(6 nodes) Dihydrofolate reductase-like domain superfamily network (Streptomyces collinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AGS71755.1	Hypothetical protein; COG0262 Dihydrofolate reductase. (194 aa)
	AGS67309.1	Bifunctional deaminase-reductase domain-containing protein; COG0262 Dihydrofolate reductase. (187 aa)
	AGS67405.1	Hypothetical protein; COG0262 Dihydrofolate reductase. (215 aa)
	AGS69566.1	Hypothetical protein; COG0262 Dihydrofolate reductase. (190 aa)
	AGS70469.1	Bifunctional deaminase/reductase-like protein; COG1985 Pyrimidine reductase, riboflavin biosynthesis. (377 aa)
	AGS72484.1	Hypothetical protein; COG1985 Pyrimidine reductase, riboflavin biosynthesis. (266 aa)

Your Current Organism:

Streptomyces collinus

NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGS67309.1	AGS67405.1	B446_02385	B446_02865	Bifunctional deaminase-reductase domain-containing protein; COG0262 Dihydrofolate reductase.	Hypothetical protein; COG0262 Dihydrofolate reductase.	0.521
AGS67309.1	AGS71755.1	B446_02385	B446_24720	Bifunctional deaminase-reductase domain-containing protein; COG0262 Dihydrofolate reductase.	Hypothetical protein; COG0262 Dihydrofolate reductase.	0.497
AGS67405.1	AGS67309.1	B446_02865	B446_02385	Hypothetical protein; COG0262 Dihydrofolate reductase.	Bifunctional deaminase-reductase domain-containing protein; COG0262 Dihydrofolate reductase.	0.521
AGS67405.1	AGS69566.1	B446_02865	B446_13740	Hypothetical protein; COG0262 Dihydrofolate reductase.	Hypothetical protein; COG0262 Dihydrofolate reductase.	0.410
AGS69566.1	AGS67405.1	B446_13740	B446_02865	Hypothetical protein; COG0262 Dihydrofolate reductase.	Hypothetical protein; COG0262 Dihydrofolate reductase.	0.410
AGS71755.1	AGS67309.1	B446_24720	B446_02385	Hypothetical protein; COG0262 Dihydrofolate reductase.	Bifunctional deaminase-reductase domain-containing protein; COG0262 Dihydrofolate reductase.	0.497