STRINGSTRING
AGS66848.1 AGS66848.1 AGS66857.1 AGS66857.1 AGS66858.1 AGS66858.1 AGS66981.1 AGS66981.1 AGS67052.1 AGS67052.1 AGS67053.1 AGS67053.1 kirM kirM AGS67220.1 AGS67220.1 AGS67381.1 AGS67381.1 AGS67683.1 AGS67683.1 AGS67714.1 AGS67714.1 AGS67785.1 AGS67785.1 AGS67788.1 AGS67788.1 AGS67822.1 AGS67822.1 AGS67843.1 AGS67843.1 AGS67874.1 AGS67874.1 rlmG rlmG AGS68008.1 AGS68008.1 AGS68129.1 AGS68129.1 AGS68345.1 AGS68345.1 AGS68422.1 AGS68422.1 AGS68423.1 AGS68423.1 AGS68425.1 AGS68425.1 AGS68480.1 AGS68480.1 AGS68529.1 AGS68529.1 AGS68535.1 AGS68535.1 AGS68605.1 AGS68605.1 AGS68626.1 AGS68626.1 AGS68670.1 AGS68670.1 AGS68749.1 AGS68749.1 AGS68751.1 AGS68751.1 AGS68752.1 AGS68752.1 AGS68753.1 AGS68753.1 AGS68875.1 AGS68875.1 AGS68879.1 AGS68879.1 AGS68885.1 AGS68885.1 AGS68904.1 AGS68904.1 rsmH rsmH AGS69022.1 AGS69022.1 AGS69214.1 AGS69214.1 AGS69246.1 AGS69246.1 AGS69253.1 AGS69253.1 AGS69273.1 AGS69273.1 AGS69456.1 AGS69456.1 AGS69579.1 AGS69579.1 AGS69658.1 AGS69658.1 AGS70041.1 AGS70041.1 tam tam ksgA ksgA rsmI rsmI AGS70158.1 AGS70158.1 AGS70352.1 AGS70352.1 trmB trmB gidB gidB AGS70690.1 AGS70690.1 AGS70915.1 AGS70915.1 AGS70964.1 AGS70964.1 AGS71002.1 AGS71002.1 AGS71022.1 AGS71022.1 AGS71097.1 AGS71097.1 ubiE ubiE AGS71276.1 AGS71276.1 AGS71515.1 AGS71515.1 AGS71532.1 AGS71532.1 AGS71612.1 AGS71612.1 AGS71649.1 AGS71649.1 AGS71764.1 AGS71764.1 prmC prmC AGS71962.1 AGS71962.1 AGS72040.1 AGS72040.1 AGS72066.1 AGS72066.1 trmD trmD rlmN rlmN thyX thyX AGS72309.1 AGS72309.1 AGS72320.1 AGS72320.1 AGS72339.1 AGS72339.1 AGS72356.1 AGS72356.1 mmuM mmuM AGS72584.1 AGS72584.1 AGS72733.1 AGS72733.1 AGS72734.1 AGS72734.1 AGS72769.1 AGS72769.1 AGS72797.1 AGS72797.1 AGS72817.1 AGS72817.1 AGS72822.1 AGS72822.1 AGS72826.1 AGS72826.1 AGS73008.1 AGS73008.1 AGS73017.1 AGS73017.1 AGS73189.1 AGS73189.1 egtD egtD AGS73301.1 AGS73301.1 AGS73321.1 AGS73321.1 AGS73328.1 AGS73328.1 AGS73353.1 AGS73353.1 AGS73474.1 AGS73474.1 kirM-2 kirM-2 AGS73642.1 AGS73642.1 AGS73643.1 AGS73643.1 AGS73713.1 AGS73713.1 AGS73836.1 AGS73836.1 AGS73837.1 AGS73837.1 AGS73846.1 AGS73846.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGS66848.1COG4889 Predicted helicase. (859 aa)
AGS66857.1Hypothetical protein. (373 aa)
AGS66858.1Gp37Gp68 family protein; COG4422 Bacteriophage protein gp37. (251 aa)
AGS66981.1Methyltransferase; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. (287 aa)
AGS67052.1Hypothetical protein. (212 aa)
AGS67053.1Hypothetical protein. (253 aa)
kirMCOG0500 SAM-dependent methyltransferases. (312 aa)
AGS67220.1Radical SAM domain containing enzyme; COG1032 Fe-S oxidoreductase. (421 aa)
AGS67381.1Methyltransferase; COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis. (244 aa)
AGS67683.1Hypothetical protein. (112 aa)
AGS67714.1Methyltransferase; COG0500 SAM-dependent methyltransferases. (292 aa)
AGS67785.1Radical SAM; COG1032 Fe-S oxidoreductase. (640 aa)
AGS67788.1Radical SAM protein; COG1032 Fe-S oxidoreductase. (647 aa)
AGS67822.1Methyltransferase; COG2890 Methylase of polypeptide chain release factors. (278 aa)
AGS67843.1Methyltransferase; COG0500 SAM-dependent methyltransferases. (259 aa)
AGS67874.1Ubiquinone/menaquinone biosynthesis methyltransferase. (100 aa)
rlmGRibosomal RNA small subunit methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (378 aa)
