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nadK nadK gabD1 gabD1 ppnK ppnK nadA nadA nadE nadE nadD nadD AGS69790.1 AGS69790.1 AGS69867.1 AGS69867.1 AGS69868.1 AGS69868.1 AGS70424.1 AGS70424.1 AGS70971.1 AGS70971.1 AGS70972.1 AGS70972.1 gabD2 gabD2 AGS71425.1 AGS71425.1 AGS71696.1 AGS71696.1 AGS72191.1 AGS72191.1 AGS72735.1 AGS72735.1 AGS73121.1 AGS73121.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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nadKATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (357 aa)
gabD1Succinic semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases. (461 aa)
ppnKInorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (275 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (394 aa)
nadENAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (679 aa)
nadDNicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (188 aa)
AGS69790.1Decarboxylase; COG3473 Maleate cis-trans isomerase. (285 aa)
AGS69867.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (448 aa)
AGS69868.1Nicotinamidase; COG1335 Amidases related to nicotinamidase. (197 aa)
AGS70424.1COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. (597 aa)
AGS70971.1L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (553 aa)
AGS70972.1COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (325 aa)
gabD2Succinic semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (537 aa)
AGS71425.1Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (274 aa)
AGS71696.1Hypothetical protein; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding. (314 aa)
AGS72191.1COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. (181 aa)
AGS72735.1COG0846 NAD-dependent protein deacetylases, SIR2 family. (241 aa)
AGS73121.1COG1012 NAD-dependent aldehyde dehydrogenases. (415 aa)
Your Current Organism:
Streptomyces collinus
NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365
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