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ung | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (225 aa) | ||||
ligB | ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (512 aa) | ||||
AGS68139.1 | COG3663 G:T/U mismatch-specific DNA glycosylase. (176 aa) | ||||
ung-2 | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (227 aa) | ||||
AGS68679.1 | COG2094 3-methyladenine DNA glycosylase; Belongs to the DNA glycosylase MPG family. (216 aa) | ||||
AGS68895.1 | Hypothetical protein; COG1573 Uracil-DNA glycosylase. (258 aa) | ||||
polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (908 aa) | ||||
nfo | Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (274 aa) | ||||
AGS69601.1 | Endonuclease VIII and DNA N-glycosylase with an AP lyase activity; COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (269 aa) | ||||
AGS70109.1 | COG0708 Exonuclease III. (264 aa) | ||||
nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (330 aa) | ||||
AGS70927.1 | COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains. (561 aa) | ||||
AGS70989.1 | COG1194 A/G-specific DNA glycosylase. (291 aa) | ||||
AGS71087.1 | DNA polymerase related protein; COG1573 Uracil-DNA glycosylase. (219 aa) | ||||
AGS71646.1 | COG2818 3-methyladenine DNA glycosylase. (196 aa) | ||||
ligA | NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (731 aa) | ||||
mutM | Formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (286 aa) | ||||
AGS72196.1 | DNA glycosylase; COG0266 Formamidopyrimidine-DNA glycosylase. (284 aa) | ||||
AGS72584.1 | ADA-like regulatory protein; COG2169 Adenosine deaminase. (472 aa) | ||||
AGS72689.1 | COG0708 Exonuclease III. (259 aa) | ||||
AGS72733.1 | ADA-like regulatory protein; COG2169 Adenosine deaminase. (499 aa) | ||||
AGS73173.1 | COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (287 aa) |