23 items (Streptomyces collinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AGS67027.1	Class I and II aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (434 aa)
	AGS67028.1	Hypothetical protein. (237 aa)
	AGS67240.1	Mycothiol-dependent maleylpyruvate isomerase. (262 aa)
	AGS67475.1	COG1231 Monoamine oxidase. (435 aa)
	AGS67709.1	Tyrosinase. (273 aa)
	gabD1	Succinic semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases. (461 aa)
	AGS68595.1	COG1062 Zn-dependent alcohol dehydrogenases, class III. (360 aa)
	hmgA	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (437 aa)
	AGS68756.1	Hypothetical protein; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (363 aa)
	AGS68861.1	Mycothiol-dependent maleylpyruvate isomerase. (228 aa)
	hisC	COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (368 aa)
	AGS69154.1	Isomerase; COG3232 5-carboxymethyl-2-hydroxymuconate isomerase. (121 aa)
	AGS69236.1	Dehydrogenase; COG1062 Zn-dependent alcohol dehydrogenases, class III. (358 aa)
	AGS69679.1	Tyrosinase. (288 aa)
	AGS69878.1	COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins. (382 aa)
	AGS70223.1	COG1062 Zn-dependent alcohol dehydrogenases, class III. (349 aa)
	pat	Aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (359 aa)
	AGS71126.1	Fumarylacetoacetase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (405 aa)
	AGS71201.1	COG0436 Aspartate/tyrosine/aromatic aminotransferase. (408 aa)
	gabD2	Succinic semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (537 aa)
	AGS72519.1	COG3733 Cu2+-containing amine oxidase. (441 aa)
	AGS73087.1	COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (341 aa)
	AGS73121.1	COG1012 NAD-dependent aldehyde dehydrogenases. (415 aa)

Your Current Organism:

Streptomyces collinus

NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGS67027.1	AGS67028.1	B446_00945	B446_00950	Class I and II aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase.	Hypothetical protein.	0.773
AGS67027.1	AGS67709.1	B446_00945	B446_04405	Class I and II aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase.	Tyrosinase.	0.911
AGS67027.1	AGS68756.1	B446_00945	B446_09665	Class I and II aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase.	Hypothetical protein; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.	0.816
AGS67027.1	AGS69679.1	B446_00945	B446_14305	Class I and II aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase.	Tyrosinase.	0.900
AGS67027.1	AGS69878.1	B446_00945	B446_15300	Class I and II aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase.	COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins.	0.913
AGS67027.1	AGS71201.1	B446_00945	B446_21945	Class I and II aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase.	COG0436 Aspartate/tyrosine/aromatic aminotransferase.	0.919
AGS67027.1	AGS73087.1	B446_00945	B446_31415	Class I and II aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase.	COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.	0.837
AGS67027.1	hisC	B446_00945	B446_10770	Class I and II aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase.	COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.816
AGS67027.1	pat	B446_00945	B446_18890	Class I and II aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase.	Aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.	0.816
AGS67028.1	AGS67027.1	B446_00950	B446_00945	Hypothetical protein.	Class I and II aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase.	0.773
AGS67028.1	AGS67240.1	B446_00950	B446_02040	Hypothetical protein.	Mycothiol-dependent maleylpyruvate isomerase.	0.923
AGS67028.1	AGS68861.1	B446_00950	B446_10190	Hypothetical protein.	Mycothiol-dependent maleylpyruvate isomerase.	0.919
AGS67240.1	AGS67028.1	B446_02040	B446_00950	Mycothiol-dependent maleylpyruvate isomerase.	Hypothetical protein.	0.923
AGS67240.1	AGS68861.1	B446_02040	B446_10190	Mycothiol-dependent maleylpyruvate isomerase.	Mycothiol-dependent maleylpyruvate isomerase.	0.924
AGS67475.1	AGS68595.1	B446_03215	B446_08855	COG1231 Monoamine oxidase.	COG1062 Zn-dependent alcohol dehydrogenases, class III.	0.901
AGS67475.1	AGS69236.1	B446_03215	B446_12070	COG1231 Monoamine oxidase.	Dehydrogenase; COG1062 Zn-dependent alcohol dehydrogenases, class III.	0.901
AGS67475.1	AGS70223.1	B446_03215	B446_17035	COG1231 Monoamine oxidase.	COG1062 Zn-dependent alcohol dehydrogenases, class III.	0.901
AGS67475.1	AGS72519.1	B446_03215	B446_28565	COG1231 Monoamine oxidase.	COG3733 Cu2+-containing amine oxidase.	0.921
AGS67709.1	AGS67027.1	B446_04405	B446_00945	Tyrosinase.	Class I and II aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase.	0.911
AGS67709.1	AGS68756.1	B446_04405	B446_09665	Tyrosinase.	Hypothetical protein; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.	0.900