STRINGSTRING
AGS73103.1 AGS73103.1 AGS66875.1 AGS66875.1 AGS67012.1 AGS67012.1 AGS67688.1 AGS67688.1 AGS67741.1 AGS67741.1 AGS67754.1 AGS67754.1 AGS67800.1 AGS67800.1 AGS67883.1 AGS67883.1 AGS67938.1 AGS67938.1 AGS67939.1 AGS67939.1 AGS67983.1 AGS67983.1 AGS68060.1 AGS68060.1 mshC mshC tyrS tyrS ileS ileS nadE nadE AGS69367.1 AGS69367.1 leuS leuS nadD nadD valS valS AGS69763.1 AGS69763.1 AGS73181.1 AGS73181.1 cysS cysS metG metG metG-2 metG-2 tilS tilS panC panC trpS trpS argS argS lysK lysK AGS71174.1 AGS71174.1 guaA guaA trpS-2 trpS-2 mnmA mnmA gltX gltX coaD coaD AGS72153.1 AGS72153.1 AGS72302.1 AGS72302.1 AGS72485.1 AGS72485.1 AGS72547.1 AGS72547.1 AGS72549.1 AGS72549.1 argG argG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGS73103.1COG0143 Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (543 aa)
AGS66875.1Hypothetical protein; COG0603 Predicted PP-loop superfamily ATPase. (445 aa)
AGS67012.1Hypothetical protein; COG0367 Asparagine synthase (glutamine-hydrolyzing). (592 aa)
AGS67688.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (288 aa)
AGS67741.1COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. (458 aa)
AGS67754.1COG0367 Asparagine synthase (glutamine-hydrolyzing). (613 aa)
AGS67800.1Bifunctional synthase/transferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (479 aa)
AGS67883.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (292 aa)
AGS67938.1COG2025 Electron transfer flavoprotein, alpha subunit. (320 aa)
AGS67939.1COG2086 Electron transfer flavoprotein, beta subunit. (261 aa)
AGS67983.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (301 aa)
AGS68060.1Cytidyltransferase-related domain-containing protein; COG0615 Cytidylyltransferase. (155 aa)
mshCcysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (409 aa)
tyrStyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (422 aa)
ileSisoleucyl-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1047 aa)
nadENAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (679 aa)
AGS69367.1COG2949 Uncharacterized membrane protein. (225 aa)
leuSCOG0495 Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (960 aa)
nadDNicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (188 aa)
valSvalyl-tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (876 aa)
AGS69763.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (175 aa)
AGS73181.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (156 aa)
cysSCOG0215 Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (466 aa)
metGmethionyl-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (532 aa)
metG-2methionyl-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (571 aa)
tilStRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (354 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (333 aa)
trpStryptophanyl-tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (341 aa)
argSCOG0018 Arginyl-tRNA synthetase. (589 aa)
lysKCOG1384 Lysyl-tRNA synthetase (class I); Belongs to the class-I aminoacyl-tRNA synthetase family. (579 aa)
AGS71174.1Hypothetical protein. (224 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (526 aa)
trpS-2tryptophanyl-tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (338 aa)
mnmAtRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (376 aa)
gltXglutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (475 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (159 aa)
AGS72153.1Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family. (315 aa)
AGS72302.1Two-component system sensor kinase; COG2205 Osmosensitive K+ channel histidine kinase. (858 aa)
AGS72485.1Hypothetical protein. (157 aa)
AGS72547.1Sulfate adenylyltransferase subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes. (313 aa)
AGS72549.1Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (239 aa)
argGCOG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (482 aa)
Your Current Organism:
Streptomyces collinus
NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365
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