STRINGSTRING
AGS68913.1 AGS68913.1 AGS69878.1 AGS69878.1 mqnB mqnB mqnD mqnD AGS71082.1 AGS71082.1 ubiA ubiA AGS71084.1 AGS71084.1 mqnE mqnE mqnA mqnA mqnC mqnC ubiE ubiE AGS71139.1 AGS71139.1 AGS72048.1 AGS72048.1 AGS72118.1 AGS72118.1 AGS72339.1 AGS72339.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGS68913.1COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism. (163 aa)
AGS69878.1COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins. (382 aa)
mqnBHypothetical protein; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). (202 aa)
mqnDHypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (282 aa)
AGS71082.1Decarboxylase; COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family. (485 aa)
ubiAPrenyltransferase; COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; Belongs to the UbiA prenyltransferase family. (300 aa)
AGS71084.1Octaprenyl carboxylase; COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase. (198 aa)
mqnERadical SAM protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (387 aa)
mqnAHypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (282 aa)
mqnCHypothetical protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (404 aa)
ubiEUbiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (231 aa)
AGS71139.1Hypothetical protein; COG0702 Predicted nucleoside-diphosphate-sugar epimerases. (284 aa)
AGS72048.1Hypothetical protein; COG0655 Multimeric flavodoxin WrbA. (194 aa)
AGS72118.1COG1816 Adenosine deaminase. (356 aa)
AGS72339.1Putative methyltransferase; COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis. (221 aa)
Your Current Organism:
Streptomyces collinus
NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.