Your Input: | |
| | AGS66977.1 | Hypothetical protein. (365 aa) |
| | AGS67113.1 | COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family. (143 aa) |
| | AGS67250.1 | COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family. (143 aa) |
| | AGS67293.1 | COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (118 aa) |
| | htpG | Heat shock protein 90; Molecular chaperone. Has ATPase activity. (650 aa) |
| | msrA | Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (156 aa) |
| | AGS67635.1 | Hypothetical protein; COG1793 ATP-dependent DNA ligase. (203 aa) |
| | AGS67638.1 | Bacterioferritin comigratory protein; COG1225 Peroxiredoxin. (155 aa) |
| | AGS67644.1 | COG1793 ATP-dependent DNA ligase. (327 aa) |
| | AGS67686.1 | COG3145 Alkylated DNA repair protein. (209 aa) |
| | AGS67913.1 | COG3145 Alkylated DNA repair protein. (216 aa) |
| | ung | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (225 aa) |
| | AGS67997.1 | Integral membrane protein; COG1988 Predicted membrane-bound metal-dependent hydrolases. (264 aa) |
| | AGS67998.1 | COG4581 Superfamily II RNA helicase. (837 aa) |
| | ligB | ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (512 aa) |
| | AGS68139.1 | COG3663 G:T/U mismatch-specific DNA glycosylase. (176 aa) |
| | ung-2 | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (227 aa) |
| | AGS68217.1 | Hypothetical protein. (156 aa) |
| | AGS68221.1 | Hypothetical protein; COG3467 Predicted flavin-nucleotide-binding protein. (231 aa) |
| | dinB | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (455 aa) |
| | AGS68332.1 | Hydrolase; COG0637 Predicted phosphatase/phosphohexomutase. (491 aa) |
| | ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (355 aa) |
| | ruvA | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (201 aa) |
| | ruvC | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (179 aa) |
| | AGS68469.1 | Hypothetical protein. (65 aa) |
| | AGS68501.1 | COG2375 Siderophore-interacting protein. (282 aa) |
| | AGS68543.1 | Hypothetical protein. (265 aa) |
| | AGS68550.1 | Hypothetical protein; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. (764 aa) |
| | AGS68582.1 | Hypothetical protein. (434 aa) |
| | AGS68590.1 | COG4298 Uncharacterized protein conserved in bacteria. (107 aa) |
| | AGS68633.1 | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. (336 aa) |
| | AGS68634.1 | COG0587 DNA polymerase III, alpha subunit; Belongs to the DNA polymerase type-C family. DnaE2 subfamily. (1177 aa) |
| | AGS68661.1 | ADP-ribose pyrophosphatase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (208 aa) |
| | AGS68668.1 | DNA recombination and repair protein; May be involved in recombinational repair of damaged DNA. (580 aa) |
| | AGS68679.1 | COG2094 3-methyladenine DNA glycosylase; Belongs to the DNA glycosylase MPG family. (216 aa) |
| | uvrC | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (682 aa) |
| | uvrA | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (1016 aa) |
| | AGS68862.1 | COG0491 Zn-dependent hydrolases, including glyoxylases. (218 aa) |
| | uvrB | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (714 aa) |
| | AGS68875.1 | methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (184 aa) |
| | AGS68895.1 | Hypothetical protein; COG1573 Uracil-DNA glycosylase. (258 aa) |
| | AGS68896.1 | Hypothetical protein; COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog). (209 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (908 aa) |
| | AGS68923.1 | Hypothetical protein. (231 aa) |
| | AGS69023.1 | Hypothetical protein. (186 aa) |
| | nfo | Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (274 aa) |
| | AGS69137.1 | Hypothetical protein. (393 aa) |
| | AGS69232.1 | Hypothetical protein. (279 aa) |
| | AGS69283.1 | Hypothetical protein. (214 aa) |
| | AGS69311.1 | COG1680 Beta-lactamase class C and other penicillin binding proteins. (273 aa) |
| | AGS69382.1 | Hypothetical protein. (492 aa) |
| | recO | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (248 aa) |
| | AGS69522.1 | COG1555 DNA uptake protein and related DNA-binding proteins. (410 aa) |
| | AGS69601.1 | Endonuclease VIII and DNA N-glycosylase with an AP lyase activity; COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (269 aa) |
| | AGS69615.1 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (215 aa) |
| | recD2 | Deoxyribonuclease; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (731 aa) |
| | AGS69752.1 | COG2375 Siderophore-interacting protein. (280 aa) |
| | AGS69942.1 | COG3214 Uncharacterized protein conserved in bacteria. (400 aa) |
| | AGS69973.1 | Hypothetical protein; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. (336 aa) |
| | mfd | Transcriptional-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1177 aa) |
| | AGS70109.1 | COG0708 Exonuclease III. (264 aa) |
| | AGS70156.1 | COG3950 Predicted ATP-binding protein involved in virulence. (454 aa) |
| | AGS70166.1 | Hypothetical protein. (213 aa) |
| | AGS70357.1 | COG1329 Transcriptional regulators, similar to M. xanthus CarD. (160 aa) |
| | AGS70408.1 | Hypothetical protein; May play a role in the intracellular transport of hydrophobic ligands. (191 aa) |
| | AGS70432.1 | Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (137 aa) |
| | AGS70474.1 | COG0513 Superfamily II DNA and RNA helicases. (727 aa) |
