STRINGSTRING
fbiC fbiC AGS70081.1 AGS70081.1 ppc ppc eno eno AGS70016.1 AGS70016.1 hutU hutU purK purK AGS69902.1 AGS69902.1 AGS69896.1 AGS69896.1 AGS69819.1 AGS69819.1 AGS69753.1 AGS69753.1 AGS69727.1 AGS69727.1 AGS69708.1 AGS69708.1 AGS69601.1 AGS69601.1 AGS69575.1 AGS69575.1 AGS69516.1 AGS69516.1 AGS69511.1 AGS69511.1 AGS69447.1 AGS69447.1 AGS69446.1 AGS69446.1 AGS69405.1 AGS69405.1 AGS69366.1 AGS69366.1 AGS69294.1 AGS69294.1 AGS69237.1 AGS69237.1 AGS69229.1 AGS69229.1 AGS69017.1 AGS69017.1 hisB hisB hisH hisH hisF hisF AGS68967.1 AGS68967.1 trpE trpE trpC trpC trpB trpB trpA trpA AGS68954.1 AGS68954.1 AGS68937.1 AGS68937.1 AGS68936.1 AGS68936.1 AGS68926.1 AGS68926.1 psuG psuG aroQ aroQ dapA dapA AGS68785.1 AGS68785.1 AGS68778.1 AGS68778.1 AGS68777.1 AGS68777.1 ectC ectC AGS68755.1 AGS68755.1 cobD cobD AGS68722.1 AGS68722.1 AGS68720.1 AGS68720.1 AGS68719.1 AGS68719.1 moaA moaA AGS68588.1 AGS68588.1 AGS68576.1 AGS68576.1 AGS68489.1 AGS68489.1 AGS68463.1 AGS68463.1 argH argH pdxS pdxS pdxT pdxT mltG-2 mltG-2 aroC aroC aroB aroB pyrF pyrF AGS68350.1 AGS68350.1 ribBA ribBA AGS68278.1 AGS68278.1 AGS68262.1 AGS68262.1 AGS68179.1 AGS68179.1 AGS68138.1 AGS68138.1 mltG mltG AGS67975.1 AGS67975.1 AGS67964.1 AGS67964.1 AGS67949.1 AGS67949.1 AGS67944.1 AGS67944.1 AGS67937.1 AGS67937.1 AGS67915.1 AGS67915.1 AGS67907.1 AGS67907.1 AGS67862.1 AGS67862.1 aspA aspA AGS67814.1 AGS67814.1 AGS67771.1 AGS67771.1 AGS67741.1 AGS67741.1 AGS67713.1 AGS67713.1 AGS67711.1 AGS67711.1 AGS67698.1 AGS67698.1 AGS67609.1 AGS67609.1 AGS67367.1 AGS67367.1 AGS67350.1 AGS67350.1 AGS67312.1 AGS67312.1 AGS67248.1 AGS67248.1 kirD kirD AGS67146.1 AGS67146.1 AGS66930.1 AGS66930.1 AGS66927.1 AGS66927.1 AGS66906.1 AGS66906.1 AGS73788.1 AGS73788.1 AGS73767.1 AGS73767.1 AGS73764.1 AGS73764.1 AGS73548.1 AGS73548.1 kirD-2 kirD-2 AGS73446.1 AGS73446.1 AGS73309.1 AGS73309.1 panD panD AGS73100.1 AGS73100.1 AGS73052.1 AGS73052.1 AGS73047.1 AGS73047.1 AGS72958.1 AGS72958.1 AGS72932.1 AGS72932.1 AGS72920.1 AGS72920.1 AGS72918.1 AGS72918.1 AGS72866.1 AGS72866.1 AGS72828.1 AGS72828.1 phhB phhB AGS72763.1 AGS72763.1 AGS72758.1 AGS72758.1 AGS72757.1 AGS72757.1 psd psd AGS72746.1 AGS72746.1 AGS72745.1 AGS72745.1 AGS72639.1 AGS72639.1 AGS72631.1 AGS72631.1 AGS72565.1 AGS72565.1 AGS72541.1 AGS72541.1 AGS72537.1 AGS72537.1 AGS72536.1 AGS72536.1 AGS72508.1 AGS72508.1 AGS72481.1 AGS72481.1 hemE hemE AGS72442.1 AGS72442.1 AGS72424.1 AGS72424.1 AGS72413.1 AGS72413.1 AGS72371.1 AGS72371.1 AGS72322.1 AGS72322.1 AGS72319.1 AGS72319.1 hemH hemH AGS72285.1 AGS72285.1 AGS72196.1 AGS72196.1 dapA-2 dapA-2 AGS72107.1 AGS72107.1 mutM mutM leuD leuD leuC leuC AGS71973.1 AGS71973.1 AGS71934.1 AGS71934.1 AGS71872.1 AGS71872.1 AGS71831.1 AGS71831.1 lysA lysA kgd kgd AGS71768.1 AGS71768.1 AGS71734.1 AGS71734.1 AGS71733.1 AGS71733.1 AGS71647.1 AGS71647.1 AGS71553.1 AGS71553.1 AGS71552.1 AGS71552.1 AGS71534.1 AGS71534.1 fumC fumC AGS71482.1 AGS71482.1 pckG pckG AGS71458.1 AGS71458.1 AGS71454.1 AGS71454.1 hutH hutH AGS71436.1 AGS71436.1 AGS71426.1 AGS71426.1 AGS71422.1 AGS71422.1 AGS71371.1 AGS71371.1 AGS71323.1 AGS71323.1 AGS71305.1 AGS71305.1 nnrD nnrD AGS71194.1 AGS71194.1 mqnA mqnA AGS71084.1 AGS71084.1 AGS71082.1 AGS71082.1 AGS71024.1 AGS71024.1 AGS71022.1 AGS71022.1 ilvD ilvD disA disA AGS70968.1 AGS70968.1 AGS70955.1 AGS70955.1 AGS70940.1 AGS70940.1 AGS70898.1 AGS70898.1 nth nth AGS70815.1 AGS70815.1 AGS70689.1 AGS70689.1 AGS70605.1 AGS70605.1 thiC thiC AGS70574.1 AGS70574.1 AGS70553.1 AGS70553.1 AGS70552.1 AGS70552.1 AGS70512.1 AGS70512.1 AGS70508.1 AGS70508.1 ispF ispF AGS70340.1 AGS70340.1 AGS70315.1 AGS70315.1 murQ murQ mqnD mqnD AGS70259.1 AGS70259.1 AGS70230.1 AGS70230.1 AGS70219.1 AGS70219.1 AGS70215.1 AGS70215.1 AGS70207.1 AGS70207.1 AGS70204.1 AGS70204.1 AGS70203.1 AGS70203.1 AGS70198.1 AGS70198.1 moaC moaC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fbiCFO synthase; COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. (846 aa)
