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ung ung ligB ligB AGS68139.1 AGS68139.1 ung-2 ung-2 AGS68679.1 AGS68679.1 AGS68895.1 AGS68895.1 polA polA nfo nfo AGS69601.1 AGS69601.1 AGS70109.1 AGS70109.1 nth nth AGS70927.1 AGS70927.1 AGS70989.1 AGS70989.1 AGS71087.1 AGS71087.1 AGS71646.1 AGS71646.1 ligA ligA mutM mutM AGS72196.1 AGS72196.1 AGS72584.1 AGS72584.1 AGS72689.1 AGS72689.1 AGS72733.1 AGS72733.1 AGS73173.1 AGS73173.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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unguracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (225 aa)
ligBATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (512 aa)
AGS68139.1COG3663 G:T/U mismatch-specific DNA glycosylase. (176 aa)
ung-2uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (227 aa)
AGS68679.1COG2094 3-methyladenine DNA glycosylase; Belongs to the DNA glycosylase MPG family. (216 aa)
AGS68895.1Hypothetical protein; COG1573 Uracil-DNA glycosylase. (258 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (908 aa)
nfoApurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (274 aa)
AGS69601.1Endonuclease VIII and DNA N-glycosylase with an AP lyase activity; COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (269 aa)
AGS70109.1COG0708 Exonuclease III. (264 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (330 aa)
AGS70927.1COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains. (561 aa)
AGS70989.1COG1194 A/G-specific DNA glycosylase. (291 aa)
AGS71087.1DNA polymerase related protein; COG1573 Uracil-DNA glycosylase. (219 aa)
AGS71646.1COG2818 3-methyladenine DNA glycosylase. (196 aa)
ligANAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (731 aa)
mutMFormamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (286 aa)
AGS72196.1DNA glycosylase; COG0266 Formamidopyrimidine-DNA glycosylase. (284 aa)
AGS72584.1ADA-like regulatory protein; COG2169 Adenosine deaminase. (472 aa)
AGS72689.1COG0708 Exonuclease III. (259 aa)
AGS72733.1ADA-like regulatory protein; COG2169 Adenosine deaminase. (499 aa)
AGS73173.1COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (287 aa)
Your Current Organism:
Streptomyces collinus
NCBI taxonomy Id: 1214242
Other names: S. collinus Tu 365, Streptomyces collinus Tu 365
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