STRINGSTRING
AGS71094.1 AGS71094.1 AGS71107.1 AGS71107.1 AGS71131.1 AGS71131.1 AGS71141.1 AGS71141.1 AGS71142.1 AGS71142.1 truA truA AGS71266.1 AGS71266.1 guaB guaB sucD sucD mdh mdh AGS71343.1 AGS71343.1 AGS71433.1 AGS71433.1 AGS71448.1 AGS71448.1 greA greA AGS71471.1 AGS71471.1 AGS71493.1 AGS71493.1 AGS71511.1 AGS71511.1 AGS71533.1 AGS71533.1 AGS71560.1 AGS71560.1 AGS71597.1 AGS71597.1 AGS71616.1 AGS71616.1 AGS71649.1 AGS71649.1 AGS71672.1 AGS71672.1 AGS71701.1 AGS71701.1 AGS71717.1 AGS71717.1 AGS71727.1 AGS71727.1 AGS71733.1 AGS71733.1 AGS71754.1 AGS71754.1 kgd kgd lysA lysA AGS71830.1 AGS71830.1 rho-2 rho-2 AGS71873.1 AGS71873.1 AGS71889.1 AGS71889.1 gatC gatC AGS71976.1 AGS71976.1 AGS71982.1 AGS71982.1 AGS71986.1 AGS71986.1 AGS72007.1 AGS72007.1 leuC leuC glnD glnD ispG1 ispG1 truB truB AGS72197.1 AGS72197.1 AGS72255.1 AGS72255.1 AGS72343.1 AGS72343.1 AGS72372.1 AGS72372.1 AGS72382.1 AGS72382.1 AGS72397.1 AGS72397.1 AGS72413.1 AGS72413.1 AGS72424.1 AGS72424.1 AGS72442.1 AGS72442.1 AGS72459.1 AGS72459.1 AGS72460.1 AGS72460.1 AGS72508.1 AGS72508.1 AGS72526.1 AGS72526.1 AGS72551.1 AGS72551.1 AGS72580.1 AGS72580.1 AGS72584.1 AGS72584.1 AGS72606.1 AGS72606.1 AGS72733.1 AGS72733.1 AGS72745.1 AGS72745.1 ispG2 ispG2 AGS72753.1 AGS72753.1 AGS72778.1 AGS72778.1 AGS72785.1 AGS72785.1 AGS72818.1 AGS72818.1 AGS72830.1 AGS72830.1 AGS72831.1 AGS72831.1 AGS72891.1 AGS72891.1 AGS72908.1 AGS72908.1 AGS72934.1 AGS72934.1 AGS72944.1 AGS72944.1 AGS72945.1 AGS72945.1 AGS72946.1 AGS72946.1 ispG3 ispG3 kbl kbl AGS70293.1 AGS70293.1 AGS73059.1 AGS73059.1 AGS73082.1 AGS73082.1 AGS73093.1 AGS73093.1 AGS73094.1 AGS73094.1 AGS73125.1 AGS73125.1 AGS73173.1 AGS73173.1 AGS73181.1 AGS73181.1 AGS73203.1 AGS73203.1 AGS73228.1 AGS73228.1 AGS73304.1 AGS73304.1 AGS73318.1 AGS73318.1 AGS73329.1 AGS73329.1 AGS73386.1 AGS73386.1 AGS73444.1 AGS73444.1 AGS73550.1 AGS73550.1 AGS73581.1 AGS73581.1 AGS73594.1 AGS73594.1 AGS73615.1 AGS73615.1 AGS73764.1 AGS73764.1 AGS73828.1 AGS73828.1 AGS73013.1 AGS73013.1 AGS70317.1 AGS70317.1 AGS70354.1 AGS70354.1 AGS70365.1 AGS70365.1 AGS70390.1 AGS70390.1 AGS70391.1 AGS70391.1 AGS70412.1 AGS70412.1 AGS70413.1 AGS70413.1 AGS70460.1 AGS70460.1 AGS70473.1 AGS70473.1 AGS70474.1 AGS70474.1 AGS70531.1 AGS70531.1 AGS70532.1 AGS70532.1 AGS70551.1 AGS70551.1 AGS70682.1 AGS70682.1 AGS70696.1 AGS70696.1 AGS70697.1 AGS70697.1 AGS70708.1 AGS70708.1 AGS70709.1 AGS70709.1 AGS70715.1 AGS70715.1 AGS70716.1 AGS70716.1 AGS70746.1 AGS70746.1 AGS70757.1 AGS70757.1 AGS70792.1 AGS70792.1 AGS70805.1 AGS70805.1 AGS70808.1 AGS70808.1 AGS70818.1 AGS70818.1 AGS70849.1 AGS70849.1 asd-2 asd-2 nth nth topA topA AGS70937.1 AGS70937.1 AGS70972.1 AGS70972.1 AGS71035.1 AGS71035.1 AGS71092.1 AGS71092.1 AGS67113.1 AGS67113.1 AGS67144.1 AGS67144.1 AGS67250.1 AGS67250.1 AGS67361.1 AGS67361.1 AGS67391.1 AGS67391.1 AGS67512.1 AGS67512.1 AGS67514.1 AGS67514.1 AGS67533.1 AGS67533.1 AGS67651.1 AGS67651.1 AGS67662.1 AGS67662.1 AGS67681.1 AGS67681.1 AGS67688.1 AGS67688.1 AGS67713.1 AGS67713.1 AGS67724.1 AGS67724.1 AGS67744.1 AGS67744.1 AGS67760.1 AGS67760.1 AGS67769.1 AGS67769.1 AGS67817.1 AGS67817.1 AGS67818.1 AGS67818.1 AGS67829.1 AGS67829.1 AGS67835.1 AGS67835.1 AGS67844.1 AGS67844.1 rho rho AGS67855.1 AGS67855.1 AGS67858.1 AGS67858.1 AGS67883.1 AGS67883.1 AGS67885.1 AGS67885.1 AGS67929.1 