STRINGSTRING
AGS71859.1 AGS71859.1 ilvC ilvC gpsA gpsA AGS72459.1 AGS72459.1 AGS73151.1 AGS73151.1 AGS72635.1 AGS72635.1 AGS72881.1 AGS72881.1 AGS72762.1 AGS72762.1 AGS72886.1 AGS72886.1 AGS67463.1 AGS67463.1 AGS68471.1 AGS68471.1 AGS68650.1 AGS68650.1 AGS69287.1 AGS69287.1 AGS69987.1 AGS69987.1 AGS70098.1 AGS70098.1 AGS70649.1 AGS70649.1 AGS72946.1 AGS72946.1 AGS70692.1 AGS70692.1 AGS70969.1 AGS70969.1 proC proC AGS71291.1 AGS71291.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGS71859.1COG1250 3-hydroxyacyl-CoA dehydrogenase. (282 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa)
gpsACOG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (336 aa)
AGS72459.1Fatty acid oxidation complex alpha-subunit; COG1024 Enoyl-CoA hydratase/carnithine racemase. (709 aa)
AGS73151.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (479 aa)
AGS72635.12-hydroxy-3-oxopropionate reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases. (297 aa)
AGS72881.1NADP oxidoreductase, coenzyme F420-dependent:6-phosphogluconate dehydrogenase, NAD-binding protein; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases. (311 aa)
AGS72762.1Oxidoreductase; COG1250 3-hydroxyacyl-CoA dehydrogenase. (604 aa)
AGS72886.1COG1023 Predicted 6-phosphogluconate dehydrogenase. (292 aa)
AGS67463.1COG1250 3-hydroxyacyl-CoA dehydrogenase. (300 aa)
AGS68471.1COG1250 3-hydroxyacyl-CoA dehydrogenase. (277 aa)
AGS68650.1COG0287 Prephenate dehydrogenase. (361 aa)
AGS69287.1Oxidoreductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (299 aa)
AGS69987.1COG1004 Predicted UDP-glucose 6-dehydrogenase. (447 aa)
AGS70098.1Dehydrogenase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases. (301 aa)
AGS70649.16-phosphogluconate dehydrogenase-like protein; COG1023 Predicted 6-phosphogluconate dehydrogenase. (291 aa)
AGS72946.1Fatty acid oxidative multifunctional enzyme; COG1024 Enoyl-CoA hydratase/carnithine racemase. (727 aa)
AGS70692.1COG1250 3-hydroxyacyl-CoA dehydrogenase. (504 aa)
AGS70969.1Hypothetical protein. (318 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)
AGS71291.1COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (402 aa)
Your Current Organism:
Streptomyces collinus
NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365
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