STRINGSTRING
AGS73406.1 AGS73406.1 AGS73440.1 AGS73440.1 AGS67232.1 AGS67232.1 AGS67255.1 AGS67255.1 AGS67289.1 AGS67289.1 AGS67326.1 AGS67326.1 AGS67385.1 AGS67385.1 AGS67386.1 AGS67386.1 AGS67480.1 AGS67480.1 AGS67710.1 AGS67710.1 add add AGS67879.1 AGS67879.1 AGS67931.1 AGS67931.1 AGS68072.1 AGS68072.1 ureC1 ureC1 ureB ureB ureA ureA AGS68216.1 AGS68216.1 AGS68296.1 AGS68296.1 AGS68402.1 AGS68402.1 AGS68508.1 AGS68508.1 AGS68924.1 AGS68924.1 AGS69167.1 AGS69167.1 AGS72835.1 AGS72835.1 AGS69174.1 AGS69174.1 AGS69206.1 AGS69206.1 AGS69258.1 AGS69258.1 AGS73021.1 AGS73021.1 AGS69365.1 AGS69365.1 AGS69437.1 AGS69437.1 AGS69449.1 AGS69449.1 AGS69480.1 AGS69480.1 AGS69488.1 AGS69488.1 AGS73462.1 AGS73462.1 AGS69489.1 AGS69489.1 AGS69493.1 AGS69493.1 AGS69737.1 AGS69737.1 AGS69792.1 AGS69792.1 AGS69839.1 AGS69839.1 rph rph AGS70036.1 AGS70036.1 AGS70226.1 AGS70226.1 AGS70346.1 AGS70346.1 AGS70424.1 AGS70424.1 AGS70453.1 AGS70453.1 AGS70474.1 AGS70474.1 AGS70657.1 AGS70657.1 AGS70792.1 AGS70792.1 kynA kynA kynU kynU AGS70836.1 AGS70836.1 AGS71052.1 AGS71052.1 AGS71400.1 AGS71400.1 add-2 add-2 AGS71422.1 AGS71422.1 xseB xseB xseA xseA AGS71547.1 AGS71547.1 AGS71557.1 AGS71557.1 AGS71672.1 AGS71672.1 AGS71696.1 AGS71696.1 AGS71859.1 AGS71859.1 ureAB ureAB ureC2 ureC2 pnp pnp AGS72243.1 AGS72243.1 rnhB rnhB dut dut AGS72349.1 AGS72349.1 AGS72599.1 AGS72599.1 AGS72603.1 AGS72603.1 AGS72664.1 AGS72664.1 alc alc AGS73068.1 AGS73068.1 AGS73093.1 AGS73093.1 AGS73094.1 AGS73094.1 AGS73296.1 AGS73296.1 AGS73356.1 AGS73356.1 AGS73376.1 AGS73376.1 AGS73379.1 AGS73379.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGS73406.1COG2367 Beta-lactamase class A. (309 aa)
AGS73440.1Isochorismatase hydrolase; COG1335 Amidases related to nicotinamidase. (199 aa)
AGS67232.1Metallo-beta-lactamase superfamily protein; COG0491 Zn-dependent hydrolases, including glyoxylases. (248 aa)
AGS67255.1Isochorismatase hydrolase; COG1335 Amidases related to nicotinamidase. (199 aa)
AGS67289.1COG2367 Beta-lactamase class A. (309 aa)
AGS67326.1Isochorismatase; COG1335 Amidases related to nicotinamidase. (173 aa)
AGS67385.1Hypothetical protein. (194 aa)
AGS67386.1Putative regulatory protein; COG2319 FOG: WD40 repeat. (356 aa)
AGS67480.1Hypothetical protein; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs. (239 aa)
AGS67710.1Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (202 aa)
addCOG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (359 aa)
AGS67879.1Putative oxidoreductase; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs. (275 aa)
AGS67931.1Metallo-beta-lactamase-like protein; COG0491 Zn-dependent hydrolases, including glyoxylases. (238 aa)
AGS68072.1Putative peptidase M38 family protein; COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold. (539 aa)
ureC1Urease subunit alpha; COG0804 Urea amidohydrolase (urease) alpha subunit. (573 aa)
ureBUrease subunit beta; COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family. (103 aa)
ureAUrease subunit gamma; COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family. (100 aa)
AGS68216.1Hypothetical protein; COG1335 Amidases related to nicotinamidase. (214 aa)
AGS68296.1Hypothetical protein; COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold. (537 aa)
AGS68402.1HIT family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. (182 aa)
AGS68508.1Helicase; COG4581 Superfamily II RNA helicase. (935 aa)
AGS68924.12',3'-cyclic-nucleotide 2'-phosphodiesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. (601 aa)
AGS69167.1Secreted acid phosphatase. (295 aa)
AGS72835.1Isochorismatase; COG1335 Amidases related to nicotinamidase. (170 aa)
AGS69174.1Putative hydrolase; COG0515 Serine/threonine protein kinase. (188 aa)
AGS69206.1COG5398 Heme oxygenase. (215 aa)
AGS69258.1Hypothetical protein; COG0491 Zn-dependent hydrolases, including glyoxylases. (342 aa)
AGS73021.1Hypothetical protein. (695 aa)
AGS69365.1Deoxyguanosinetriphosphate triphosphohydrolase-like protein; COG0232 dGTP triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily. (424 aa)
AGS69437.1Hypothetical protein. (117 aa)
AGS69449.1Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (330 aa)