AGS67929.1 AGS67938.1 AGS67938.1 AGS67939.1 AGS67939.1 AGS67942.1 AGS67942.1 AGS67956.1 AGS67956.1 AGS67975.1 AGS67975.1 AGS67983.1 AGS67983.1 AGS67992.1 AGS67992.1 AGS67998.1 AGS67998.1 AGS68052.1 AGS68052.1 AGS68073.1 AGS68073.1 AGS68123.1 AGS68123.1 AGS68125.1 AGS68125.1 bioB bioB AGS68178.1 AGS68178.1 AGS68199.1 AGS68199.1 AGS68248.1 AGS68248.1 AGS68263.1 AGS68263.1 rbpA rbpA AGS68345.1 AGS68345.1 AGS68353.1 AGS68353.1 pyrR pyrR AGS68384.1 AGS68384.1 AGS68400.1 AGS68400.1 AGS68417.1 AGS68417.1 AGS68425.1 AGS68425.1 AGS68444.1 AGS68444.1 AGS68445.1 AGS68445.1 AGS68456.1 AGS68456.1 AGS68494.1 AGS68494.1 AGS68500.1 AGS68500.1 AGS68508.1 AGS68508.1 AGS68513.1 AGS68513.1 AGS68514.1 AGS68514.1 pafA pafA AGS68525.1 AGS68525.1 AGS68530.1 AGS68530.1 AGS68535.1 AGS68535.1 AGS68556.1 AGS68556.1 AGS68559.1 AGS68559.1 AGS68575.1 AGS68575.1 AGS68576.1 AGS68576.1 AGS68606.1 AGS68606.1 AGS68609.1 AGS68609.1 AGS68668.1 AGS68668.1 AGS68678.1 AGS68678.1 AGS68693.1 AGS68693.1 AGS68700.1 AGS68700.1 AGS68707.1 AGS68707.1 AGS68716.1 AGS68716.1 AGS68752.1 AGS68752.1 AGS68813.1 AGS68813.1 AGS68816.1 AGS68816.1 AGS68832.1 AGS68832.1 AGS68840.1 AGS68840.1 whiA whiA AGS68887.1 AGS68887.1 AGS68908.1 AGS68908.1 polA polA AGS68921.1 AGS68921.1 AGS68939.1 AGS68939.1 AGS68953.1 AGS68953.1 trpC trpC hisC hisC AGS69005.1 AGS69005.1 AGS69055.1 AGS69055.1 AGS69057.1 AGS69057.1 AGS69075.1 AGS69075.1 AGS69108.1 AGS69108.1 AGS69110.1 AGS69110.1 AGS69117.1 AGS69117.1 AGS69159.1 AGS69159.1 AGS69167.1 AGS69167.1 AGS69196.1 AGS69196.1 AGS69231.1 AGS69231.1 AGS69244.1 AGS69244.1 AGS69271.1 AGS69271.1 aceE aceE AGS69356.1 AGS69356.1 AGS69374.1 AGS69374.1 AGS69390.1 AGS69390.1 AGS69394.1 AGS69394.1 AGS69465.1 AGS69465.1 AGS69487.1 AGS69487.1 AGS69491.1 AGS69491.1 AGS69510.1 AGS69510.1 AGS69511.1 AGS69511.1 AGS69577.1 AGS69577.1 AGS69622.1 AGS69622.1 asd asd AGS69636.1 AGS69636.1 AGS69675.1 AGS69675.1 AGS69713.1 AGS69713.1 AGS69763.1 AGS69763.1 AGS69804.1 AGS69804.1 AGS69902.1 AGS69902.1 AGS69935.1 AGS69935.1 AGS69973.1 AGS69973.1 AGS70019.1 AGS70019.1 AGS70020.1 AGS70020.1 AGS70027.1 AGS70027.1 AGS70036.1 AGS70036.1 AGS70089.1 AGS70089.1 AGS70170.1 AGS70170.1 AGS70192.1 AGS70192.1 AGS70202.1 AGS70202.1 AGS70213.1 AGS70213.1 AGS70217.1 AGS70217.1 AGS70234.1 AGS70234.1 AGS70260.1 AGS70260.1 AGS70291.1 AGS70291.1 AGS66866.1 AGS66866.1 AGS66930.1 AGS66930.1 AGS67080.1 AGS67080.1 AGS67100.1 AGS67100.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AGS71094.1Regulatory protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (264 aa)
AGS71107.1Electron transfer oxidoreductase; COG0644 Dehydrogenases (flavoproteins). (427 aa)
AGS71131.1Isoprenyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (336 aa)
AGS71141.1COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (353 aa)
AGS71142.1COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. (642 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (283 aa)
AGS71266.1Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. (218 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (500 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
AGS71343.1Oxidoreductase; COG2303 Choline dehydrogenase and related flavoproteins. (510 aa)
AGS71433.1Hypothetical protein. (69 aa)
AGS71448.1Molecular chaperone GroES; COG1064 Zn-dependent alcohol dehydrogenases. (347 aa)
