(37 nodes) Histidine kinase domain network (Streptomyces collinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AGS68446.1	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase. (517 aa)
	AGS73074.1	Two-component system sensor kinase; COG3275 Putative regulator of cell autolysis. (397 aa)
	AGS72656.1	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase. (525 aa)
	AGS72434.1	COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism. (544 aa)
	AGS72302.1	Two-component system sensor kinase; COG2205 Osmosensitive K+ channel histidine kinase. (858 aa)
	AGS72295.1	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase. (415 aa)
	AGS72270.1	Two-component sensor; COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism. (536 aa)
	AGS72216.1	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase. (475 aa)
	AGS72185.1	Two-component system sensor kinase; COG2770 FOG: HAMP domain. (1791 aa)
	AGS72015.1	COG0642 Signal transduction histidine kinase. (1220 aa)
	AGS71899.1	Two-component sensor kinase; COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism. (542 aa)
	AGS71855.1	Putative two-component system sensor kinase; COG0642 Signal transduction histidine kinase. (487 aa)
	AGS71804.1	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase. (416 aa)
	AGS71791.1	COG0642 Signal transduction histidine kinase. (964 aa)
	AGS71781.1	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase. (373 aa)
	AGS71742.1	Two-component system sensor kinase; COG3920 Signal transduction histidine kinase. (488 aa)
	AGS71415.1	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase. (533 aa)
	AGS71061.1	ATPase domain-containing protein; COG0642 Signal transduction histidine kinase. (505 aa)
	AGS71046.1	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase. (492 aa)
	AGS70985.1	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase. (452 aa)
	AGS70965.1	Two-component system sensor kinase; COG4585 Signal transduction histidine kinase. (401 aa)
	AGS70760.1	Two-component system sensor kinase; COG5002 Signal transduction histidine kinase. (370 aa)
	AGS70537.1	Two component system histidine kinase; COG0642 Signal transduction histidine kinase. (544 aa)
	AGS70423.1	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase. (487 aa)
	AGS70360.1	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase. (417 aa)
	AGS69995.1	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase. (424 aa)
	AGS69947.1	COG0642 Signal transduction histidine kinase. (670 aa)
	AGS69773.1	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase. (458 aa)
	AGS68689.1	Two-component system sensor kinase; COG2203 FOG: GAF domain. (381 aa)
	AGS68479.1	Two-component system sensor kinase; COG5002 Signal transduction histidine kinase. (375 aa)
	AGS68006.1	COG0642 Signal transduction histidine kinase. (820 aa)
	AGS67690.1	COG0642 Signal transduction histidine kinase. (494 aa)
	AGS67679.1	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase. (614 aa)
	AGS67589.1	Two-component system sensor kinase; COG2770 FOG: HAMP domain. (1418 aa)
	AGS67199.1	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase. (484 aa)
	AGS67101.1	Two-component sensor; COG0642 Signal transduction histidine kinase. (442 aa)
	AGS66946.1	Histidine kinase; COG0642 Signal transduction histidine kinase. (659 aa)

Your Current Organism:

Streptomyces collinus

NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGS66946.1	AGS67101.1	B446_00530	B446_01325	Histidine kinase; COG0642 Signal transduction histidine kinase.	Two-component sensor; COG0642 Signal transduction histidine kinase.	0.417
AGS66946.1	AGS67199.1	B446_00530	B446_01835	Histidine kinase; COG0642 Signal transduction histidine kinase.	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase.	0.415
AGS66946.1	AGS67589.1	B446_00530	B446_03785	Histidine kinase; COG0642 Signal transduction histidine kinase.	Two-component system sensor kinase; COG2770 FOG: HAMP domain.	0.505
AGS66946.1	AGS67690.1	B446_00530	B446_04310	Histidine kinase; COG0642 Signal transduction histidine kinase.	COG0642 Signal transduction histidine kinase.	0.461
AGS66946.1	AGS70360.1	B446_00530	B446_17720	Histidine kinase; COG0642 Signal transduction histidine kinase.	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase.	0.408
AGS66946.1	AGS71061.1	B446_00530	B446_21245	Histidine kinase; COG0642 Signal transduction histidine kinase.	ATPase domain-containing protein; COG0642 Signal transduction histidine kinase.	0.534
AGS66946.1	AGS71855.1	B446_00530	B446_25220	Histidine kinase; COG0642 Signal transduction histidine kinase.	Putative two-component system sensor kinase; COG0642 Signal transduction histidine kinase.	0.494
AGS66946.1	AGS72185.1	B446_00530	B446_26885	Histidine kinase; COG0642 Signal transduction histidine kinase.	Two-component system sensor kinase; COG2770 FOG: HAMP domain.	0.998
AGS67101.1	AGS66946.1	B446_01325	B446_00530	Two-component sensor; COG0642 Signal transduction histidine kinase.	Histidine kinase; COG0642 Signal transduction histidine kinase.	0.417
AGS67101.1	AGS68479.1	B446_01325	B446_08275	Two-component sensor; COG0642 Signal transduction histidine kinase.	Two-component system sensor kinase; COG5002 Signal transduction histidine kinase.	0.517
AGS67101.1	AGS71046.1	B446_01325	B446_21170	Two-component sensor; COG0642 Signal transduction histidine kinase.	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase.	0.570
AGS67101.1	AGS71061.1	B446_01325	B446_21245	Two-component sensor; COG0642 Signal transduction histidine kinase.	ATPase domain-containing protein; COG0642 Signal transduction histidine kinase.	0.668
AGS67101.1	AGS72185.1	B446_01325	B446_26885	Two-component sensor; COG0642 Signal transduction histidine kinase.	Two-component system sensor kinase; COG2770 FOG: HAMP domain.	0.979
AGS67199.1	AGS66946.1	B446_01835	B446_00530	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase.	Histidine kinase; COG0642 Signal transduction histidine kinase.	0.415
AGS67199.1	AGS71046.1	B446_01835	B446_21170	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase.	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase.	0.404
AGS67199.1	AGS71804.1	B446_01835	B446_24965	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase.	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase.	0.521
AGS67199.1	AGS72185.1	B446_01835	B446_26885	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase.	Two-component system sensor kinase; COG2770 FOG: HAMP domain.	0.948
AGS67589.1	AGS66946.1	B446_03785	B446_00530	Two-component system sensor kinase; COG2770 FOG: HAMP domain.	Histidine kinase; COG0642 Signal transduction histidine kinase.	0.505
AGS67589.1	AGS72185.1	B446_03785	B446_26885	Two-component system sensor kinase; COG2770 FOG: HAMP domain.	Two-component system sensor kinase; COG2770 FOG: HAMP domain.	0.889
AGS67679.1	AGS72185.1	B446_04255	B446_26885	Two-component system sensor kinase; COG0642 Signal transduction histidine kinase.	Two-component system sensor kinase; COG2770 FOG: HAMP domain.	0.979