AGS68008.1Methyltransferase; COG0500 SAM-dependent methyltransferases. (202 aa)
AGS68129.1Hypothetical protein; COG0500 SAM-dependent methyltransferases. (230 aa)
AGS68345.1RNA-binding Sun protein; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (475 aa)
AGS68422.1COG0566 rRNA methylases. (272 aa)
AGS68423.1uroporphyrin-III methyltransferase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); Belongs to the precorrin methyltransferase family. (409 aa)
AGS68425.1precorrin-6Y C5,15-methyltransferase; COG2241 Precorrin-6B methylase 1. (408 aa)
AGS68480.1COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (285 aa)
AGS68529.1Hypothetical protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. (299 aa)
AGS68535.15-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1156 aa)
AGS68605.1Hypothetical protein. (384 aa)
AGS68626.1Hypothetical protein; COG0500 SAM-dependent methyltransferases. (206 aa)
AGS68670.1COG1189 Predicted rRNA methylase. (271 aa)
AGS68749.1COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. (247 aa)
AGS68751.1COG2875 Precorrin-4 methylase. (272 aa)
AGS68752.1precorrin-6Y C5,15-methyltransferase; COG2241 Precorrin-6B methylase 1. (413 aa)
AGS68753.1Precorrin methylase; COG2073 Cobalamin biosynthesis protein CbiG. (566 aa)
AGS68875.1methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (184 aa)
AGS68879.1Methyltransferase; COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis. (264 aa)
AGS68885.1Hypothetical protein. (114 aa)
AGS68904.1COG0500 SAM-dependent methyltransferases. (220 aa)
rsmH16S rRNA m(4)C1402 methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (318 aa)
AGS69022.1Methyltransferase; COG0500 SAM-dependent methyltransferases. (256 aa)
AGS69214.1Hypothetical protein; COG5459 Predicted rRNA methylase. (331 aa)
AGS69246.1Hypothetical protein. (216 aa)
AGS69253.1Methyltransferase; COG0500 SAM-dependent methyltransferases. (250 aa)
AGS69273.1COG4122 Predicted O-methyltransferase. (223 aa)
AGS69456.116S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (248 aa)
AGS69579.1Hypothetical protein; COG1032 Fe-S oxidoreductase. (653 aa)
AGS69658.1O-methyltransferase; COG2518 Protein-L-isoaspartate carboxylmethyltransferase. (325 aa)
AGS70041.1Type II restriction-modification system DNA adenine-specific methylase; COG0286 Type I restriction-modification system methyltransferase subunit. (765 aa)
tamTrans-aconitate 2-methyltransferase; Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate. (272 aa)
ksgA16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (289 aa)
rsmITetrapyrrole methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (283 aa)
AGS70158.1Hypothetical protein; COG0500 SAM-dependent methyltransferases. (233 aa)
AGS70352.1COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (313 aa)
trmBtRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (280 aa)
gidB16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (238 aa)
AGS70690.1COG0566 rRNA methylases. (252 aa)
AGS70915.1rRNA or tRNA methyltransferase; COG2890 Methylase of polypeptide chain release factors; Belongs to the methyltransferase superfamily. (506 aa)
AGS70964.1Hypothetical protein. (365 aa)
AGS71002.1Hypothetical protein; COG0500 SAM-dependent methyltransferases. (259 aa)
AGS71022.1uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; COG0007 Uroporphyrinogen-III methylase. (569 aa)