greATranscription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (166 aa)
AGS71471.1Dolichol-phosphate mannosyltransferase; COG0463 Glycosyltransferases involved in cell wall biogenesis. (394 aa)
AGS71493.1ATPase; COG0464 ATPases of the AAA+ class. (521 aa)
AGS71511.1COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins. (206 aa)
AGS71533.1Phague integrase; COG1961 Site-specific recombinases, DNA invertase Pin homologs. (522 aa)
AGS71560.1COG0031 Cysteine synthase. (338 aa)
AGS71597.1Hypothetical protein. (516 aa)
AGS71616.1SARP family transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (274 aa)
AGS71649.1COG4122 Predicted O-methyltransferase. (174 aa)
AGS71672.1COG0513 Superfamily II DNA and RNA helicases. (876 aa)
AGS71701.1ABC transporter ATP-binding protein; COG0661 Predicted unusual protein kinase. (465 aa)
AGS71717.1Hypothetical protein; COG0517 FOG: CBS domain. (131 aa)
AGS71727.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (227 aa)
AGS71733.1Terpene cyclase. (337 aa)
AGS71754.1TetR family transcriptional regulator; COG3226 Uncharacterized protein conserved in bacteria. (196 aa)
kgdAlpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. (1268 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (463 aa)
AGS71830.1COG0460 Homoserine dehydrogenase. (429 aa)
rho-2Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (670 aa)
AGS71873.1Acyltransferase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
AGS71889.1COG3118 Thioredoxin domain-containing protein. (323 aa)
gatCasparaginyl/glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (98 aa)
AGS71976.1Oxidoreductase; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases). (332 aa)
AGS71982.1COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
AGS71986.1COG0506 Proline dehydrogenase. (308 aa)
AGS72007.1Hypothetical protein. (61 aa)
leuCIsopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (474 aa)
glnDPII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (816 aa)
ispG14-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (385 aa)
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (301 aa)
AGS72197.1ATP-dependent DNA helicase; COG1201 Lhr-like helicases. (1668 aa)
AGS72255.1Sporulation transcription factor WhiH; COG2186 Transcriptional regulators. (288 aa)
AGS72343.1COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (602 aa)
AGS72372.1salicylyl-CoA 5-hydroxylase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. (778 aa)
AGS72382.1Regulatory protein; COG3629 DNA-binding transcriptional activator of the SARP family. (261 aa)
AGS72397.1Hypothetical protein; COG2867 Oligoketide cyclase/lipid transport protein. (160 aa)
AGS72413.1COG2079 Uncharacterized protein involved in propionate catabolism. (522 aa)
AGS72424.1COG0019 Diaminopimelate decarboxylase. (398 aa)
AGS72442.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
AGS72459.1Fatty acid oxidation complex alpha-subunit; COG1024 Enoyl-CoA hydratase/carnithine racemase. (709 aa)
AGS72460.1COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
AGS72508.1Germacradienol synthase. (720 aa)
AGS72526.1DsbA oxidoreductase. (214 aa)
AGS72551.1COG0155 Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (566 aa)
AGS72580.1COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (335 aa)
