(100 nodes) Lipid catabolic process network (Streptomyces collinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AGS67344.1	Hypothetical protein; COG4188 Predicted dienelactone hydrolase. (289 aa)
	AGS67356.1	COG1960 Acyl-CoA dehydrogenases. (409 aa)
	AGS67457.1	Secreted hydrolase; COG0769 UDP-N-acetylmuramyl tripeptide synthase. (270 aa)
	AGS67461.1	Hypothetical protein. (274 aa)
	AGS67464.1	COG1960 Acyl-CoA dehydrogenases. (390 aa)
	AGS67465.1	COG1960 Acyl-CoA dehydrogenases. (390 aa)
	AGS67486.1	Secreted hydrolase. (293 aa)
	AGS67525.1	COG1960 Acyl-CoA dehydrogenases. (653 aa)
	AGS67579.1	Secreted hydrolase. (286 aa)
	AGS67684.1	FAD-binding dehydrogenase; COG3573 Predicted oxidoreductase. (557 aa)
	AGS67737.1	Hypothetical protein; COG1960 Acyl-CoA dehydrogenases. (366 aa)
	AGS67769.1	COG0183 Acetyl-CoA acetyltransferase. (388 aa)
	AGS67770.1	Lipid-transfer protein; COG0183 Acetyl-CoA acetyltransferase. (349 aa)
	AGS67771.1	Hypothetical protein; COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon. (313 aa)
	AGS67791.1	COG1960 Acyl-CoA dehydrogenases. (392 aa)
	AGS67884.1	COG1960 Acyl-CoA dehydrogenases. (574 aa)
	AGS67958.1	Oxidoreductase; COG1960 Acyl-CoA dehydrogenases. (559 aa)
	AGS68079.1	COG1960 Acyl-CoA dehydrogenases. (360 aa)
	AGS68080.1	COG1960 Acyl-CoA dehydrogenases. (393 aa)
	AGS68089.1	COG1960 Acyl-CoA dehydrogenases. (408 aa)
	AGS68199.1	3-ketoacyl-CoA thiolase/acetyl-CoA acetyltransferase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
	AGS68262.1	Hypothetical protein; COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon. (141 aa)
	AGS68263.1	Lipid-transfer protein; COG0183 Acetyl-CoA acetyltransferase. (396 aa)
	AGS68302.1	COG1960 Acyl-CoA dehydrogenases. (390 aa)
	AGS68574.1	COG1960 Acyl-CoA dehydrogenases. (404 aa)
	AGS68591.1	COG1960 Acyl-CoA dehydrogenases. (383 aa)
	AGS68614.1	Secreted hydrolase. (268 aa)
	AGS68630.1	Lipase; COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold. (280 aa)
	AGS68638.1	COG1960 Acyl-CoA dehydrogenases. (396 aa)
	AGS68909.1	Hypothetical protein. (285 aa)
	AGS68936.1	COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit. (283 aa)
	AGS68937.1	CoA-transferase subunit beta; COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit. (246 aa)
	AGS68938.1	enoyl-ACP reductase II; COG2070 Dioxygenases related to 2-nitropropane dioxygenase. (352 aa)
	AGS68939.1	COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (385 aa)
	AGS68942.1	COG1960 Acyl-CoA dehydrogenases. (379 aa)
	AGS68943.1	Oxidoreductase; COG1960 Acyl-CoA dehydrogenases. (318 aa)
	AGS69117.1	NAD dependent epimerase/dehydratase family protein; COG1090 Predicted nucleoside-diphosphate sugar epimerase. (298 aa)
	AGS69244.1	Lipid-transfer protein; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
	AGS69271.1	COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
	AGS69328.1	Esterase; COG1680 Beta-lactamase class C and other penicillin binding proteins. (385 aa)
	AGS69472.1	COG1960 Acyl-CoA dehydrogenases. (573 aa)
	AGS69745.1	COG1960 Acyl-CoA dehydrogenases. (385 aa)
	AGS69750.1	COG1960 Acyl-CoA dehydrogenases. (386 aa)
	AGS69986.1	COG1960 Acyl-CoA dehydrogenases. (385 aa)
	AGS70020.1	COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
	AGS70096.1	Esterase; COG1680 Beta-lactamase class C and other penicillin binding proteins. (388 aa)