AGS69480.1Polyketide cyclase; COG1878 Predicted metal-dependent hydrolase. (256 aa)
AGS69488.1COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (497 aa)
AGS73462.1Metallo-beta-lactamase superfamily protein; COG0491 Zn-dependent hydrolases, including glyoxylases. (248 aa)
AGS69489.1acyl-CoA ligase; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides. (187 aa)
AGS69493.1Hypothetical protein; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides. (223 aa)
AGS69737.1Hypothetical protein; COG2367 Beta-lactamase class A. (299 aa)
AGS69792.1Amidase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Belongs to the amidase family. (462 aa)
AGS69839.1dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (200 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (245 aa)
AGS70036.1Nucleoside triphosphate pyrophosphohydrolase; COG1694 Predicted pyrophosphatase. (331 aa)
AGS70226.1Cyclase; COG1878 Predicted metal-dependent hydrolase. (311 aa)
AGS70346.1Polyketide-based spore pigment synthesis protein; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides. (346 aa)
AGS70424.1COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. (597 aa)
AGS70453.1Isochorismatase; COG1335 Amidases related to nicotinamidase. (185 aa)
AGS70474.1COG0513 Superfamily II DNA and RNA helicases. (727 aa)
AGS70657.1WD-40 repeat-containing protein; COG2319 FOG: WD40 repeat. (1462 aa)
AGS70792.1Antibiotic biosynthesis monooxygenase; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides. (108 aa)
kynATryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (282 aa)
kynUHydrolase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (394 aa)
AGS70836.1COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. (600 aa)
AGS71052.1Cyclase; COG0009 Putative translation factor (SUA5). (321 aa)
AGS71400.1COG0295 Cytidine deaminase. (133 aa)
add-2COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (377 aa)
AGS71422.1Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (319 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (74 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (406 aa)
AGS71547.1Addiction module antitoxin; COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system. (77 aa)
AGS71557.1Flavin reductase; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family. (148 aa)
AGS71672.1COG0513 Superfamily II DNA and RNA helicases. (876 aa)
AGS71696.1Hypothetical protein; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding. (314 aa)
AGS71859.1COG1250 3-hydroxyacyl-CoA dehydrogenase. (282 aa)
ureABCOG0831 Urea amidohydrolase (urease) gamma subunit; In the C-terminal section; belongs to the urease beta subunit family. (241 aa)
ureC2Urease subunit alpha; COG0804 Urea amidohydrolase (urease) alpha subunit. (574 aa)
pnpPolynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (740 aa)
AGS72243.1Hypothetical protein. (156 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (233 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (192 aa)
AGS72349.1Hypothetical protein; COG1694 Predicted pyrophosphatase. (114 aa)
AGS72599.1Dehydrogenase; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs. (297 aa)
AGS72603.1Hypothetical protein; COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family. (384 aa)
AGS72664.1Allantoinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. (446 aa)
alcCOG4266 Allantoicase; Belongs to the allantoicase family. (379 aa)
AGS73068.1Oxidoreductase, molybdopterin binding subunit; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs. (331 aa)
AGS73093.1DEAD/DEAH box helicase; COG0513 Superfamily II DNA and RNA helicases. (523 aa)
AGS73094.1COG0513 Superfamily II DNA and RNA helicases. (472 aa)
AGS73296.1COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold. (543 aa)
AGS73356.1Hydrolase; COG1335 Amidases related to nicotinamidase. (194 aa)
AGS73376.1COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family. (368 aa)
AGS73379.1FAD-binding molybdopterin dehydrogenase protein; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs. (284 aa)
Your Current Organism:
Streptomyces collinus
NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365
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