AGS72584.1ADA-like regulatory protein; COG2169 Adenosine deaminase. (472 aa)
AGS72606.1Hypothetical protein; COG1926 Predicted phosphoribosyltransferases. (216 aa)
AGS72733.1ADA-like regulatory protein; COG2169 Adenosine deaminase. (499 aa)
AGS72745.1Pentalenene synthase. (336 aa)
ispG24-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (433 aa)
AGS72753.1COG1929 Glycerate kinase; Belongs to the glycerate kinase type-1 family. (378 aa)
AGS72778.1Phenylacetic acid degradation protein PaaD; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme. (171 aa)
AGS72785.1COG0021 Transketolase. (615 aa)
AGS72818.1DNA-binding protein; COG1396 Predicted transcriptional regulators. (287 aa)
AGS72830.1Oxidoreductase; COG0656 Aldo/keto reductases, related to diketogulonate reductase. (278 aa)
AGS72831.1long-chain-fatty-acid-CoA ligase; COG1022 Long-chain acyl-CoA synthetases (AMP-forming). (608 aa)
AGS72891.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (691 aa)
AGS72908.1Alpha-glucosidase; COG0366 Glycosidases. (535 aa)
AGS72934.1acyl-ACP desaturase. (324 aa)
AGS72944.1Fatty acid-CoA racemase; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family. (394 aa)
AGS72945.1COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
AGS72946.1Fatty acid oxidative multifunctional enzyme; COG1024 Enoyl-CoA hydratase/carnithine racemase. (727 aa)
ispG34-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (371 aa)
kbl2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (399 aa)
AGS70293.1COG1061 DNA or RNA helicases of superfamily II. (549 aa)
AGS73059.1COG2838 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (739 aa)
AGS73082.1COG2186 Transcriptional regulators. (249 aa)
AGS73093.1DEAD/DEAH box helicase; COG0513 Superfamily II DNA and RNA helicases. (523 aa)
AGS73094.1COG0513 Superfamily II DNA and RNA helicases. (472 aa)
AGS73125.1Oxidoreductase; COG0656 Aldo/keto reductases, related to diketogulonate reductase. (281 aa)
AGS73173.1COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (287 aa)
AGS73181.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (156 aa)
AGS73203.1Hypothetical protein. (72 aa)
AGS73228.1COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase. (676 aa)
AGS73304.1Hypothetical protein. (149 aa)
AGS73318.1Sigma-70 region 2 domain-containing protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (182 aa)
AGS73329.1Hypothetical protein. (334 aa)
AGS73386.1COG1064 Zn-dependent alcohol dehydrogenases. (341 aa)
AGS73444.1COG0071 Molecular chaperone (small heat shock protein). (143 aa)
AGS73550.1COG0031 Cysteine synthase. (757 aa)
AGS73581.1COG0071 Molecular chaperone (small heat shock protein). (143 aa)
AGS73594.1COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (356 aa)
AGS73615.1COG3226 Uncharacterized protein conserved in bacteria. (185 aa)
AGS73764.1Orn/DAP/Arg decarboxylase 2; COG0019 Diaminopimelate decarboxylase. (434 aa)
AGS73828.1Recombinase; COG2801 Transposase and inactivated derivatives. (197 aa)
AGS73013.1beta-ketoadipyl-CoA thiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
AGS70317.1COG0380 Trehalose-6-phosphate synthase. (475 aa)
AGS70354.1Pyridoxamine 5'-phosphate oxidase. (134 aa)
AGS70365.1ANTAR domain-containing protein; COG2203 FOG: GAF domain. (285 aa)
AGS70390.1Hypothetical protein. (197 aa)