AGS70081.1Hypothetical protein; COG0666 FOG: Ankyrin repeat. (438 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (910 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (438 aa)
AGS70016.1COG2986 Histidine ammonia-lyase. (497 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (554 aa)
purKPhosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (372 aa)
AGS69902.1Bifunctional uroporphyrinogen-III synthetase/response regulator domain protein; COG1587 Uroporphyrinogen-III synthase. (387 aa)
AGS69896.1Malate oxidoreductase; COG0281 Malic enzyme. (471 aa)
AGS69819.12-hydroxyhepta-2,4-diene-1,7-dioate isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (285 aa)
AGS69753.1Decarboxylase; COG0076 Glutamate decarboxylase and related PLP-dependent proteins. (480 aa)
AGS69727.1Hypothetical protein. (383 aa)
AGS69708.1Hypothetical protein. (315 aa)
AGS69601.1Endonuclease VIII and DNA N-glycosylase with an AP lyase activity; COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (269 aa)
AGS69575.1Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. (213 aa)
AGS69516.1NDP-hexose 23-dehydratase. (497 aa)
AGS69511.1COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (330 aa)
AGS69447.15-dehydro-4-deoxyglucarate dehydratase; COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. (298 aa)
AGS69446.1Glucarate dehydratase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (429 aa)
AGS69405.1Lysine biosynthesis protein; COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. (308 aa)
AGS69366.1Hypothetical protein. (292 aa)
AGS69294.1ATP/GTP-binding protein; COG2301 Citrate lyase beta subunit. (388 aa)
AGS69237.1Dehydrogenase; COG2030 Acyl dehydratase. (291 aa)
AGS69229.12-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. (230 aa)
AGS69017.1COG0288 Carbonic anhydrase. (193 aa)
hisBCOG0131 Imidazoleglycerol-phosphate dehydratase. (200 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (207 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa)
AGS68967.1Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases. (132 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (498 aa)
trpCCOG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (269 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (427 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (272 aa)
AGS68954.1COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. (270 aa)
AGS68937.1CoA-transferase subunit beta; COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit. (246 aa)
AGS68936.1COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit. (283 aa)
AGS68926.1Amino acid decarboxylase; COG0076 Glutamate decarboxylase and related PLP-dependent proteins. (452 aa)
psuGHypothetical protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (302 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (157 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (298 aa)
AGS68785.15-dehydro-4-deoxyglucarate dehydratase; COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. (313 aa)
AGS68778.1COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. (303 aa)
AGS68777.1COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (580 aa)
ectCL-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (134 aa)
AGS68755.1Metal binding protein. (303 aa)
cobDCobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (314 aa)
AGS68722.1Hypothetical protein; COG4689 Acetoacetate decarboxylase. (265 aa)
AGS68720.1Amidohydrolase; COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold. (428 aa)