AGS71097.1Methyltransferase; COG0500 SAM-dependent methyltransferases. (244 aa)
ubiEUbiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (231 aa)
AGS71276.1Hypothetical protein; COG0500 SAM-dependent methyltransferases. (419 aa)
AGS71515.1Hypothetical protein; COG0500 SAM-dependent methyltransferases. (261 aa)
AGS71532.1Methyltransferase type 11; COG0500 SAM-dependent methyltransferases. (221 aa)
AGS71612.1Methyltransferase; COG0500 SAM-dependent methyltransferases. (247 aa)
AGS71649.1COG4122 Predicted O-methyltransferase. (174 aa)
AGS71764.1Methyltransferase; COG0500 SAM-dependent methyltransferases. (252 aa)
prmCN5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (293 aa)
AGS71962.1Hypothetical protein. (333 aa)
AGS72040.1DNA methylase; COG0742 N6-adenine-specific methylase. (195 aa)
AGS72066.1Hypothetical protein; COG0500 SAM-dependent methyltransferases. (267 aa)
trmDtRNA (guanine37-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (277 aa)
rlmNRibosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (368 aa)
thyXFAD-dependent thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (242 aa)
AGS72309.1COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (442 aa)
AGS72320.1Putative O-methyltransferase. (224 aa)
AGS72339.1Putative methyltransferase; COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis. (221 aa)
AGS72356.1Radical SAM; COG1032 Fe-S oxidoreductase. (714 aa)
mmuMCOG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent). (311 aa)
AGS72584.1ADA-like regulatory protein; COG2169 Adenosine deaminase. (472 aa)
AGS72733.1ADA-like regulatory protein; COG2169 Adenosine deaminase. (499 aa)
AGS72734.1methylated-DNA--protein-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (163 aa)
AGS72769.1Hypothetical protein; COG0500 SAM-dependent methyltransferases. (244 aa)
AGS72797.1Hypothetical protein; COG0500 SAM-dependent methyltransferases. (278 aa)
AGS72817.1Hypothetical protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component. (270 aa)
AGS72822.1Hypothetical protein; COG0500 SAM-dependent methyltransferases. (248 aa)
AGS72826.1Hypothetical protein; COG0500 SAM-dependent methyltransferases. (317 aa)
AGS73008.1Hypothetical protein. (269 aa)
AGS73017.1Precorrin 6A synthase; COG2243 Precorrin-2 methylase. (259 aa)
AGS73189.1Hypothetical protein; COG0500 SAM-dependent methyltransferases. (270 aa)
egtDHypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. (320 aa)
AGS73301.1Hypothetical protein. (101 aa)
AGS73321.1methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (190 aa)
AGS73328.1Methyltransferase; COG2890 Methylase of polypeptide chain release factors. (217 aa)
AGS73353.1Type 11 methyltransferase. (267 aa)
AGS73474.1Radical SAM domain containing enzyme; COG1032 Fe-S oxidoreductase. (421 aa)
kirM-2COG0500 SAM-dependent methyltransferases. (312 aa)
AGS73642.1Hypothetical protein. (253 aa)
AGS73643.1Hypothetical protein. (212 aa)
AGS73713.1COG3315 O-Methyltransferase involved in polyketide biosynthesis. (287 aa)
AGS73836.1Gp37Gp68 family protein; COG4422 Bacteriophage protein gp37. (251 aa)
AGS73837.1Hypothetical protein. (373 aa)
AGS73846.1COG4889 Predicted helicase. (859 aa)
Your Current Organism:
Streptomyces collinus
NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365
Server load: medium (46%) [HD]