AGS70391.1DNA-binding protein; COG1396 Predicted transcriptional regulators. (163 aa)
AGS70412.1Hypothetical protein. (95 aa)
AGS70413.1COG2897 Rhodanese-related sulfurtransferase. (281 aa)
AGS70460.1COG3629 DNA-binding transcriptional activator of the SARP family. (1106 aa)
AGS70473.1COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases). (322 aa)
AGS70474.1COG0513 Superfamily II DNA and RNA helicases. (727 aa)
AGS70531.1Hypothetical protein; COG3707 Response regulator with putative antiterminator output domain. (234 aa)
AGS70532.1Hypothetical protein; COG2203 FOG: GAF domain. (205 aa)
AGS70551.1Lipid-transfer protein; COG0183 Acetyl-CoA acetyltransferase. (388 aa)
AGS70682.1Hypothetical protein; COG1716 FOG: FHA domain. (283 aa)
AGS70696.1COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (334 aa)
AGS70697.1Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (444 aa)
AGS70708.1COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (328 aa)
AGS70709.1Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (475 aa)
AGS70715.1Hypothetical protein. (274 aa)
AGS70716.1Hydrolase; COG0388 Predicted amidohydrolase. (264 aa)
AGS70746.1Sugar hydrolase; COG0366 Glycosidases. (548 aa)
AGS70757.1COG3222 Uncharacterized protein conserved in bacteria. (203 aa)
AGS70792.1Antibiotic biosynthesis monooxygenase; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides. (108 aa)
AGS70805.1Hypothetical protein. (137 aa)
AGS70808.1Aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (391 aa)
AGS70818.1Integrase/recombinase; COG1961 Site-specific recombinases, DNA invertase Pin homologs. (482 aa)
AGS70849.1COG0527 Aspartokinases; Belongs to the aspartokinase family. (423 aa)
asd-2Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (360 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (330 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (943 aa)
AGS70937.1DNA-binding protein. (240 aa)
AGS70972.1COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (325 aa)
AGS71035.1Hypothetical protein. (397 aa)
AGS71092.1Long-chain-fatty acid CoA ligase; COG1022 Long-chain acyl-CoA synthetases (AMP-forming). (652 aa)
AGS67113.1COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family. (143 aa)
AGS67144.1COG0031 Cysteine synthase. (757 aa)
AGS67250.1COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family. (143 aa)
AGS67361.1COG4829 Muconolactone delta-isomerase. (97 aa)
AGS67391.1Hypothetical protein; COG3707 Response regulator with putative antiterminator output domain. (228 aa)
AGS67512.1Flavoprotein; COG0277 FAD/FMN-containing dehydrogenases. (529 aa)
AGS67514.1COG0578 Glycerol-3-phosphate dehydrogenase. (525 aa)
AGS67533.1COG2188 Transcriptional regulators. (248 aa)
AGS67651.1Hypothetical protein. (142 aa)
AGS67662.1long-chain-fatty-acid-CoA ligase; COG1022 Long-chain acyl-CoA synthetases (AMP-forming). (634 aa)
AGS67681.1Lipoprotein; COG3786 Uncharacterized protein conserved in bacteria. (254 aa)
AGS67688.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (288 aa)
AGS67713.1Hypothetical protein. (350 aa)
AGS67724.1ABC transporter ATP-binding protein; COG1131 ABC-type multidrug transport system, ATPase component. (778 aa)
AGS67744.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (229 aa)