AGS68719.1Amidohydrolase; COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold. (408 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa)
AGS68588.1Hypothetical protein; COG2030 Acyl dehydratase. (153 aa)
AGS68576.1Orn/DAP/Arg decarboxylase 2; COG0019 Diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (450 aa)
AGS68489.1Hypothetical protein; COG3616 Predicted amino acid aldolase or racemase. (400 aa)
AGS68463.1COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. (148 aa)
argHCOG0165 Argininosuccinate lyase. (477 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (301 aa)
pdxTGlutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (201 aa)
mltG-2Integral membrane protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (559 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (394 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (363 aa)
pyrFCOG0284 Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (281 aa)
AGS68350.1Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (400 aa)
ribBABifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (437 aa)
AGS68278.1Hypothetical protein; Belongs to the D-glutamate cyclase family. (279 aa)
AGS68262.1Hypothetical protein; COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon. (141 aa)
AGS68179.1Siderophore binding protein; COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily. (175 aa)
AGS68138.1COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (480 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (309 aa)
AGS67975.1Hypothetical protein. (140 aa)
AGS67964.1Hypothetical protein. (306 aa)
AGS67949.1Hydroxylase; COG3324 Predicted enzyme related to lactoylglutathione lyase. (254 aa)
AGS67944.1Aldolase; COG2008 Threonine aldolase. (356 aa)
AGS67937.1Hypothetical protein; COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. (432 aa)
AGS67915.1COG0191 Fructose/tagatose bisphosphate aldolase. (292 aa)
AGS67907.1Cysteine synthase/cystathionine beta-synthase family protein; COG0031 Cysteine synthase. (374 aa)
AGS67862.1Hypothetical protein; COG3324 Predicted enzyme related to lactoylglutathione lyase. (116 aa)
aspACOG1027 Aspartate ammonia-lyase. (469 aa)
AGS67814.1Hypothetical protein. (232 aa)
AGS67771.1Hypothetical protein; COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon. (313 aa)
AGS67741.1COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. (458 aa)
AGS67713.1Hypothetical protein. (350 aa)
AGS67711.1Hydroxylase; COG3324 Predicted enzyme related to lactoylglutathione lyase. (313 aa)
AGS67698.1COG1171 Threonine dehydratase. (322 aa)
AGS67609.1Hypothetical protein; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. (333 aa)
AGS67367.1Hypothetical protein; COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold. (299 aa)
AGS67350.1COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. (108 aa)
AGS67312.1Amino acid decarboxylase; COG1982 Arginine/lysine/ornithine decarboxylases. (492 aa)
AGS67248.1Hypothetical protein. (471 aa)
kirDL-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (146 aa)
AGS67146.1COG0165 Argininosuccinate lyase. (539 aa)
AGS66930.1Orn/DAP/Arg decarboxylase 2; COG0019 Diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (434 aa)
AGS66927.1Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (473 aa)
AGS66906.1LuxR family transcriptional regulator; COG3899 Predicted ATPase. (863 aa)
AGS73788.1LuxR family transcriptional regulator; COG3899 Predicted ATPase. (863 aa)
AGS73767.1COG1350 Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB). (473 aa)
AGS73764.1Orn/DAP/Arg decarboxylase 2; COG0019 Diaminopimelate decarboxylase. (434 aa)
AGS73548.1COG0165 Argininosuccinate lyase. (539 aa)
kirD-2COG0853 Aspartate 1-decarboxylase. (146 aa)
AGS73446.1Hypothetical protein. (471 aa)
AGS73309.1Hypothetical protein; COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase. (177 aa)
panDAspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (140 aa)
AGS73100.1COG2008 Threonine aldolase. (399 aa)
AGS73052.1Regulatory protein; COG2771 DNA-binding HTH domain-containing proteins. (594 aa)
AGS73047.1COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. (302 aa)
AGS72958.1COG1024 Enoyl-CoA hydratase/carnithine racemase. (247 aa)
AGS72932.1Hydroxylase; COG3324 Predicted enzyme related to lactoylglutathione lyase. (264 aa)
AGS72920.13-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. (452 aa)
AGS72918.1Regulatory protein; COG3899 Predicted ATPase. (894 aa)
AGS72866.1Hypothetical protein; COG0720 6-pyruvoyl-tetrahydropterin synthase. (132 aa)
AGS72828.1Hypothetical protein. (213 aa)
phhBCOG2154 Pterin-4a-carbinolamine dehydratase. (101 aa)
AGS72763.1Adenylosuccinate lyase; COG1413 FOG: HEAT repeat. (190 aa)
AGS72758.1COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. (320 aa)
AGS72757.1Hypothetical protein; COG2030 Acyl dehydratase. (174 aa)
psdPhosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (218 aa)
AGS72746.1COG2124 Cytochrome P450. (464 aa)
AGS72745.1Pentalenene synthase. (336 aa)
AGS72639.1OHCU decarboxylase; COG3195 Uncharacterized protein conserved in bacteria. (170 aa)
AGS72631.1COG3960 Glyoxylate carboligase; Belongs to the TPP enzyme family. (595 aa)
AGS72565.1Carboxyvinyl-carboxyphosphonate phosphorylmutase; COG2513 PEP phosphonomutase and related enzymes. (287 aa)
AGS72541.1Hypothetical protein. (246 aa)
AGS72537.1COG2124 Cytochrome P450. (445 aa)
AGS72536.1COG2124 Cytochrome P450. (452 aa)
AGS72508.1Germacradienol synthase. (720 aa)
AGS72481.1Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (192 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (355 aa)
AGS72442.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
AGS72424.1COG0019 Diaminopimelate decarboxylase. (398 aa)
AGS72413.1COG2079 Uncharacterized protein involved in propionate catabolism. (522 aa)
AGS72371.1COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (275 aa)
AGS72322.1Phosphoenolpyruvate phosphomutase; COG2513 PEP phosphonomutase and related enzymes. (289 aa)
AGS72319.1NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (280 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (375 aa)
AGS72285.1Hydroxylase; COG3324 Predicted enzyme related to lactoylglutathione lyase. (263 aa)
AGS72196.1DNA glycosylase; COG0266 Formamidopyrimidine-DNA glycosylase. (284 aa)
dapA-2Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (299 aa)
AGS72107.1Hypothetical protein; COG3607 Predicted lactoylglutathione lyase. (135 aa)
mutMFormamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (286 aa)
leuDIsopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa)
leuCIsopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (474 aa)
AGS71973.1LuxR family transcriptional regulator; COG3899 Predicted ATPase. (1012 aa)
AGS71934.1COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa)
AGS71872.1methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases. (146 aa)
AGS71831.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (352 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (463 aa)
kgdAlpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. (1268 aa)
AGS71768.1Malate oxidoreductase; COG0281 Malic enzyme. (406 aa)
AGS71734.1COG2124 Cytochrome P450. (456 aa)
AGS71733.1Terpene cyclase. (337 aa)
AGS71647.1COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (267 aa)
AGS71553.1Glutamine amidotransferase of anthranilate synthase; COG0512 Anthranilate/para-aminobenzoate synthases component II. (195 aa)
AGS71552.1COG0147 Anthranilate/para-aminobenzoate synthases component I. (504 aa)
