for cytochrome oxidase assembly. (336 aa)
AGS68746.1COG1239 Mg-chelatase subunit ChlI. (670 aa)
AGS67616.1Aminotransferase; COG0001 Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
AGS68078.1Hypothetical protein. (64 aa)
AGS68423.1uroporphyrin-III methyltransferase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); Belongs to the precorrin methyltransferase family. (409 aa)
AGS67973.1Hypothetical protein. (1224 aa)
hemC-2Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (311 aa)
AGS69656.1COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain. (448 aa)
AGS69902.1Bifunctional uroporphyrinogen-III synthetase/response regulator domain protein; COG1587 Uroporphyrinogen-III synthase. (387 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (566 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (303 aa)
AGS71022.1uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; COG0007 Uroporphyrinogen-III methylase. (569 aa)
AGS71024.1COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (310 aa)
hemLCOG0001 Glutamate-1-semialdehyde aminotransferase. (439 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (375 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (355 aa)
AGS72468.1Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (472 aa)
Your Current Organism:
Streptomyces collinus
NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365
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