AGS67760.1Hypothetical protein; COG1066 Predicted ATP-dependent serine protease. (364 aa)
AGS67769.1COG0183 Acetyl-CoA acetyltransferase. (388 aa)
AGS67817.1COG1695 Predicted transcriptional regulators. (194 aa)
AGS67818.1COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (671 aa)
AGS67829.1Hypothetical protein. (70 aa)
AGS67835.1Sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (207 aa)
AGS67844.1COG1695 Predicted transcriptional regulators. (189 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (381 aa)
AGS67855.1L-asparagine operon repressor; COG2186 Transcriptional regulators. (242 aa)
AGS67858.1Hypothetical protein. (135 aa)
AGS67883.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (292 aa)
AGS67885.1COG1695 Predicted transcriptional regulators. (189 aa)
AGS67929.1COG0644 Dehydrogenases (flavoproteins). (413 aa)
AGS67938.1COG2025 Electron transfer flavoprotein, alpha subunit. (320 aa)
AGS67939.1COG2086 Electron transfer flavoprotein, beta subunit. (261 aa)
AGS67942.1Acyltransferase; COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase. (242 aa)
AGS67956.1NADPH-ferredoxin reductase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. (446 aa)
AGS67975.1Hypothetical protein. (140 aa)
AGS67983.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (301 aa)
AGS67992.1Lipoprotein; COG3786 Uncharacterized protein conserved in bacteria. (190 aa)
AGS67998.1COG4581 Superfamily II RNA helicase. (837 aa)
AGS68052.1COG0031 Cysteine synthase. (341 aa)
AGS68073.1Putative TetR family transcriptional regulator; COG1309 Transcriptional regulator. (211 aa)
AGS68123.1DNA-binding protein. (286 aa)
AGS68125.18-amino-7-oxononanoate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. (375 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (411 aa)
AGS68178.1COG0110 Acetyltransferase (isoleucine patch superfamily). (254 aa)
AGS68199.13-ketoacyl-CoA thiolase/acetyl-CoA acetyltransferase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
AGS68248.1Hypothetical protein. (157 aa)
AGS68263.1Lipid-transfer protein; COG0183 Acetyl-CoA acetyltransferase. (396 aa)
rbpAHypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. (124 aa)
AGS68345.1RNA-binding Sun protein; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (475 aa)
AGS68353.1COG0099 Ribosomal protein S13. (107 aa)
pyrRBifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (190 aa)
AGS68384.1(p)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (837 aa)
AGS68400.1COG0480 Translation elongation factors (GTPases). (704 aa)
AGS68417.1COG0147 Anthranilate/para-aminobenzoate synthases component I. (365 aa)
AGS68425.1precorrin-6Y C5,15-methyltransferase; COG2241 Precorrin-6B methylase 1. (408 aa)
AGS68444.1Hypothetical protein. (195 aa)
AGS68445.1COG3786 Uncharacterized protein conserved in bacteria. (234 aa)
AGS68456.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (188 aa)
AGS68494.1COG2186 Transcriptional regulators. (250 aa)
AGS68500.1COG0258 5'-3' exonuclease (including N-terminal domain of PolI). (301 aa)
AGS68508.1Helicase; COG4581 Superfamily II RNA helicase. (935 aa)
AGS68513.1Hypothetical protein; COG2378 Predicted transcriptional regulator. (345 aa)
AGS68514.1Hypothetical protein; COG2378 Predicted transcriptional regulator. (325 aa)
pafAProteasome component; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. (453 aa)