AGS71534.1Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (554 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa)
AGS71482.1D-amino acid deaminase; COG3616 Predicted amino acid aldolase or racemase. (425 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (607 aa)
AGS71458.1COG1171 Threonine dehydratase. (409 aa)
AGS71454.1COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (384 aa)
hutHCOG2986 Histidine ammonia-lyase. (514 aa)
AGS71436.1COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). (374 aa)
AGS71426.1Hypothetical protein. (145 aa)
AGS71422.1Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (319 aa)
AGS71371.1OHCU decarboxylase. (190 aa)
AGS71323.1Hypothetical protein. (857 aa)
AGS71305.1Hypothetical protein; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases. (264 aa)
nnrDHypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (464 aa)
AGS71194.1Hypothetical protein; COG2030 Acyl dehydratase; Belongs to the UPF0336 family. (150 aa)
mqnAHypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (282 aa)
AGS71084.1Octaprenyl carboxylase; COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase. (198 aa)
AGS71082.1Decarboxylase; COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family. (485 aa)
AGS71024.1COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (310 aa)
AGS71022.1uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; COG0007 Uroporphyrinogen-III methylase. (569 aa)
ilvDCOG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (617 aa)
disADNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis. (352 aa)
AGS70968.1COG2008 Threonine aldolase. (402 aa)
AGS70955.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (119 aa)
AGS70940.1COG0076 Glutamate decarboxylase and related PLP-dependent proteins; Belongs to the group II decarboxylase family. (468 aa)
AGS70898.1Integral membrane transport protein; COG0659 Sulfate permease and related transporters (MFS superfamily). (816 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (330 aa)
AGS70815.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
AGS70689.1Hypothetical protein. (448 aa)
AGS70605.1COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (382 aa)
thiCPhosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (594 aa)
AGS70574.1COG0077 Prephenate dehydratase. (294 aa)
AGS70553.1Hypothetical protein; COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon. (327 aa)
AGS70552.1Hypothetical protein; COG2030 Acyl dehydratase. (231 aa)
AGS70512.1Hypothetical protein; COG0177 Predicted EndoIII-related endonuclease. (206 aa)
AGS70508.1Hypothetical protein; COG4195 Phage-related replication protein. (217 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (203 aa)
AGS70340.1PKSA cyclase II. (107 aa)
AGS70315.1COG0498 Threonine synthase. (392 aa)
murQN-acetylmuramic acid-6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (307 aa)
mqnDHypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (282 aa)
AGS70259.1Hypothetical protein. (555 aa)
AGS70230.1Amidohydrolase; COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold. (397 aa)
AGS70219.1COG1024 Enoyl-CoA hydratase/carnithine racemase. (264 aa)
AGS70215.1Hypothetical protein; COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon. (131 aa)
AGS70207.1Hydrolase; COG3324 Predicted enzyme related to lactoylglutathione lyase. (233 aa)
AGS70204.1COG1024 Enoyl-CoA hydratase/carnithine racemase. (255 aa)
AGS70203.1Hypothetical protein; COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon. (135 aa)
AGS70198.1Amidohydrolase; COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold. (414 aa)
moaCMolybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (170 aa)
Your Current Organism:
Streptomyces collinus
NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365
Server load: low (24%) [HD]