	AGS70202.1	Lipid-transfer protein; COG0183 Acetyl-CoA acetyltransferase. (384 aa)
	AGS70203.1	Hypothetical protein; COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon. (135 aa)
	AGS70212.1	COG1960 Acyl-CoA dehydrogenases. (400 aa)
	AGS70213.1	Hypothetical protein; COG0183 Acetyl-CoA acetyltransferase. (390 aa)
	AGS70215.1	Hypothetical protein; COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon. (131 aa)
	AGS70224.1	COG1960 Acyl-CoA dehydrogenases. (382 aa)
	AGS70228.1	COG1960 Acyl-CoA dehydrogenases. (295 aa)
	AGS70229.1	Oxidoreductase; COG1960 Acyl-CoA dehydrogenases. (377 aa)
	AGS70256.1	COG1960 Acyl-CoA dehydrogenases. (386 aa)
	AGS70259.1	Hypothetical protein. (555 aa)
	AGS70265.1	Hypothetical protein. (227 aa)
	AGS70551.1	Lipid-transfer protein; COG0183 Acetyl-CoA acetyltransferase. (388 aa)
	AGS70552.1	Hypothetical protein; COG2030 Acyl dehydratase. (231 aa)
	AGS70553.1	Hypothetical protein; COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon. (327 aa)
	AGS70686.1	COG1960 Acyl-CoA dehydrogenases. (377 aa)
	AGS70722.1	COG1960 Acyl-CoA dehydrogenases. (608 aa)
	AGS70771.1	Hypothetical protein; COG1960 Acyl-CoA dehydrogenases. (376 aa)
	AGS71301.1	Cholesterol oxidase; COG2303 Choline dehydrogenase and related flavoproteins. (596 aa)
	AGS71318.1	Lipase; COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold. (283 aa)
	pckG	Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (607 aa)
	AGS71488.1	Hypothetical protein; COG0221 Inorganic pyrophosphatase. (599 aa)
	AGS71873.1	Acyltransferase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
	AGS72135.1	COG1960 Acyl-CoA dehydrogenases. (645 aa)
	AGS72375.1	COG1960 Acyl-CoA dehydrogenases. (377 aa)
	AGS72399.1	Isobutylamine N-hydroxylase; COG1960 Acyl-CoA dehydrogenases. (380 aa)
	AGS72459.1	Fatty acid oxidation complex alpha-subunit; COG1024 Enoyl-CoA hydratase/carnithine racemase. (709 aa)
	AGS72460.1	COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
	AGS72555.1	COG1960 Acyl-CoA dehydrogenases. (529 aa)
	AGS72565.1	Carboxyvinyl-carboxyphosphonate phosphorylmutase; COG2513 PEP phosphonomutase and related enzymes. (287 aa)
	AGS72620.1	Patatin; COG1752 Predicted esterase of the alpha-beta hydrolase superfamily. (281 aa)
	AGS72756.1	COG1960 Acyl-CoA dehydrogenases. (401 aa)
	AGS72779.1	Phenylacetic acid degradation NADH oxidoreductase PaaE; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. (372 aa)
	AGS72945.1	COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
	AGS72946.1	Fatty acid oxidative multifunctional enzyme; COG1024 Enoyl-CoA hydratase/carnithine racemase. (727 aa)
	AGS73012.1	Lipase; COG2267 Lysophospholipase. (265 aa)
	AGS73013.1	beta-ketoadipyl-CoA thiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
	AGS73147.1	COG1960 Acyl-CoA dehydrogenases. (398 aa)
	AGS73428.1	Platelet-activating factor acetylhydrolase; COG4188 Predicted dienelactone hydrolase. (414 aa)
	AGS73632.1	COG1960 Acyl-CoA dehydrogenases. (655 aa)
	AGS73662.1	COG1960 Acyl-CoA dehydrogenases. (409 aa)
	AGS73663.1	COG1960 Acyl-CoA dehydrogenases. (386 aa)
	AGS73762.1	COG1960 Acyl-CoA dehydrogenases. (402 aa)
	AGS73677.1	Lipase; COG4188 Predicted dienelactone hydrolase. (401 aa)
	AGS73761.1	COG1960 Acyl-CoA dehydrogenases. (343 aa)
	AGS73685.1	Hypothetical protein; COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold. (509 aa)
