STRINGSTRING
AGS72235.1 AGS72235.1 AGS72398.1 AGS72398.1 AGS72432.1 AGS72432.1 AGS72648.1 AGS72648.1 AGS72699.1 AGS72699.1 AGS72807.1 AGS72807.1 AGS72979.1 AGS72979.1 AGS73087.1 AGS73087.1 kbl kbl AGS67027.1 AGS67027.1 AGS67229.1 AGS67229.1 AGS67238.1 AGS67238.1 AGS67312.1 AGS67312.1 AGS67396.1 AGS67396.1 selA selA AGS67616.1 AGS67616.1 AGS67944.1 AGS67944.1 AGS68099.1 AGS68099.1 AGS68125.1 AGS68125.1 AGS73100.1 AGS73100.1 bioA bioA AGS68151.1 AGS68151.1 AGS68156.1 AGS68156.1 AGS68220.1 AGS68220.1 gcvP gcvP AGS68289.1 AGS68289.1 argD argD AGS68467.1 AGS68467.1 AGS68756.1 AGS68756.1 AGS68762.1 AGS68762.1 AGS68764.1 AGS68764.1 AGS68767.1 AGS68767.1 AGS68818.1 AGS68818.1 AGS68926.1 AGS68926.1 hisC hisC AGS69069.1 AGS69069.1 AGS69080.1 AGS69080.1 AGS69336.1 AGS69336.1 AGS69515.1 AGS69515.1 AGS69753.1 AGS69753.1 serC serC AGS70565.1 AGS70565.1 pat pat AGS70605.1 AGS70605.1 AGS70736.1 AGS70736.1 AGS70783.1 AGS70783.1 AGS70784.1 AGS70784.1 AGS70808.1 AGS70808.1 kynU kynU AGS70843.1 AGS70843.1 AGS70940.1 AGS70940.1 AGS70968.1 AGS70968.1 AGS71025.1 AGS71025.1 hemL hemL AGS71201.1 AGS71201.1 AGS71350.1 AGS71350.1 glyA-2 glyA-2 AGS71454.1 AGS71454.1 AGS71478.1 AGS71478.1 AGS71639.1 AGS71639.1 glyA-3 glyA-3 glyA glyA AGS71955.1 AGS71955.1 AGS72110.1 AGS72110.1 AGS72130.1 AGS72130.1 AGS72183.1 AGS72183.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGS72235.1Class III aminotransferase; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (493 aa)
AGS72398.1COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (432 aa)
AGS72432.1COG0520 Selenocysteine lyase. (541 aa)
AGS72648.1Aminotransferase AlaT; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (402 aa)
AGS72699.1Class III aminotransferase; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa)
AGS72807.1Hypothetical protein; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (418 aa)
AGS72979.1Aminotransferase; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (461 aa)
AGS73087.1COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (341 aa)
kbl2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (399 aa)
AGS67027.1Class I and II aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (434 aa)
AGS67229.1Class V aminotransferase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. (396 aa)
AGS67238.1COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (473 aa)
AGS67312.1Amino acid decarboxylase; COG1982 Arginine/lysine/ornithine decarboxylases. (492 aa)
AGS67396.1Hypothetical protein; COG0520 Selenocysteine lyase. (370 aa)
selASelenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (422 aa)
AGS67616.1Aminotransferase; COG0001 Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
AGS67944.1Aldolase; COG2008 Threonine aldolase. (356 aa)
AGS68099.1COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (408 aa)
AGS68125.18-amino-7-oxononanoate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. (375 aa)
AGS73100.1COG2008 Threonine aldolase. (399 aa)
bioAAdenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (429 aa)
AGS68151.1COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (480 aa)
AGS68156.1COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (399 aa)
AGS68220.1COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (407 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (961 aa)
AGS68289.1COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (501 aa)
argDCOG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (405 aa)
AGS68467.1COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (440 aa)
AGS68756.1Hypothetical protein; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (363 aa)
AGS68762.1COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase. (366 aa)
AGS68764.1Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (423 aa)
AGS68767.1Hypothetical protein; COG0520 Selenocysteine lyase. (356 aa)
AGS68818.1Aminotransferase; COG0520 Selenocysteine lyase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (418 aa)
AGS68926.1Amino acid decarboxylase; COG0076 Glutamate decarboxylase and related PLP-dependent proteins. (452 aa)
hisCCOG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (368 aa)
AGS69069.1Pyridoxalphosphate-dependent protein; COG0520 Selenocysteine lyase. (459 aa)
AGS69080.1Pyridoxalphosphate dependent protein; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Belongs to the sulfur carrier protein TusA family. (462 aa)
AGS69336.1Aminotransferase; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (591 aa)
AGS69515.1Lipopolysaccharide biosynthesis protein RfbH; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family. (433 aa)
AGS69753.1Decarboxylase; COG0076 Glutamate decarboxylase and related PLP-dependent proteins. (480 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (372 aa)
AGS70565.1COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (454 aa)
patAminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (359 aa)
AGS70605.1COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (382 aa)
AGS70736.1COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (450 aa)
AGS70783.1COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family. (439 aa)
AGS70784.1Hypothetical protein; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis. (209 aa)
AGS70808.1Aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (391 aa)
kynUHydrolase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (394 aa)
AGS70843.1Hypothetical protein; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
AGS70940.1COG0076 Glutamate decarboxylase and related PLP-dependent proteins; Belongs to the group II decarboxylase family. (468 aa)
AGS70968.1COG2008 Threonine aldolase. (402 aa)
AGS71025.1Aminotransferase; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (401 aa)
hemLCOG0001 Glutamate-1-semialdehyde aminotransferase. (439 aa)
AGS71201.1COG0436 Aspartate/tyrosine/aromatic aminotransferase. (408 aa)
AGS71350.1COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (474 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (483 aa)
AGS71454.1COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (384 aa)
AGS71478.1Aminotransferase AlaT; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (403 aa)
AGS71639.1COG0436 Aspartate/tyrosine/aromatic aminotransferase. (365 aa)
glyA-3Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (425 aa)
AGS71955.1Pyridoxal-phosphate-dependent aminotransferase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. (389 aa)
AGS72110.1Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
AGS72130.1COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
AGS72183.1Hypothetical protein; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis. (220 aa)
Your Current Organism:
Streptomyces collinus
NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365
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