| | AGS70493.1 | LSR2-like protein. (105 aa) |
| | AGS70512.1 | Hypothetical protein; COG0177 Predicted EndoIII-related endonuclease. (206 aa) |
| | AGS70555.1 | Hypothetical protein. (288 aa) |
| | AGS70571.1 | COG2847 Uncharacterized protein conserved in bacteria. (155 aa) |
| | AGS70636.1 | COG0492 Thioredoxin reductase. (323 aa) |
| | recF | Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (373 aa) |
| | AGS70710.1 | DNA-binding protein; COG3617 Prophage antirepressor. (343 aa) |
| | clpB | ATP-dependent protease ATP-binding subunit; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (865 aa) |
| | recR | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (199 aa) |
| | AGS70860.1 | COG0178 Excinuclease ATPase subunit. (794 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (330 aa) |
| | AGS70910.1 | ATP-dependent RNA helicase; COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster. (780 aa) |
| | AGS70927.1 | COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains. (561 aa) |
| | AGS70978.1 | Lsr2-like protein. (111 aa) |
| | AGS70989.1 | COG1194 A/G-specific DNA glycosylase. (291 aa) |
| | disA | DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis. (352 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (469 aa) |
| | AGS71087.1 | DNA polymerase related protein; COG1573 Uracil-DNA glycosylase. (219 aa) |
| | AGS71161.1 | COG1666 Uncharacterized protein conserved in bacteria; Belongs to the UPF0234 family. (162 aa) |
| | AGS71404.1 | Hypothetical protein. (110 aa) |
| | AGS71593.1 | Hypothetical protein. (63 aa) |
| | AGS71594.1 | mutT-like protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. (142 aa) |
| | AGS71646.1 | COG2818 3-methyladenine DNA glycosylase. (196 aa) |
| | AGS71672.1 | COG0513 Superfamily II DNA and RNA helicases. (876 aa) |
| | AGS71692.1 | COG3695 Predicted methylated DNA-protein cysteine methyltransferase. (147 aa) |
| | AGS71693.1 | COG0210 Superfamily I DNA and RNA helicases; Belongs to the helicase family. UvrD subfamily. (1161 aa) |
| | AGS71694.1 | COG0210 Superfamily I DNA and RNA helicases; Belongs to the helicase family. UvrD subfamily. (1189 aa) |
| | AGS71725.1 | Hypothetical protein; Belongs to the SOS response-associated peptidase family. (271 aa) |
| | AGS71761.1 | Superoxide dismutase, Ni; COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase. (131 aa) |
| | lon | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (806 aa) |
| | AGS71808.1 | DNA ligase; COG3285 Predicted eukaryotic-type DNA primase. (281 aa) |
| | ku | Hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (370 aa) |
| | ku-2 | Ku70/Ku80 protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (329 aa) |
| | ligA | NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (731 aa) |
| | AGS72038.1 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. (608 aa) |
| | mutM | Formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (286 aa) |
| | AGS72049.1 | Hypothetical protein. (341 aa) |
| | AGS72196.1 | DNA glycosylase; COG0266 Formamidopyrimidine-DNA glycosylase. (284 aa) |
| | AGS72197.1 | ATP-dependent DNA helicase; COG1201 Lhr-like helicases. (1668 aa) |
| | recA | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (374 aa) |
| | lexA | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (234 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (233 aa) |
| | AGS72304.1 | Hypothetical protein; COG0183 Acetyl-CoA acetyltransferase. (116 aa) |
| | AGS72321.1 | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (156 aa) |
| | AGS72348.1 | bldA-regulated nucleotide binding protein; COG0488 ATPase components of ABC transporters with duplicated ATPase domains. (409 aa) |
| | AGS72584.1 | ADA-like regulatory protein; COG2169 Adenosine deaminase. (472 aa) |
| | AGS72607.1 | Hypothetical protein. (173 aa) |
| | AGS72689.1 | COG0708 Exonuclease III. (259 aa) |
| | AGS72733.1 | ADA-like regulatory protein; COG2169 Adenosine deaminase. (499 aa) |
| | AGS72734.1 | methylated-DNA--protein-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (163 aa) |
| | AGS72766.1 | Hypothetical protein; COG1533 DNA repair photolyase. (351 aa) |
| | AGS72829.1 | Hypothetical protein. (203 aa) |
| | ligC | COG1793 ATP-dependent DNA ligase. (354 aa) |
| | AGS72929.1 | Hypothetical protein; COG3285 Predicted eukaryotic-type DNA primase. (347 aa) |
| | nfi | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (379 aa) |
| | AGS73093.1 | DEAD/DEAH box helicase; COG0513 Superfamily II DNA and RNA helicases. (523 aa) |
| | AGS73094.1 | COG0513 Superfamily II DNA and RNA helicases. (472 aa) |
| | AGS73114.1 | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (822 aa) |
| | AGS73173.1 | COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (287 aa) |
| | AGS73197.1 | COG0178 Excinuclease ATPase subunit. (776 aa) |
| | AGS73321.1 | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (190 aa) |
| | AGS73397.1 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. (650 aa) |
| | AGS73402.1 | COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (118 aa) |
| | AGS73444.1 | COG0071 Molecular chaperone (small heat shock protein). (143 aa) |
| | AGS73581.1 | COG0071 Molecular chaperone (small heat shock protein). (143 aa) |
| | AGS73717.1 | Hypothetical protein. (365 aa) |