	AGS66932.1	COG1960 Acyl-CoA dehydrogenases. (402 aa)
	AGS66933.1	COG1960 Acyl-CoA dehydrogenases. (343 aa)
	AGS67009.1	Hypothetical protein; COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold. (509 aa)
	AGS67017.1	Lipase; COG4188 Predicted dienelactone hydrolase. (401 aa)
	AGS67031.1	COG1960 Acyl-CoA dehydrogenases. (386 aa)
	AGS67032.1	COG1960 Acyl-CoA dehydrogenases. (409 aa)
	AGS67063.1	COG1960 Acyl-CoA dehydrogenases. (655 aa)
	AGS67267.1	Platelet-activating factor acetylhydrolase; COG4188 Predicted dienelactone hydrolase. (446 aa)
	AGS67333.1	Hypothetical protein. (175 aa)

Your Current Organism:

Streptomyces collinus

NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGS66932.1	AGS66933.1	B446_00460	B446_00465	COG1960 Acyl-CoA dehydrogenases.	COG1960 Acyl-CoA dehydrogenases.	0.967
AGS66932.1	AGS67031.1	B446_00460	B446_00965	COG1960 Acyl-CoA dehydrogenases.	COG1960 Acyl-CoA dehydrogenases.	0.902
AGS66932.1	AGS67032.1	B446_00460	B446_00970	COG1960 Acyl-CoA dehydrogenases.	COG1960 Acyl-CoA dehydrogenases.	0.646
AGS66932.1	AGS67464.1	B446_00460	B446_03160	COG1960 Acyl-CoA dehydrogenases.	COG1960 Acyl-CoA dehydrogenases.	0.920
AGS66932.1	AGS67465.1	B446_00460	B446_03165	COG1960 Acyl-CoA dehydrogenases.	COG1960 Acyl-CoA dehydrogenases.	0.922
AGS66932.1	AGS67769.1	B446_00460	B446_04705	COG1960 Acyl-CoA dehydrogenases.	COG0183 Acetyl-CoA acetyltransferase.	0.757
AGS66932.1	AGS67770.1	B446_00460	B446_04710	COG1960 Acyl-CoA dehydrogenases.	Lipid-transfer protein; COG0183 Acetyl-CoA acetyltransferase.	0.433
AGS66932.1	AGS67884.1	B446_00460	B446_05290	COG1960 Acyl-CoA dehydrogenases.	COG1960 Acyl-CoA dehydrogenases.	0.915
AGS66932.1	AGS68199.1	B446_00460	B446_06875	COG1960 Acyl-CoA dehydrogenases.	3-ketoacyl-CoA thiolase/acetyl-CoA acetyltransferase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.757
AGS66932.1	AGS68574.1	B446_00460	B446_08750	COG1960 Acyl-CoA dehydrogenases.	COG1960 Acyl-CoA dehydrogenases.	0.911
AGS66932.1	AGS68638.1	B446_00460	B446_09070	COG1960 Acyl-CoA dehydrogenases.	COG1960 Acyl-CoA dehydrogenases.	0.915
AGS66932.1	AGS68939.1	B446_00460	B446_10585	COG1960 Acyl-CoA dehydrogenases.	COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.757
AGS66932.1	AGS69244.1	B446_00460	B446_12110	COG1960 Acyl-CoA dehydrogenases.	Lipid-transfer protein; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.757
AGS66932.1	AGS69271.1	B446_00460	B446_12245	COG1960 Acyl-CoA dehydrogenases.	COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.757
AGS66932.1	AGS69745.1	B446_00460	B446_14635	COG1960 Acyl-CoA dehydrogenases.	COG1960 Acyl-CoA dehydrogenases.	0.920
AGS66932.1	AGS69750.1	B446_00460	B446_14660	COG1960 Acyl-CoA dehydrogenases.	COG1960 Acyl-CoA dehydrogenases.	0.932
AGS66932.1	AGS70020.1	B446_00460	B446_16010	COG1960 Acyl-CoA dehydrogenases.	COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.757
AGS66932.1	AGS70551.1	B446_00460	B446_18685	COG1960 Acyl-CoA dehydrogenases.	Lipid-transfer protein; COG0183 Acetyl-CoA acetyltransferase.	0.426
AGS66932.1	AGS70552.1	B446_00460	B446_18690	COG1960 Acyl-CoA dehydrogenases.	Hypothetical protein; COG2030 Acyl dehydratase.	0.418
AGS66932.1	AGS71873.1	B446_00460	B446_25310	COG1960 Acyl-CoA dehydrogenases.	Acyltransferase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.757