AGS68525.1Proteasome component. (503 aa)
AGS68530.1Peptidase; COG1994 Zn-dependent proteases. (566 aa)
AGS68535.15-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1156 aa)
AGS68556.1COG1926 Predicted phosphoribosyltransferases. (442 aa)
AGS68559.1COG2186 Transcriptional regulators. (233 aa)
AGS68575.1DNA-binding protein; COG2508 Regulator of polyketide synthase expression. (564 aa)
AGS68576.1Orn/DAP/Arg decarboxylase 2; COG0019 Diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (450 aa)
AGS68606.1COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family. (398 aa)
AGS68609.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa)
AGS68668.1DNA recombination and repair protein; May be involved in recombinational repair of damaged DNA. (580 aa)
AGS68678.1Hypothetical protein. (669 aa)
AGS68693.1ABC transporter ATP-binding protein; COG1131 ABC-type multidrug transport system, ATPase component. (842 aa)
AGS68700.1COG2186 Transcriptional regulators. (230 aa)
AGS68707.1Hypothetical protein; COG0312 Predicted Zn-dependent proteases and their inactivated homologs. (464 aa)
AGS68716.1Hypothetical protein; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family. (459 aa)
AGS68752.1precorrin-6Y C5,15-methyltransferase; COG2241 Precorrin-6B methylase 1. (413 aa)
AGS68813.1TetR family transcriptional regulator; COG3226 Uncharacterized protein conserved in bacteria. (177 aa)
AGS68816.1Hypothetical protein; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme. (110 aa)
AGS68832.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (695 aa)
AGS68840.1Trehalose-6-phosphate hydrolase; COG0366 Glycosidases. (544 aa)
whiAPutative sporulation transcription regulator whiA; Involved in cell division and chromosome segregation. (329 aa)
AGS68887.1DNA-binding protein; COG1396 Predicted transcriptional regulators. (286 aa)
AGS68908.1Hypothetical protein; COG2951 Membrane-bound lytic murein transglycosylase B. (576 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (908 aa)
AGS68921.1COG3707 Response regulator with putative antiterminator output domain. (217 aa)
AGS68939.1COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (385 aa)
AGS68953.1COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family. (406 aa)
trpCCOG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (269 aa)
hisCCOG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (368 aa)
AGS69005.1Multicopper polyphenol oxidase; Belongs to the multicopper oxidase YfiH/RL5 family. (235 aa)
AGS69055.1Hypothetical protein. (146 aa)
AGS69057.1COG1022 Long-chain acyl-CoA synthetases (AMP-forming). (598 aa)
AGS69075.1COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (133 aa)
AGS69108.1Dihydrolipoyllysine-residue succinyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (597 aa)
AGS69110.12-oxoacid dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (900 aa)
AGS69117.1NAD dependent epimerase/dehydratase family protein; COG1090 Predicted nucleoside-diphosphate sugar epimerase. (298 aa)
AGS69159.1Alpha-glucosidase; COG0366 Glycosidases. (561 aa)
AGS69167.1Secreted acid phosphatase. (295 aa)
AGS69196.1Multi-domain regulatory protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (1087 aa)
AGS69231.1COG1579 Zn-ribbon protein, possibly nucleic acid-binding. (273 aa)
AGS69244.1Lipid-transfer protein; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
AGS69271.1COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
aceEPyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (878 aa)
AGS69356.1Hypothetical protein; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (231 aa)
AGS69374.1COG1251 NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (869 aa)
AGS69390.1Oxidoreductase; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases). (336 aa)
AGS69394.1COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family. (322 aa)
AGS69465.1COG1022 Long-chain acyl-CoA synthetases (AMP-forming). (623 aa)
AGS69487.1Actinorhodin polyketide synthase bifunctional cyclase/dehydratase; COG2867 Oligoketide cyclase/lipid transport protein. (315 aa)
AGS69491.1Cyclase; COG2867 Oligoketide cyclase/lipid transport protein. (275 aa)
AGS69510.1Glucose-1-phosphate thymidylyltransferase; COG1209 dTDP-glucose pyrophosphorylase. (351 aa)
AGS69511.1COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (330 aa)
AGS69577.1Integrase. (102 aa)
AGS69622.1Hypothetical protein; COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase. (326 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (338 aa)
AGS69636.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (205 aa)
AGS69675.1COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (319 aa)
AGS69713.1Oxidoreductase; COG1064 Zn-dependent alcohol dehydrogenases. (347 aa)
AGS69763.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (175 aa)
AGS69804.1COG2186 Transcriptional regulators. (263 aa)
AGS69902.1Bifunctional uroporphyrinogen-III synthetase/response regulator domain protein; COG1587 Uroporphyrinogen-III synthase. (387 aa)
AGS69935.1COG2902 NAD-specific glutamate dehydrogenase. (1645 aa)
AGS69973.1Hypothetical protein; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. (336 aa)
AGS70019.1Hypothetical protein; COG2755 Lysophospholipase L1 and related esterases. (331 aa)
AGS70020.1COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
AGS70027.1COG2230 Cyclopropane fatty acid synthase and related methyltransferases. (429 aa)
AGS70036.1Nucleoside triphosphate pyrophosphohydrolase; COG1694 Predicted pyrophosphatase. (331 aa)
AGS70089.1COG0768 Cell division protein FtsI/penicillin-binding protein 2. (552 aa)
AGS70170.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa)
AGS70192.1Hypothetical protein. (135 aa)
AGS70202.1Lipid-transfer protein; COG0183 Acetyl-CoA acetyltransferase. (384 aa)
AGS70213.1Hypothetical protein; COG0183 Acetyl-CoA acetyltransferase. (390 aa)
AGS70217.1COG2072 Predicted flavoprotein involved in K+ transport. (392 aa)
AGS70234.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (200 aa)
AGS70260.1Hypothetical protein. (264 aa)
AGS70291.1Hypothetical protein. (845 aa)
AGS66866.1Recombinase; COG2801 Transposase and inactivated derivatives. (197 aa)
AGS66930.1Orn/DAP/Arg decarboxylase 2; COG0019 Diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (434 aa)
AGS67080.1COG3226 Uncharacterized protein conserved in bacteria. (185 aa)
AGS67100.1COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (356 aa)
Your Current Organism:
Streptomyces collinus
NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365
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